CAS No.: 1369665-02-0
Cobimetinib hemifumarate/考比替尼半富马酸盐 Catalog No. CSN26697
Synonyms: GDC-0973 hemifumarate;XL-518 hemifumarate;XL-518
Cobimetinib, also known as GDC-0973 and XL-518, RG 7420, is an orally bioavailable small-molecule inhibitor of mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity. MEK inhibitor GDC-0973 specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of extracellular signal-related kinase 2 (ERK2) phosphorylation and activation and decreased tumor cell proliferation. Preclinical studies have demonstrated that this agent is effective in inhibiting the growth of tumor cells bearing a B-RAF mutation, which has been found to be associated with many tumor types.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1369665-02-0 | 储存条件 |
|
|
| 分子式 | C25H25F3IN3O6 | 运输 | 蓝冰 | |
| 分子量 | 647.38 | 别名 | GDC-0973 hemifumarate;XL-518 hemifumarate;XL-518;GDC-0973;RG-7420;cobimetinib;Cotellic;考比替尼半富马酸盐 |
