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CAS No.: 58-95-7

D-α-Tocopherol acetate/生育酚乙酸酯 Catalog No. CSN21589

Synonyms: D-Vitamin E acetate;D-alpha-Tocopherolacetate;vitamin E acetate

α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. (+)-α-Tocopherol acetate is a lipid soluble anti-oxidant that protects cell membranes from oxidative damage in vitro.

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400-920-2911

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技术信息

生物活性

描述Alpha-tocopherol acetate (α-TOA), a synthetic vitamin E ester, attenuates electron flow through electron transport chain (ETC) which is probably associated with a moderate increase in mtROS in Mesenchymal Stromal Cells. α-TOA action results in enhancement of the proliferative capacity and maintenance of the differentiation potential of the mesenchymal stem and progenitor cells^[1]. ATA (Alpha-tocopherol acetat) and ALA (alpha lipoic acid) fed both independently and in combination had a positive effect on mitigating WB (wooden breast) severity microscopically as early as two weeks of age^[2]. alpha-tocopherol acetate is beneficial in xerosis, hyperkeratosis, asteatotic eczema, atopic dermatitis, superficial burns, cutaneous ulcers, onychoschizia and, in general, skin diseases in which an inflammatory process is activated^[3].
参考文献

[1] Loncaric D, Rodriguez L, Debeissat C, Touya N, Labat V, Villacreces A, Bouzier-Sore AK, Pasquet JM, de la Grange PB, Vlaski-Lafarge M, Pavlovic S, Ivanovic Z. α-Tocopherol Acetate Attenuates Mitochondrial Oxygen Consumption and Maintains Primitive Cells within Mesenchymal Stromal Cell Population. Stem Cell Rev Rep. 2021 Aug;17(4):1390-1405
[2] Wang J, Clark DL, Jacobi SK, Velleman SG. Alpha-tocopherol acetate and alpha lipoic acid may mitigate the development of wooden breast myopathy in broilers at an early age. Br Poult Sci. 2021 Oct;62(5):749-758
[3] Panin G, Strumia R, Ursini F. Topical alpha-tocopherol acetate in the bulk phase: eight years of experience in skin treatment. Ann N Y Acad Sci. 2004 Dec;1031:443-7

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.1153 mL
- 10.5766 mL
- 21.1532 mL
- 5 mM
- 0.4231 mL
- 2.1153 mL
- 4.2306 mL
- 10 mM
- 0.2115 mL
- 1.0577 mL
- 2.1153 mL

技术信息

CAS号

58-95-7

储存条件

粉末: Keep in dark place,Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C31H52O3

运输

蓝冰

分子量

472.74

别名

D-Vitamin E acetate;D-alpha-Tocopherolacetate;vitamin E acetate;α-生育酚醋酸酯

溶解度

Ethanol

100.0 mg/mL (211.5 mM) warming

动物实验配方

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D-α-Tocopherol acetate/生育酚乙酸酯 Catalog No. CSN21589

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