CAS No.: 138516-31-1
Bisindolylmaleimide VIII acetate Catalog No. CSN26742
Synonyms: Ro 31-7549 acetate;Bis VIII acetate;Bisindolylmaleimide VIII (acetate)
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively[1]. Bisindolylmaleimide VIII acetate facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases[2].
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纯度 & 质量文件
批次:
靶点选择性
生物活性
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 138516-31-1 | 储存条件 |
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| 分子式 | C26H26N4O4 | 运输 | 蓝冰 | |
| 分子量 | 458.51 | 别名 | Ro 31-7549 acetate;Bis VIII acetate;Bisindolylmaleimide VIII (acetate);BIM VIII;Ro 31-7549 |
