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CAS No.: 921625-62-9
Synonyms: 半胱氨酸蛋白酶抑制剂
Cysteine protease inhibitor is an inhibitor of cysteine protease.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00157508 | Type 2 Diabetes ... more >> Early Nephropathy Collapse << | Phase 2 | Terminated | - | Italy ... more >> Clinical Research Center for Rare Diseases Ranica, Bergamo, Italy, 24020 Collapse << |
NCT00166166 | Hyperlipidemia | Phase 2 | Terminated(Limited clinical st... more >>aff) Collapse << | - | United States, Georgia ... more >> Emory University School of Medicine Atlanta, Georgia, United States, 30322 Collapse << |
NCT00166166 | - | - | Terminated(Limited clinical st... more >>aff) Collapse << | - | - |
实验方案
技术信息
CAS号 | 921625-62-9 | 储存条件 |
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分子式 | C18H14N4O | 运输 | 蓝冰 | |
分子量 | 302.33 | 别名 | 半胱氨酸蛋白酶抑制剂 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00157508 | Type 2 Diabetes ... more >> Early Nephropathy Collapse << | Phase 2 | Terminated | - | Italy ... more >> Clinical Research Center for Rare Diseases Ranica, Bergamo, Italy, 24020 Collapse << |
NCT00166166 | Hyperlipidemia | Phase 2 | Terminated(Limited clinical st... more >>aff) Collapse << | - | United States, Georgia ... more >> Emory University School of Medicine Atlanta, Georgia, United States, 30322 Collapse << |
NCT00166166 | - | - | Terminated(Limited clinical st... more >>aff) Collapse << | - | - |
NCT00331786 | Colorectal Cancer | Phase 1 | Completed | - | United States, New York ... more >> Stony Brook University Cancer Center Stony Brook, New York, United States, 11794-8174 Collapse << |
NCT00399256 | Chronic Kidney Failure | Not Applicable | Terminated | - | Germany ... more >> Robert-Bosch-Hospital Stuttgart, Germany, D-70376 Collapse << |
NCT00170911 | Osteoporosis | Phase 2 | Completed | - | - |
NCT02113150 | Coronary Artery Disease | Phase 4 | Completed | - | Turkey ... more >> Aslı Demir Ankara, Turkey, 06100 Turkey Yuksek Ihtisas Education and Research Hospital Ankara, Turkey, 06550 Collapse << |
NCT02189122 | Healthy | Not Applicable | Completed | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Collapse << |
NCT02341300 | Iron-deficiency Anemia | Not Applicable | Recruiting | November 2020 | United States, New York ... more >> New York Prebyterian Hospital Weill Cornell Recruiting New York, New York, United States, 10021 Contact: Shari Gelber, MD 212-746-3182 shg7001@med.cornell.edu Contact: Chelsea Clinton, MD 734-223-6103 cmk9008@nyp.org Sub-Investigator: Chelsea Clinton, MD Principal Investigator: Shari Gelber, MD Sub-Investigator: Melissa Yoffee, RD Collapse << |
NCT03738878 | Hypertension | Phase 4 | Recruiting | December 31, 2020 | United States, Tennessee ... more >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37205 Contact: Nancy J Brown, MD 615-343-8701 Contact: Dustin Mayfield, RN 615-343-8701 Collapse << |
NCT01256775 | Intermittent Claudication | Phase 2 | Completed | - | Italy ... more >> Ospedale di Perugia Perugia, Italy, 06126 Collapse << |
NCT00868855 | Coronary Artery Disease | Phase 1 | Terminated(poor enrollment) | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Collapse << |
NCT00223704 | - | - | Completed | - | - |
NCT02189122 | - | - | Completed | - | - |
NCT00965120 | Ischaemic Heart Diseases | Not Applicable | Completed | - | United Kingdom ... more >> University of Edinburgh, 49 Little France Crescent Edinburgh, United Kingdom, EH16 4SB Collapse << |
NCT00685945 | - | - | Completed | - | - |
NCT00517582 | Angioneurotic Edema | Phase 1 | Terminated(This study was stop... more >>ped to allow initiation of a mult-center study) Collapse << | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37205 Collapse << |
NCT00685945 | Obesity | Not Applicable | Completed | - | United States, Tennessee ... more >> Vanderbilt University Medical Center-GCRC Nashville, Tennessee, United States, 37232 Collapse << |
NCT03030703 | Iron-deficiency ... more >> Iron Deficiency Anemia Collapse << | Not Applicable | Completed | - | United States, Kansas ... more >> Physical Activity and Nutrition Research Consortium Manhattan, Kansas, United States, 66502 Collapse << |
NCT00223704 | Cardiopulmonary Bypass ... more >> Inflammation Fibrinolysis Surgery Collapse << | Phase 2 Phase 3 | Completed | - | United States, Tennessee ... more >> TN Valley Healthcare System Nashville, Tennessee, United States, 37212 Vanderbilt University Nashville, Tennessee, United States, 37232 Collapse << |
NCT01574248 | ACE Inhibitor-associated Angio... more >>edema Collapse << | Phase 4 | Terminated(DSMC recommended di... more >>scontinuation for futility and feasibility) Collapse << | - | United States, California ... more >> University of California, San Diego San Diego, California, United States, 92093 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37235 Collapse << |
NCT01413542 | Hypertension ... more >>Diabetes Type 2 Collapse << | Not Applicable | Completed | - | United States, Tennessee ... more >> Vanderbilt University- General Clinic Research Center Nashville, Tennessee, United States, 37232 Collapse << |
NCT00965393 | Ischaemic Heart Diseases | Not Applicable | Completed | - | United Kingdom ... more >> University of Edinburgh, 49 Little France Crescent Edinburgh, United Kingdom, EH16 4SB Collapse << |
NCT01137942 | - | - | Unknown | July 2010 | Slovenia ... more >> Abakus Medico Recruiting Rogaska Slatina, Slovenia Contact: Bojan Tepes, MD. PhD +386 (0) 3 819 14 11 abakus.medico@volja.net Principal Investigator: Bojan Tepes, MD, Phd Sub-Investigator: Miha Skvarc, MD Collapse << |
NCT00083356 | Tooth, Impacted | Phase 2 | Completed | - | United States, Maryland ... more >> National Institute of Nursing Research (NINR) Bethesda, Maryland, United States, 20892 Collapse << |
NCT01574248 | - | - | Terminated(DSMC recommended di... more >>scontinuation for futility and feasibility) Collapse << | - | - |
NCT00780377 | Heart Transplantation | Not Applicable | Withdrawn(Unable to perform st... more >>udy due to unavailable drug, then unable to partner with cath lab) Collapse << | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Collapse << |
NCT00780481 | - | - | Terminated(Lack of enrollment ... more >>due to strict inclusion/exclusion criteria. Bradykinin shortage) Collapse << | - | - |
NCT00300066 | - | - | Completed | - | Denmark ... more >> Department of Nuclear Medicine, University Hospital Aarhus, Skejby Aarhus, Brendstrupgaardsvej 100, Denmark, 8200 Department of Clinical Physiology, University Hospital of Aarhus, Aalborg Aalborg, Hobrovej 18-22, Denmark, 9000 Collapse << |
NCT00462527 | - | - | Completed | - | Canada, Ontario ... more >> Department of Pediatric Emergency, Children's Hospital of Eastern Ontario Ottawa, Ontario, Canada, K1H 8L1 Collapse << |
NCT00467311 | - | - | Completed | - | Mexico ... more >> Ignacio Chávez National Institute of Cardiology Mexico City, DF, Mexico, 01480 Collapse << |
NCT01413542 | - | - | Completed | - | - |
NCT00780481 | Obesity | Not Applicable | Terminated(Lack of enrollment ... more >>due to strict inclusion/exclusion criteria. Bradykinin shortage) Collapse << | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Collapse << |
NCT00504855 | Pressure Ulcer | Not Applicable | Terminated(Staffing changes re... more >>sulted in the expiration of IRB approval (2/15/12), and recruitment halted (n=84). IRB approval is now current for retrospective analysis.) Collapse << | March 2014 | United States, Hawaii ... more >> Shriners Hospitals for Children - Honolulu Honolulu, Hawaii, United States, 96826 Collapse << |
NCT01114074 | - | - | Unknown | April 2017 | Netherlands ... more >> Maastricht University Maastricht, Limburg, Netherlands, 6229 ER Collapse << |
NCT00704743 | Colles' Fracture | Phase 3 | Completed | - | Canada, British Columbia ... more >> Department of Emergency Medicine, St Paul's Hospital Vancouver, British Columbia, Canada, V1Y 1Z1 Collapse << |
NCT00823823 | Displaced Forearm Fractures | Not Applicable | Completed | - | United States, Massachusetts ... more >> Childrens Hospital Boston Boston, Massachusetts, United States, 02125 Collapse << |
NCT00916539 | Non-displaced Scaphoid Fractur... more >>es Collapse << | Not Applicable | Completed | - | United States, Massachusetts ... more >> Massachusettes General Hospital Boston, Massachusetts, United States, 02114 Collapse << |
NCT00823823 | - | - | Completed | - | - |
NCT01221207 | Diabetic Foot Ulcers | Not Applicable | Unknown | October 2012 | United States, Arizona ... more >> University of Arizona Recruiting Tucson, Arizona, United States Contact: David Armstrong, D 520-626-1349 United States, Texas Parkland Health & Hospital Systems Not yet recruiting Dallas, Texas, United States, 75235 Contact: Lawrence Lavery, DPM 214-645-0544 LLAVE1@mednet.swmed.edu Contact: Cecilia Lara 214-645-2377 cecilia.lara@utsouthwestern.edu UT Southwestern Medical Center at Dallas Not yet recruiting Dallas, Texas, United States, 75390 Contact: Lawrence Lavery, DPM 214-645-0544 LLAVE1@mednet.swmed.edu Contact: Cecilia Lara 214-645-2377 cecilia.lara@utsouthwestern.edu Scott & White Recruiting Temple, Texas, United States Contact: Douglas Murdoch, DPM 214-771-7604 DMurdoch@swmail.sw.org Collapse << |
NCT00780637 | Heart Transplantation | Not Applicable | Withdrawn(Bradykinin Shortage,... more >> SCCOR expired prior to BK availability, lack of enrollment.) Collapse << | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Collapse << |
NCT01238523 | Tibial Shaft Fractures in Chil... more >>dren Collapse << | Not Applicable | Completed | - | United States, California ... more >> Los Angeles Orthopaedic Hospital Los Angeles, California, United States, 90007 Collapse << |
NCT01403766 | - | - | Unknown | December 2012 | United States, California ... more >> University of California, Los Angeles Not yet recruiting Los Angeles, California, United States, 90095 Contact: Eileen Tsai, M.D. 310-206-8415 etsai@mednet.ucla.edu Principal Investigator: Eileen Tsai, M.D. Sub-Investigator: John Nguyen, M.D. Collapse << |
NCT00561483 | - | - | Completed | - | United States, Ohio ... more >> Cleveland Clinic Cleveland, Ohio, United States, 44195 Collapse << |
NCT01652755 | - | - | Unknown | May 2013 | China, Zhejiang ... more >> Jinhua central hospital Recruiting Jinhua, Zhejiang, China, 321000 Contact: Hongying Ni, MM 86 ext 57982552629 nihongying2@163.com Principal Investigator: Hongying Ni, MM Collapse << |
NCT01758835 | Lateral Malleolus Fractures | Not Applicable | Completed | - | Finland ... more >> OYS, kirurgian klinkka, Oulu Oulu, Finland, 90100 Collapse << |
NCT01318746 | - | - | Completed | - | Germany ... more >> Clinical Research Unit, Department of Nephrology and Hypertension, University of Erlangen-Nürnberg Erlangen, Germany, 91054 Collapse << |
NCT02047240 | - | - | Completed | - | Mexico ... more >> Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán" Mexico City, DF, Mexico, 14000 Collapse << |
NCT01908309 | Contrast Induced Acute Kidney ... more >>Injury Collapse << | Early Phase 1 | Completed | - | Italy ... more >> Misericordia Hospital, ASL 9 Grosseto, Italy, 58100 Collapse << |
NCT02066857 | Radius; Fracture, Lower or Dis... more >>tal End Collapse << | Not Applicable | Completed | - | United States, Georgia ... more >> Emory Orthopaedics and Spine Center Atlanta, Georgia, United States, 30329 Collapse << |
NCT02095106 | Pediatric Distal Radius Fractu... more >>res Collapse << | Not Applicable | Completed | - | United States, California ... more >> Orthopaedic Institute for Children Los Angeles, California, United States, 90007 Collapse << |
NCT02095106 | - | - | Completed | - | - |
NCT02233179 | Diabetic Foot | Not Applicable | Completed | - | United States, Arizona ... more >> University Medical Center Tucson, Arizona, United States, 85724 Collapse << |
NCT02066857 | - | - | Completed | - | - |
NCT02334033 | - | - | Completed | - | Turkey ... more >> Ankara University School Of Medicine, Department of Cardiology Ankara, Turkey, 06230 Collapse << |
NCT02433002 | - | - | Active, not recruiting | December 31, 2019 | United Kingdom ... more >> Derby Hospitals NHS Foundation Trust (Royal Derby Hospital) Derby, Derbyshire, United Kingdom, DE22 3NE King's College Hospital NHS Foundation Trust London, Greater London, United Kingdom, SE5 NRS Salford Royal NHS Foundation Trust (Salford Royal Hospital) Salford, Greater Manchester, United Kingdom, M6 8HD East Kent Hospitals NHS Trust (Kent & Canterbury Hospital) Canterbury, Kent, United Kingdom, CT1 3NG University Hospitals of Leicester NHS Trust (Leicester General Hospital) Leicester, Leicestershire, United Kingdom, LE54PW University Hospital Birmingham NHS Trust (Queen Elizabeth Hospital Birmingham) Birmingham, West Midlands, United Kingdom, B15 2TH Collapse << |
NCT02614690 | Fracture of Shaft of Radius an... more >>d/or Ulna Metaphyseal Fracture of Bone of Upper Limb Fracture of Upper Limb, Level Unspecified Collapse << | Not Applicable | Unknown | January 2017 | United States, Connecticut ... more >> Connecticut Children's Medical Center Recruiting Hartford, Connecticut, United States, 06016 Contact: Matt Solomito 860-284-0208 mailto:msolomito@ccmckids.org Principal Investigator: Mark Lee, MD Collapse << |
NCT00916539 | - | - | Completed | - | - |
NCT02822404 | Kidney Diseases | Not Applicable | Active, not recruiting | September 2020 | France ... more >> CHU Toulouse Toulouse, France, 31059 Collapse << |
NCT02894164 | - | - | Completed | - | Sweden ... more >> Karolinska Institute Stockholm, Sweden, 171 77 Collapse << |
NCT02894983 | Colles' Fracture ... more >> Distal Radius Fracture Collapse << | Not Applicable | Completed | - | Finland ... more >> Central Finland Central Hospital Jyväskylä, Finland Satakunta Central Hospital Pori, Finland Tampere Univeristy Hospital Tampere, Finland Collapse << |
NCT02276066 | Sepsis | Phase 4 | Recruiting | April 2020 | United States, Florida ... more >> UF Health at Shands hospital Recruiting Gainesville, Florida, United States, 32610 Contact: Jennifer Lanz, MSN 352-273-5497 jennifer.lanz@surgery.ufl.edu Contact: Ruth Davis, ASN 325-273-5497 ruth.davis@surgery.ufl.edu Collapse << |
NCT01474473 | Foot Ulcer Di... more >>abetes Mellitus Diabetic Neuropathy Collapse << | Not Applicable | Completed | - | France ... more >> Pitié-Salpêtrière Hospital Paris, France, 75013 Collapse << |
NCT03297047 | Salter-Harris Type I ... more >> Salter-Harris Type 2 Radius Fractures Forearm Fracture Collapse << | Not Applicable | Not yet recruiting | June 30, 2019 | - |
NCT03468023 | Radius Fracture Distal | Not Applicable | Recruiting | October 20, 2019 | Italy ... more >> Ospedale Civile Maggiore Borgo Trento Recruiting Verona, Italy, 37126 Contact: Giovanni Dib, MD +39 349 121 4908 dib.giovanni@gmail.com Contact: Matteo Cengarle, MD +39 340 981 7025 matteo_29@hotmail.com Collapse << |
NCT03240471 | Distal Radius Fracture | Not Applicable | Active, not recruiting | December 2019 | Netherlands ... more >> Rijnstate hospital Arnhem, Netherlands Ziekenhuis Gelderse Vallei Ede, Netherlands Radboudumc Nijmegen, Netherlands Collapse << |
NCT03486184 | - | - | Not yet recruiting | April 30, 2020 | - |
NCT03610191 | - | - | Recruiting | July 1, 2020 | China, Shaanxi ... more >> Xijing Hospital Recruiting Xi'an, Shaanxi, China, 710032 Contact: Jing Zhao, M.D. 13892810471 Contact: Lihong Hou, M.D., Ph.D. +862984775337 Collapse << |
NCT03170687 | Acute Closed Fracture of Proxi... more >>mal Fifth Metatarsal (Zone II) Collapse << | Not Applicable | Completed | - | Thailand ... more >> Jatupon Kongtharvonskul Bangkok, Select..., Thailand, 10400 Collapse << |
NCT03751397 | - | - | Not yet recruiting | December 2019 | Switzerland ... more >> University of Basel Children's Hospital Not yet recruiting Basel, Switzerland, 4031 Contact: Tatjana Welzel, Dr. med +41 (0)61 704 18 17 tatjana.welzel@ukbb.ch Collapse << |
NCT00080236 | Liver Transplantation ... more >> Hepatitis Cholestasis Carcinoma, Hepatocellular Collapse << | Phase 2 | Completed | - | United States, Arizona ... more >> Mayo Clinic Scottsdale Phoenix, Arizona, United States, 85054 United States, California University of California Los Angeles Los Angeles, California, United States, 90095 University of California San Francisco San Francisco, California, United States, 94143 United States, Indiana Indiana University Medical Center Indianapolis, Indiana, United States, 46202 United States, Louisiana Tulane University Hospital and Clinic New Orleans, Louisiana, United States, 70112 United States, Minnesota Mayo Clinic Rochester Rochester, Minnesota, United States, 55905 United States, New York Mount Sinai School of Medicine New York City, New York, United States, 10029 United States, Ohio University of Cincinnati Cincinnati, Ohio, United States, 45267 United States, Texas Baylor Regional Transplant Institute, Baylor University Medical Center Dallas, Texas, United States, 75246 The University of Texas Health Science Center at San Antonio San Antonio, Texas, United States, 78229 Germany Oberarzt der Klinik für Allgemein-, Viszeral- und Transplantationschirurgie Charité-Virchow Berlin, Germany, D-13353 Klinik für Viszeral- und Transplantationschirurgie Medizinische Hochschule Hannover Hannover, Germany, D-30623 Abteilung für Transplantationschirurgie Johannes Gutenberg-Universität Mainz Mainz, Germany, 55101 Collapse << |
NCT00088140 | Hepatitis C, Chronic | Phase 2 | Completed | - | United States, Arizona ... more >> Mayo Clinic Hospital Phoenix, Arizona, United States, 85054 United States, California Scripps Clinic La Jolla, California, United States, 92067 California Pacific Medical Center San Francisco, California, United States, 94115 University of California, San Francisco San Francisco, California, United States, 94143 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, Indiana Indiana University School of Medicine Indianapolis, Indiana, United States, 46202 United States, Massachusetts Beth Israel Deaconness Medical Center Boston, Massachusetts, United States, 02215 United States, Michigan Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, Minnesota The Mayo Clinic Rochester, Minnesota, United States, 55905 United States, New York Mt. Sinai School of Medicine New York City, New York, United States, 10029 United States, North Carolina University of North Carolina Chapel Hill, North Carolina, United States, 27599 Duke University Medical Center Durham, North Carolina, United States, 27715 United States, Ohio University of Cincinnati Cincinnati, Ohio, United States, 45267 Metrohealth Medical Center Cleveland, Ohio, United States, 44109 United States, Virginia Medical College of Virginia Richmond, Virginia, United States, 23298 Collapse << |
NCT02686762 | Non-alcoholic Steatohepatitis ... more >> Fibrosis Liver Diseases Collapse << | Phase 2 | Active, not recruiting | January 2019 | - |
NCT01653899 | Diabetes | Phase 1 Phase 2 | Completed | - | Canada, Alberta ... more >> University of Alberta Edmonton, Alberta, Canada Collapse << |
NCT03617055 | - | - | Not yet recruiting | July 1, 2020 | - |
NCT02960204 | Cirrhosis Por... more >>tal Hypertension Non-alcoholic Steatohepatitis Collapse << | Phase 2 | Active, not recruiting | April 2019 | - |
NCT03205345 | Decompensated Cirrhosis | Phase 2 | Recruiting | August 2019 | - |
NCT02798614 | Colles' Fracture | Not Applicable | Completed | - | - |
NCT02945241 | Methicillin-resistant Staphylo... more >>coccus Aureus Sepsis Critical Illness Collapse << | Phase 1 | Completed | - | - |
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