CAS No.: 1357072-61-7
c-Met inhibitor 1 Catalog No. CSN16262
c-Met Inhibitor 1 is a c-Met receptor signaling pathway inhibitor, used for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer.
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纯度 & 质量文件
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靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01610336 Non-small Cell Lung Cancer Phase 2 Active, not recruiting February 7, 2019 - NCT00726323 Carcinoma, Renal Cell Phase 2 Completed - United States, California ... more >> GSK Investigational Site Greenbrae, California, United States, 94904-2007 GSK Investigational Site San Francisco, California, United States, 94115 GSK Investigational Site Stanford, California, United States, 94305 United States, Indiana GSK Investigational Site Indianapolis, Indiana, United States, 46202 United States, Maryland GSK Investigational Site Bethesda, Maryland, United States, 20892 United States, Massachusetts GSK Investigational Site Boston, Massachusetts, United States, 02115 United States, Michigan GSK Investigational Site Detroit, Michigan, United States, 48201 United States, New Jersey GSK Investigational Site New Brunswick, New Jersey, United States, 08901 United States, Ohio GSK Investigational Site Cleveland, Ohio, United States, 44195 United States, Pennsylvania GSK Investigational Site Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37232 United States, Texas GSK Investigational Site San Antonio, Texas, United States, 78229 Collapse << NCT00725712 - - Completed - - - 更多
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1357072-61-7 | 储存条件 |
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| 分子式 | C17H14N8S | 运输 | 蓝冰 | |||
| 分子量 | 362.41 | 别名 | ||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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| NCT01610336 | Non-small Cell Lung Cancer | Phase 2 | Active, not recruiting | February 7, 2019 | - |
| NCT00726323 | Carcinoma, Renal Cell | Phase 2 | Completed | - | United States, California ... more >> GSK Investigational Site Greenbrae, California, United States, 94904-2007 GSK Investigational Site San Francisco, California, United States, 94115 GSK Investigational Site Stanford, California, United States, 94305 United States, Indiana GSK Investigational Site Indianapolis, Indiana, United States, 46202 United States, Maryland GSK Investigational Site Bethesda, Maryland, United States, 20892 United States, Massachusetts GSK Investigational Site Boston, Massachusetts, United States, 02115 United States, Michigan GSK Investigational Site Detroit, Michigan, United States, 48201 United States, New Jersey GSK Investigational Site New Brunswick, New Jersey, United States, 08901 United States, Ohio GSK Investigational Site Cleveland, Ohio, United States, 44195 United States, Pennsylvania GSK Investigational Site Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37232 United States, Texas GSK Investigational Site San Antonio, Texas, United States, 78229 Collapse << |
| NCT00725712 | - | - | Completed | - | - |
| NCT00726323 | - | - | Completed | - | - |
| NCT01892527 | Colorectal Cancer Metastatic ... more >> C-met Overexpression Collapse << | Phase 2 | Unknown | March 2017 | Italy ... more >> Istituto Clinico Humanitas Rozzano, Milano, Italy, 20089 Collapse << |
| NCT00725712 | Neoplasms, Gastrointestinal Tr... more >>act Collapse << | Phase 2 | Completed | - | United States, Alabama ... more >> GSK Investigational Site Birmingham, Alabama, United States, 35294 United States, Arizona GSK Investigational Site Scottsdale, Arizona, United States, 85258 United States, California GSK Investigational Site Los Angeles, California, United States, 90024 GSK Investigational Site Stanford, California, United States, 94305 United States, District of Columbia GSK Investigational Site Washington, D.C., District of Columbia, United States, 20007 United States, Georgia GSK Investigational Site Atlanta, Georgia, United States, 30309 United States, Illinois GSK Investigational Site Chicago, Illinois, United States, 60637 United States, Massachusetts GSK Investigational Site Boston, Massachusetts, United States, 02114 United States, Michigan GSK Investigational Site Detroit, Michigan, United States, 48201 United States, Montana GSK Investigational Site Billings, Montana, United States, 59101 United States, New Mexico GSK Investigational Site Albuquerque, New Mexico, United States, 87131 United States, New York GSK Investigational Site New York, New York, United States, 10016 GSK Investigational Site New York, New York, United States, 10021 United States, North Carolina GSK Investigational Site Durham, North Carolina, United States, 27710 United States, Oregon GSK Investigational Site Portland, Oregon, United States, 97239 United States, Texas GSK Investigational Site Austin, Texas, United States, 78705 United States, Wisconsin GSK Investigational Site Madison, Wisconsin, United States, 53792 Collapse << |
| NCT03546608 | Hepatic Impairment | Phase 1 | Recruiting | September 21, 2018 | United States, Florida ... more >> Qps Mra, Llc Not yet recruiting Miami, Florida, United States, 33143 Orlando Clinical Research Center Recruiting Orlando, Florida, United States, 32809 Collapse << |
| NCT03385655 | Prostate Cancer | Phase 2 | Recruiting | December 31, 2020 | Canada, Alberta ... more >> Cross Cancer Institute Recruiting Edmonton, Alberta, Canada, T6G 1Z2 Contact: Michael Kolinsky 780 432-8762 Canada, British Columbia BCCA - Vancouver Cancer Centre Recruiting Vancouver, British Columbia, Canada, V5Z 4E6 Contact: Kim Chi 604 877-6000 ext 2746 Canada, Nova Scotia QEII Health Sciences Centre Recruiting Halifax, Nova Scotia, Canada, B3H 1V7 Contact: Robyn J. Macfarlane 902 473-6106 Canada, Ontario Juravinski Cancer Centre at Hamilton Health Sciences Recruiting Hamilton, Ontario, Canada, L8V 5C2 Contact: Som Mukherjee 905 387-9495 ext 64605 London Regional Cancer Program Recruiting London, Ontario, Canada, N6A 5W9 Contact: Eric W. Winquist 519 685-8261 Ottawa Hospital Research Institute Recruiting Ottawa, Ontario, Canada, K1H 8L6 Contact: Michael Ong 613 737-7700 ext 75051 University Health Network Recruiting Toronto, Ontario, Canada, M5G 2M9 Contact: Adrian Sacher 416 946-4501 ext 3550 Canada, Quebec CHUM-Centre Hospitalier de l'Universite de Montreal Recruiting Montreal, Quebec, Canada, H2X 3E4 Contact: Fred Saad 514 890-8000 ext 27466 The Jewish General Hospital Recruiting Montreal, Quebec, Canada, H3T 1E2 Contact: Cristiano Ferrario 514 398-8307 Canada, Saskatchewan Allan Blair Cancer Centre Recruiting Regina, Saskatchewan, Canada, S4T 7T1 Contact: Muhammad Salim 306 766-2691 Saskatoon Cancer Centre Recruiting Saskatoon, Saskatchewan, Canada, S7N 4H4 Contact: Nayyer Iqbal 306 655-2710 Collapse << |
| NCT00939770 | ALK Fusion Protein Expression ... more >> ALK Gene Amplification ALK Gene Mutation ALK Positive c-MET Gene Amplification MET Gene Mutation Recurrent Childhood Anaplastic Large Cell Lymphoma Recurrent Malignant Solid Neoplasm Recurrent Neuroblastoma Refractory Anaplastic Large Cell Lymphoma Refractory Malignant Solid Neoplasm Refractory Neuroblastoma Collapse << | Phase 1 Phase 2 | Active, not recruiting | - | - |
| NCT02761057 | Stage III Renal Cell Cancer AJ... more >>CC v7 Stage IV Renal Cell Cancer AJCC v7 Type 1 Papillary Renal Cell Carcinoma Type 2 Papillary Renal Cell Carcinoma Unresectable Renal Cell Carcinoma Collapse << | Phase 2 | Suspended(Scheduled Interim Mo... more >>nitoring) Collapse << | - | - |
| NCT01441128 | Carcinoma, Non-Small Cell Lung... more >> Adenocarcinoma Carcinoma, Squamous Cell Carcinoma, Large Cell Collapse << | Phase 1 | Terminated | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT02759640 | Neoplasm Soli... more >>d Tumors Collapse << | Phase 1 | Active, not recruiting | March 2020 | Australia, New South Wales ... more >> Chris O'Brien Lifehouse Camperdown, New South Wales, Australia, 2050 Liverpool Liverpool, New South Wales, Australia, 2170 Collapse << |
| NCT01519414 | Hormone-Resistant Prostate Can... more >>cer Prostate Adenocarcinoma Recurrent Prostate Carcinoma Stage IV Prostate Cancer Collapse << | Phase 2 | Completed | - | United States, District of Col... more >>umbia MedStar Georgetown University Hospital Washington, District of Columbia, United States, 20007 United States, Florida Moffitt Cancer Center Tampa, Florida, United States, 33612 United States, Illinois Northwestern University Chicago, Illinois, United States, 60611 Michael Reese Hospital Chicago, Illinois, United States, 60616 University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637 Decatur Memorial Hospital Decatur, Illinois, United States, 62526 NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois, United States, 60201 Ingalls Memorial Hospital Harvey, Illinois, United States, 60426 Illinois CancerCare-Peoria Peoria, Illinois, United States, 61615 Southern Illinois University School of Medicine Springfield, Illinois, United States, 62702 United States, Indiana Fort Wayne Medical Oncology and Hematology Inc - Jefferson Boulevard Fort Wayne, Indiana, United States, 46804 Indiana University/Melvin and Bren Simon Cancer Center Indianapolis, Indiana, United States, 46202 United States, Maryland University of Maryland/Greenebaum Cancer Center Baltimore, Maryland, United States, 21201 University of Maryland Saint Joseph Medical Center Towson, Maryland, United States, 21204 United States, Missouri Mercy Hospital Saint Louis Saint Louis, Missouri, United States, 63141 United States, New York Roswell Park Cancer Institute Buffalo, New York, United States, 14263 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43210 United States, Wisconsin University of Wisconsin Hospital and Clinics Madison, Wisconsin, United States, 53792 Collapse << |
| NCT02299648 | Stomach Neoplasms | Not Applicable | Recruiting | December 2019 | Korea, Republic of ... more >> Samsung Medical center Recruiting Seoul, Korea, Republic of, 135-710 Contact: Yoonjeong Ahn 82-2-2148-7395 younjeong.ahn@samsung.com Principal Investigator: Jeeyun Lee, MD,PhD Samsung Medical Center Recruiting Seoul, Korea, Republic of Contact: Jeeyun Lee, M.D., Ph.D. 82-2-3410-3459 jyun.lee@samsung.com Collapse << |
| NCT02608411 | Carcinoma, Small Cell | Phase 2 | Terminated(Safety results (app... more >>lied in METIV-HCC trial) have led early termination) Collapse << | February 2019 | Italy ... more >> Istituto Oncologico Veneto Padova, Italy, 35128 Collapse << |
| NCT02977364 | Carcinoma Sol... more >>id Tumor, Adult Collapse << | Phase 1 | Recruiting | November 2021 | China, Beijing ... more >> Cancer Hospital Chinese Academy of Medical Sciences Recruiting Beijing, Beijing, China, 100021 Contact: Yuankai Shi, MD 86(10)87788293 syuankaipumc@126.com Collapse << |
| NCT01519414 | - | - | Completed | - | - |
| NCT01244191 | Non Squamous, Non-small-cell L... more >>ung Cancer Collapse << | Phase 3 | Completed | - | - |
| NCT00743067 | Solid Tumours | Phase 1 | Completed | - | - |
| NCT00742131 | Solid Tumours | Phase 1 | Completed | - | - |
| NCT02447380 | Advanced Gastric Adenocarcinom... more >>a Collapse << | Phase 2 | Recruiting | December 2019 | Korea, Republic of ... more >> Samsung Medical Center Recruiting Seoul, Seoul, Korea, Republic Of, Korea, Republic of, 135-710 Contact: yoon Jeong Ahn 221487395 ext 82 Principal Investigator: Seung Tae Kim, M.D., Ph.D. Collapse << |
| NCT01835145 | Recurrent Uveal Melanoma ... more >> Stage III Uveal Melanoma AJCC v7 Stage IIIA Uveal Melanoma AJCC v7 Stage IIIB Uveal Melanoma AJCC v7 Stage IIIC Uveal Melanoma AJCC v7 Stage IV Uveal Melanoma AJCC v7 Collapse << | Phase 2 | Completed | - | - |
| NCT01110083 | Solid Tumors | Phase 1 | Terminated(Please see "Purpose... more >>" statement below.) Collapse << | - | United States, Texas ... more >> M.D. Anderson Cancer Center Houston, Texas, United States Collapse << |
| NCT00788957 | Colon Cancer ... more >>Colorectal Cancer Gastrointestinal Cancer Metastatic Colorectal Cancer Rectal Cancer Collapse << | Phase 1 Phase 2 | Completed | - | - |
| NCT01014936 | Patients With Solid Tumors, Ei... more >>ther Refractory to Standard Therapy or for Which no Effective Standard Therapy is Available Collapse << | Phase 1 | Completed | - | United States, Texas ... more >> M.D. Anderson Cancer Center Houston, Texas, United States Collapse << |
| NCT00788957 | - | - | Completed | - | - |
| NCT01447914 | Refractory Multiple Myeloma | Phase 2 | Completed | - | United States, Texas ... more >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT02115373 | Carcinoma, Hepatocellular | Phase 1 Phase 2 | Completed | - | Germany ... more >> Please contact the Merck KGaA Communication Center located in Darmstadt, Germany Collapse << |
| NCT01654965 | Adult Solid Neoplasm | Phase 1 | Completed | - | United States, California ... more >> City of Hope Comprehensive Cancer Center Duarte, California, United States, 91010 USC / Norris Comprehensive Cancer Center Los Angeles, California, United States, 90033 University of California Davis Comprehensive Cancer Center Sacramento, California, United States, 95817 City of Hope South Pasadena South Pasadena, California, United States, 91030 United States, Michigan Wayne State University/Karmanos Cancer Institute Detroit, Michigan, United States, 48201 United States, Pennsylvania Penn State Milton S Hershey Medical Center Hershey, Pennsylvania, United States, 17033-0850 University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania, United States, 15232 Collapse << |
| NCT01575522 | Estrogen Receptor Negative ... more >> HER2/Neu Negative Progesterone Receptor Negative Recurrent Breast Carcinoma Stage IV Breast Cancer Triple-Negative Breast Carcinoma Collapse << | Phase 2 | Completed | - | United States, Massachusetts ... more >> Dana-Farber Cancer Institute Faulkner Hospital Boston, Massachusetts, United States, 02130 Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02215 Collapse << |
| NCT00585195 | Non-Small Cell Lung Cancer ALK... more >>-positive Non-Small Cell Lung Cancer c-Met Dependent Non-Small Cell Lung Cancer ROS Marker Positive Systemic Anaplastic Large-Cell Lymphoma Advanced Malignancies Except Leukemia Collapse << | Phase 1 | Recruiting | July 14, 2023 | - |
| NCT02019693 | Papillary Renal Cell Carcinoma | Phase 2 | Recruiting | January 1, 2021 | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office 888-624-1937 Collapse << |
| NCT01575522 | - | - | Completed | - | - |
| NCT01014936 | - | - | Completed | - | - |
| NCT01447914 | - | - | Completed | - | - |
| NCT01468922 | Sarcoma Stoma... more >>ch Neoplasms Neoplasms Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00813384 | Cancer Oncolo... more >>gy Tumors Advanced Malignancy Advanced Solid Tumors Oncology Patients Collapse << | Phase 1 | Completed | - | United States, California ... more >> Research Site Beverly Hills, California, United States, 90211 United States, Missouri Research Site St Louis, Missouri, United States, 63110 United States, Texas Research Site Houston, Texas, United States, 77030 Collapse << |
| NCT02447406 | Advanced Gastric Adenocarcinom... more >>a Collapse << | Phase 1 Phase 2 | Recruiting | January 2019 | Korea, Republic of ... more >> Samsung Medical Center Recruiting Seoul, seoul, korea, Republic of, Korea, Republic of, 135-710 Contact: yoon Jeong Ahn 221487395 ext 82 Principal Investigator: Seung Tae Kim, M.D., Ph.D. Collapse << |
| NCT02205398 | Squamous Cell Carcinoma of Hea... more >>d and Neck (SCCHN) Metastatic Colorectal Cancer Collapse << | Phase 1 | Terminated | - | United States, Massachusetts ... more >> Massachusetts General Hospital Head & Neck Boston, Massachusetts, United States, 02114 United States, New York Memorial Sloan Kettering MSKCC NY New York, New York, United States, 10017 United States, Utah University of Utah / Huntsman Cancer Institute Onc Dept Salt Lake City, Utah, United States, 84103 Belgium Novartis Investigative Site Leuven, Belgium, 3000 Canada, Ontario Novartis Investigative Site Toronto, Ontario, Canada, M5G 1X6 France Novartis Investigative Site Lyon Cedex, France, 69373 Novartis Investigative Site Toulouse Cedex 9, France, 31059 Germany Novartis Investigative Site Essen, Germany, 45147 Novartis Investigative Site Wurzburg, Germany, 97080 Italy Novartis Investigative Site Ancona, AN, Italy, 60126 Novartis Investigative Site Milano, MI, Italy, 20162 Spain Novartis Investigative Site Barcelona, Catalunya, Spain, 08003 Novartis Investigative Site Barcelona, Catalunya, Spain, 08035 Novartis Investigative Site Hospitalet de LLobregat, Catalunya, Spain, 08907 Novartis Investigative Site Valencia, Comunidad Valenciana, Spain, 46010 Collapse << |
| NCT02414139 | Carcinoma, Non-Small-Cell Lung | Phase 2 | Recruiting | September 30, 2022 | - |
| NCT01749384 | Solid Neoplasm | Phase 1 | Completed | - | United States, Pennsylvania ... more >> Penn State Milton S Hershey Medical Center Hershey, Pennsylvania, United States, 17033-0850 University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania, United States, 15232 Collapse << |
| NCT02468661 | Non-Small Cell Lung Cancer | Phase 1 Phase 2 | Recruiting | March 31, 2020 | - |
| NCT02896231 | Non-Small Cell Lung Cancer | Phase 1 | Recruiting | December 2018 | China, Guangdong ... more >> Guangdong General Hospital Recruiting Guangzhou, Guangdong, China, 510080 Contact: Jinji Yang, MD +86-20-83827812 ext 50810 yangjinji2003@163.com Principal Investigator: Yilong Wu, MD Sub-Investigator: Jinji Yang, MD Collapse << |
| NCT01625156 | Adult Solid Neoplasm | Phase 1 | Completed | - | United States, Wisconsin ... more >> University of Wisconsin Hospital and Clinics Madison, Wisconsin, United States, 53792 Wisconsin Clinical Cancer Center Milwaukee, Wisconsin, United States, 53226 Collapse << |
| NCT01253707 | Advanced Malignancy ... more >> Advanced Solid Tumors Cancer Oncology Oncology Patients Tumors Collapse << | Phase 1 | Completed | - | United States, California ... more >> Research Site Los Angeles, California, United States, 90025 United States, Georgia Research Site Atlanta, Georgia, United States, 30332 United States, Illinois Research Site Chicago, Illinois, United States, 60637 United States, Massachusetts Research Site Boston, Massachusetts, United States, 02114 United States, Michigan Research Site Detroit, Michigan, United States, 48201 United States, Ohio Research Site Columbus, Ohio, United States, 43210 United States, Tennessee Research Site Nashville, Tennessee, United States, 37232 United States, Texas Research Site Houston, Texas, United States, 77030 Collapse << |
| NCT01835184 | Recurrent Melanoma ... more >> Stage IIIA Melanoma Stage IIIB Melanoma Stage IIIC Melanoma Stage IV Melanoma Unspecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 1 | Terminated | - | United States, Georgia ... more >> Emory University/Winship Cancer Institute Atlanta, Georgia, United States, 30322 United States, Massachusetts Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, Virginia Virginia Commonwealth University Richmond, Virginia, United States, 23298 Collapse << |
| NCT00607399 | Advanced Cancer | Phase 1 | Terminated | June 2009 | United States, Arizona ... more >> Scottsdale Healthcare Scottsdale, Arizona, United States, 85258 Premiere Oncology, Arizona Scottsdale, Arizona, United States, 85260 Collapse << |
| NCT00651365 | Neoplasms | Phase 1 | Terminated(Early termination d... more >>ue to increase in serum creatinine levels and minimal PD activity.) Collapse << | - | - |
| NCT01611857 | Malignant Solid Tumour ... more >> Gastroesophageal Cancer Collapse << | Phase 1 Phase 2 | Completed | - | United States, Connecticut ... more >> Yale University School of Medicine New Haven, Connecticut, United States, 06520 United States, Florida Florida Cancer Specialists-South Fort Myers, Florida, United States, 33916 Florida Cancer Specialists-Sarasota Sarasota, Florida, United States, 34232 Florida Cancer Specialists-North St. Petersburg, Florida, United States, 33705 United States, Oklahoma Oklahoma University Oklahoma City, Oklahoma, United States, 73104 United States, South Carolina South Carolina Oncology Associates Columbia, South Carolina, United States, 29210 United States, Tennessee Tennessee Oncology - Chattanooga Chattanooga, Tennessee, United States, 37404 Tennessee Oncology, PLLC Nashville, Tennessee, United States, 37023 United States, Texas Center for Cancer and Blood Disorders Fort Worth, Texas, United States, 76104 Collapse << |
| NCT01870726 | c-MET Inhibitor; PI3K Inhibito... more >>r, PTEN Mutations, Homozygous Del. of PTEN or PTEN Neg. by IHC, c-Met Ampli. by FISH, INC280, BKM120, Buparlisib; Recurrent GBM Collapse << | Phase 1 Phase 2 | Terminated | - | United States, Massachusetts ... more >> Dana Farber Cancer Institute SC Boston, Massachusetts, United States, 02215 United States, New York Columbia University Medical Center- New York Presbyterian Dept of Oncology New York, New York, United States, 10032 Memorial Sloan Kettering Cancer Center Neurology New York, New York, United States, 90033 United States, North Carolina Duke University Medical Center Duke - Baker Durham, North Carolina, United States, 27710 United States, Texas University of Texas MD Anderson Cancer Center SC-3 Houston, Texas, United States, 77030 Germany Novartis Investigative Site Bonn, Germany, 53105 Novartis Investigative Site Heidelberg, Germany, 69120 Novartis Investigative Site Tübingen, Germany, 72076 Netherlands ErasmusMC Cancer Institute - Neurooncology, RM G3-55 Rotterdam, Netherlands, 3075EA University Medical Center Utrecht, Rm Q05.4.300, P.O. Box 85500 Utrecht, Netherlands, 3508 GA Spain Novartis Investigative Site Barcelona, Catalunya, Spain, 08035 Novartis Investigative Site Madrid, Spain, 28041 Switzerland Novartis Investigative Site St. Gallen, Switzerland, 9007 Collapse << |
| NCT00606879 | Advanced Cancer | Phase 1 | Terminated | June 2009 | United States, California ... more >> Premier Onocology, California Santa Monica, California, United States, 90404 United States, Tennessee Sarah Cannon Research Institute Nashville, Tennessee, United States, 37203 Collapse << |
| NCT02474537 | Hepatic Impairment | Phase 1 | Completed | - | United States, Florida ... more >> University of Miami Miller School of Medicine Clinical Resea Oncology Miami, Florida, United States, 33136 Clinical Pharmacology of Miami, LLC. Miami, Florida, United States, 33142 Orlando Clinical Research Center Orlando, Florida, United States, 32086 United States, Minnesota DaVita Clinical Research Minneapolis, Minnesota, United States, 55404 United States, North Carolina Duke University Medical Center Oncology Durham, North Carolina, United States, 27710 Collapse << |
| NCT01611857 | - | - | Completed | - | - |
| NCT01870726 | - | - | Terminated | - | - |
| NCT01441388 | Carcinoma, Renal Cell ... more >> Glioblastoma Carcinoma, Hepatocellular Collapse << | Phase 1 | Withdrawn(Business/Operational... more >> issues) Collapse << | November 2013 | - |
| NCT01999972 | Advanced Solid Tumors | Phase 1 | Active, not recruiting | July 31, 2018 | United States, Illinois ... more >> University of Chicago Medical Center Chicago, Illinois, United States, 60637 United States, Indiana Investigational Drug Services IUHSCC Indianapolis, Indiana, United States, 46202 IU Health University Hospital Indianapolis, Indiana, United States, 46202 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 United States, Michigan Wayne State University, Dept. of Oncology Detroit, Michigan, United States, 48201 United States, Minnesota University of Minnesota Health Clinics and Surgery Center Minneapolis, Minnesota, United States, 55455 University of Minnesota Medical Center, Fairview IDS Pharmacy Minneapolis, Minnesota, United States, 55455 University of Minnesota Medical Center, Fairview Minneapolis, Minnesota, United States, 55455 University of Minnesota Physicians Masonic Cancer Center Minneapolis, Minnesota, United States, 55455 United States, Ohio Cleveland Clinic Cleveland, Ohio, United States, 44195 United States, Utah Huntsman Cancer Hospital Salt Lake City, Utah, United States, 84112 Huntsman Cancer Institute Salt Lake City, Utah, United States, 84112 John A Moran Eye Center Salt Lake City, Utah, United States, 84132 United States, Wisconsin University Station Ophthalmology Clinic Madison, Wisconsin, United States, 53705 University of Wisconsin Hospital and Clinics Madison, Wisconsin, United States, 53792 United Kingdom St Bartholomew's Hospital - Barts Health NHS Trust London, United Kingdom, EC1A 7BE The Royal Marsden NHS Foundation Trust, Royal Marsden Hospital London, United Kingdom, SW3 6JJ Collapse << |
| NCT01911507 | Recurrent Non-small Cell Lung ... more >>Cancer Collapse << | Phase 1 | Recruiting | December 2018 | United States, California ... more >> University of California, Davis Recruiting Sacramento, California, United States, 95817 Contact: Corinne Turrell 916-734-3089 corinne.turrell@ucdmc.ucdavis.edu Principal Investigator: Karen L. Kelly UCSF Helen Diller Family Comprehensive Cancer Center Active, not recruiting San Francisco, California, United States, 94115 Collapse << |
| NCT02335944 | Non Small Cell Lung Cancer | Phase 1 Phase 2 | Recruiting | December 23, 2019 | United States, California ... more >> City of Hope National Medical Center SC Completed Duarte, California, United States, 91010 United States, Florida H. Lee Moffitt Cancer Center & Research Institute H Lee Moffitt Completed Tampa, Florida, United States, 33612 United States, Massachusetts Massachusetts General Hospital Mass General Recruiting Boston, Massachusetts, United States, 02114 Contact: Lecia Sequist 617-724-4000 Contact: Beth Kennedy +1 617 724 1223 EAKENNEDY@mgh.harvard.edu Principal Investigator: Lecia Sequist Australia, Victoria Novartis Investigative Site Active, not recruiting Melbourne, Victoria, Australia, 3000 Canada, Alberta Novartis Investigative Site Active, not recruiting Edmonton, Alberta, Canada, T6G 1Z2 France Novartis Investigative Site Active, not recruiting Marseille cedex 05, France, 13385 Novartis Investigative Site Completed Villejuif Cedex, France, 94805 Germany Novartis Investigative Site Active, not recruiting Heidelberg, Baden-Württemberg, Germany, 69126 Novartis Investigative Site Active, not recruiting Koeln, Nordrhein-Westfalen, Germany, 50937 Italy Novartis Investigative Site Active, not recruiting Bologna, BO, Italy, 40138 Novartis Investigative Site Completed Modena, MO, Italy, 41124 Novartis Investigative Site Active, not recruiting Perugia, PG, Italy, 06129 Korea, Republic of Novartis Investigative Site Active, not recruiting Seoul, Korea, Korea, Republic of, 05505 Norway Novartis Investigative Site Active, not recruiting Oslo, Norway, NO-0424 Singapore Novartis Investigative Site Active, not recruiting Singapore, Singapore, 119228 Novartis Investigative Site Active, not recruiting Singapore, Singapore, 169610 Spain Novartis Investigative Site Active, not recruiting Barcelona, Catalunya, Spain, 08035 Novartis Investigative Site Active, not recruiting La Coruna, Galicia, Spain, 15006 Novartis Investigative Site Active, not recruiting Las Palmas De Gran Canarias, Las Palmas De Gran Canaria, Spain, 35016 Novartis Investigative Site Active, not recruiting Madrid, Spain, 28007 Novartis Investigative Site Active, not recruiting Madrid, Spain, 28041 Taiwan Novartis Investigative Site Active, not recruiting Taipei, Taiwan ROC, Taiwan, 10041 Collapse << |
| NCT03243643 | Advanced Cancer | Phase 1 | Recruiting | December 2019 | China ... more >> West China Hospital, Sichuan University Recruiting Chendu, China Contact: Feng Bi, Ph.D 028-85423203 bifeng@medmail.com.cn Collapse << |
| NCT03240393 | Carcinoma Non... more >>-Small-Cell Lung Cancer Collapse << | Phase 2 | Withdrawn(Company Decision) | October 26, 2021 | - |
| NCT02344810 | Adenocarcinoma of the Esophagu... more >>s Adenocarcinoma of the Gastroesophageal Junction Diffuse Adenocarcinoma of the Stomach Gastrointestinal Cancer Intestinal Adenocarcinoma of the Stomach Mixed Adenocarcinoma of the Stomach Stage IIIA Esophageal Cancer Stage IIIA Gastric Cancer Stage IIIB Esophageal Cancer Stage IIIB Gastric Cancer Stage IIIC Esophageal Cancer Stage IIIC Gastric Cancer Stage IV Esophageal Cancer Stage IV Gastric Cancer Collapse << | Phase 1 Phase 2 | Withdrawn(The study did not op... more >>en to accrual. No start date and no completion dates.) Collapse << | March 6, 2020 | United States, Pennsylvania ... more >> ECOG-ACRIN Cancer Research Group Philadelphia, Pennsylvania, United States, 19103 Collapse << |
| NCT03201250 | Multiple Myeloma ... more >> Refractory Multiple Myeloma Relapsed/Refractory Multiple Myeloma Collapse << | Phase 1 Phase 2 | Recruiting | October 2021 | United States, Nebraska ... more >> University of Nebraska Medical Center Recruiting Omaha, Nebraska, United States, 68198 Contact: Penny Nurse Coordinator, RN 402-559-4135 penny.hardiman@unmc.edu Collapse << |
| NCT01725191 | Childhood Solid Neoplasm | Phase 1 | Completed | - | - |
| NCT02978261 | Glioma | Phase 1 | Recruiting | December 2018 | China, Beijing ... more >> Beijing Shijitan Hospital,CMU Recruiting Beijing, Beijing, China, 100038 Contact: Xun Kang, Master +86-10-63926527 414569017@qq.com Principal Investigator: Wenbin Li, MD Sub-Investigator: Xun Kang, Master Collapse << |
| NCT02510001 | Solid Tumor C... more >>olorectal Cancer Collapse << | Phase 1 | Active, not recruiting | September 2019 | United Kingdom ... more >> Oxford University Hospital NHS Trust Oxford, United Kingdom, OX3 7LE Collapse << |
| NCT01832506 | Solid Tumors | Phase 1 | Completed | - | Japan ... more >> Research site Kashiwa, Japan Research site Shizuoka, Japan Collapse << |
| NCT01832506 | - | - | Completed | - | - |
| NCT03655613 | Hepatocellular Carcinoma ... more >> Renal Cell Carcinoma Collapse << | Phase 1 Phase 2 | Recruiting | December 15, 2020 | Australia, New South Whales ... more >> Crown Princess Mary Cancer Centre Recruiting Westmead, New South Whales, Australia, 2145 Contact: Joanna Jackson +61 (2) 8890 8377 joanna.jackson@sydney.edu.au Principal Investigator: Mark Y Wong, MD Australia, South Australia Ashford Cancer Center Recruiting Adelaide, South Australia, Australia, 5037 Contact: Helen Daykin +61 (0)882922220 hdaykin@adelaidecancercentre.com.au Principal Investigator: Amy Hsieh Australia, Victoria Royal Melbourne Hospital Recruiting Melbourne, Victoria, Australia, 3050 Contact: Irene Bell +61(0)393482004 irene.bell@mh.org.au Principal Investigator: Siddharth Sood, MD Australia, Western Australia Fiona Stanley Hospital Recruiting Murdoch, Western Australia, Australia, 6150 Contact: Caroline Stone +61(8) 6152 6530 caroline.stone@health.wa.gov.au Contact: Muhammad A Khattak, MD Principal Investigator: Muhammad A Khattak, MD Afffinity Clinical Research Recruiting Perth, Western Australia, Australia, 6018 Contact: Krystyne Hiscock +61 (0)8 9446 8726 pm1@affinityresearch.com.au Principal Investigator: Alex Powell, MD New Zealand Auckland City Hospital Recruiting Auckland, New Zealand, 1023 Contact: Sarah Coates +64 9529 4001 scoates@adhb.govt.nz Contact: Bibin George +64 9529 4001 BibinG@adhb.govt.nz Principal Investigator: Edward Gane, MD Collapse << |
| NCT01121575 | Non Small Cell Lung Cancer | Phase 1 | Completed | - | United States, Colorado ... more >> Clinical Trials Office University of Colorado Hospital (CTO) Aurora, Colorado, United States, 80045 DRUG SHIPMENT: University of Colorado Cancer Center Aurora, Colorado, United States, 80045 Rocky Mountain Lions Eye Institute Aurora, Colorado, United States, 80045 University of Colorado Hospital Aurora, Colorado, United States, 80045 United States, Maryland CCR, National Cancer Institute Bethesda, Maryland, United States, 20892 United States, Massachusetts Drug Shipment Only Boston, Massachusetts, United States, 02114 Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Brigham & Women's Hospital Boston, Massachusetts, United States, 02115 Drug Shipment Only Boston, Massachusetts, United States, 02215 Australia, Victoria Peter MacCallum Cancer Centre, Division of Haematology and Medical Oncology East Melbourne, Victoria, Australia, 3002 Collapse << |
| NCT02386826 | Glioblastoma Multiforme ... more >> Gliosarcoma Colorectal Cancer Renal Cell Carcinoma Collapse << | Phase 1 | Recruiting | November 2019 | United States, Colorado ... more >> Sarah Cannon Research Institute at HealthONE Recruiting Denver, Colorado, United States, 80218 United States, Connecticut Yale School of Medicine Recruiting New Haven, Connecticut, United States, 06520 United States, Missouri HCA Midwest - Kansas City Recruiting Kansas City, Missouri, United States, 64132 United States, Oklahoma Oklahoma University Health Science Center Recruiting Oklahoma City, Oklahoma, United States, 73104 United States, Tennessee Tennessee Oncology PLLC Recruiting Nashville, Tennessee, United States, 37203 Collapse << |
| NCT01121575 | - | - | Completed | - | - |
| 靶点 | Description | IC50 |
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