CAS No.: 468740-43-4
BMS-536924 Catalog No. CSN16463
Synonyms: HY-10262;CS-0117
BMS-536924 is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Litzenburger BC, Kim HJ, et al. BMS-536924 reverses IGF-IR-induced transformation of mammary epithelial cells and causes growth inhibition and polarization of MCF7 cells. Clin Cancer Res. 2009 Jan 1;15(1):226-37.
- [2] Wittman M, Carboni J, et al. Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity. J Med Chem. 2005 Sep 8;48(18):5639-43.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 468740-43-4 | 储存条件 |
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| 分子式 | C25H26ClN5O3 | 运输 | 蓝冰 | |||||||||||
| 分子量 | 479.96 | 别名 | HY-10262;CS-0117 | |||||||||||
| 溶解度 |
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动物实验配方 |
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