CAS No.: 934662-91-6
Cobimetinib racemate/考比替尼 (外消旋体) Catalog No. CSN18601
Synonyms: GDC-0973 racemate;XL518 racemate;XL 518
Cobimetinib is a potent, highly selective inhibitor of MEK1/2.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Choo EF, Ng CM, et al. PK-PD modeling of combination efficacy effect from administration of the MEK inhibitor GDC-0973 and PI3K inhibitor GDC-0941 in A2058 xenografts. Cancer Chemother Pharmacol. 2013 Jan;71(1):133-43.
- [2] Hoeflich KP, Merchant M,et al. Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition. Cancer Res. 2012 Jan 1;72(1):210-9.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 934662-91-6 | 储存条件 |
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| 分子式 | C21H21F3IN3O2 | 运输 | 蓝冰 | |
| 分子量 | 531.31 | 别名 | GDC-0973 racemate;XL518 racemate;XL 518;GDC0973;考比替尼 (外消旋体) |
