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CAS No.: 16503-32-5
Synonyms: 6-O-Angeloylprenolin;Brevelin A;6-OAP
Brevilin A, a natural product isolated and purified from the herbs of Centipeda minima, is a strong impetus for the development of selective JAK-STAT inhibitors and therapeutic drugs in order to improve survival of patients with hyperactivated JAKs and STATs, and has antigiardial activity (IC50 = 16.1 μM) and was similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM).
生物活性
动物研究 | |
剂量 | Mice: 10 mg/kg - 20 mg/kg[3] (p.o.) |
给药途径 | p.o. |
实验方案
技术信息
CAS号 | 16503-32-5 | 储存条件 |
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分子式 | C20H26O5 | 运输 | 蓝冰 | |
分子量 | 346.42 | 别名 | 6-O-Angeloylprenolin;Brevelin A;6-OAP;6-O-Angeloylplenolin |
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