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CAS No.: 850876-88-9
Synonyms: ITMN-191;R7227;RO5190591
Danoprevir, a peptidomimetic, is an inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2 nM - 3.5 nM.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01579019 | Hepatitis C, Chronic | Phase 2 | Withdrawn | March 2014 | - |
NCT01185860 | Hepatitis C, Chronic | Phase 1 | Completed | - | France ... more >> Montpellier, France, 34094 New Zealand Christchurch, New Zealand, 8011 Grafton, New Zealand, 1010 Poland Warszawa, Poland, 01-201 Collapse << |
NCT01168856 | - | - | Terminated(This study was term... more >>inated due to the decrease in percentage of participants.) Collapse << | - | - |
实验方案
技术信息
CAS号 | 850876-88-9 | 储存条件 |
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分子式 | C35H46FN5O9S | 运输 | 蓝冰 | |||||
分子量 | 731.83 | 别名 | ITMN-191;R7227;RO5190591;RG7227;丹诺普韦 | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01579019 | Hepatitis C, Chronic | Phase 2 | Withdrawn | March 2014 | - |
NCT01185860 | Hepatitis C, Chronic | Phase 1 | Completed | - | France ... more >> Montpellier, France, 34094 New Zealand Christchurch, New Zealand, 8011 Grafton, New Zealand, 1010 Poland Warszawa, Poland, 01-201 Collapse << |
NCT01168856 | - | - | Terminated(This study was term... more >>inated due to the decrease in percentage of participants.) Collapse << | - | - |
NCT01168856 | - | - | Terminated(This study was term... more >>inated due to the decrease in percentage of participants.) Collapse << | - | - |
NCT00801255 | Hepatitis C, Chronic | Phase 1 | Completed | - | Australia ... more >> Adelaide, Australia, SA 5000 Heidelberg, Australia, 3084 Melbourne, Australia, 3181 New Zealand Christchurch, New Zealand, 8011 Grafton, New Zealand, 1150 Collapse << |
NCT00963885 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
NCT01483729 | Healthy Volunteer | Phase 1 | Completed | - | New Zealand ... more >> Christchurch, New Zealand, 8011 Collapse << |
NCT01278134 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
NCT03288636 | HCV | Phase 1 | Completed | - | China, Zhejiang ... more >> The first hospital of Zhejiang province Hangzhou, Zhejiang, China, 310003 Collapse << |
NCT01220947 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
NCT01398293 | Healthy Volunteer | Phase 1 | Completed | - | France ... more >> Strasbourg, France, 67064 Collapse << |
NCT01654211 | Healthy Volunteer | Phase 1 | Completed | - | Netherlands ... more >> Zuidlaren, Netherlands, 9471 GP Collapse << |
NCT01714154 | Healthy Volunteer | Phase 1 | Completed | - | Hungary ... more >> Balatonfuered, Hungary, 8230 Budapest, Hungary, 1076 Poland Warszawa, Poland, 01-201 Collapse << |
NCT01164488 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... more >> Lenexa, Kansas, United States, 66219 Collapse << |
NCT01331850 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
NCT03362814 | HCV | Phase 2 Phase 3 | Active, not recruiting | September 1, 2018 | China, Beijing ... more >> Peking University People's hospital Beijing, Beijing, China, 100044 Collapse << |
NCT01592305 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... more >> Lenexa, Kansas, United States, 66219 Collapse << |
NCT01392755 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... more >> Lenexa, Kansas, United States, 66219 Collapse << |
NCT01418274 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... more >> Lenexa, Kansas, United States, 66219 Collapse << |
NCT01389544 | Healthy Volunteer | Phase 1 | Completed | - | United States, California ... more >> Anaheim, California, United States, 92801 United States, Kansas Overland Park, Kansas, United States, 66211 Collapse << |
NCT01749150 | Hepatitis C, Chronic | Phase 2 | Completed | - | Korea, Republic of ... more >> Busan, Korea, Republic of, 614-735 Seoul, Korea, Republic of, 110-744 Seoul, Korea, Republic of, 120-752 Seoul, Korea, Republic of, 135-710 Taiwan Chiayi County, Taiwan, 61363 Kaohsiung, Taiwan, 807 Taichung, Taiwan, 40447 Taipei, Taiwan, 100 Taoyuan, Taiwan, 333 Yunlin County, Taiwan, 640 Thailand Bangkok, Thailand, 10330 Bangkok, Thailand, 10700 Chiang Mai, Thailand, 50200 Collapse << |
NCT01588002 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... more >> Lenexa, Kansas, United States, 66219 Collapse << |
NCT01185873 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... more >> Lenexa, Kansas, United States, 66219 Czech Republic Prague 8, Czech Republic, 180 00 Praha 7, Czech Republic, 170 00 Slovakia Bratislava, Slovakia, 831 01 Bratislava, Slovakia, 83305 Collapse << |
NCT01519336 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... more >> Lenexa, Kansas, United States, 66219 Collapse << |
NCT01592318 | Healthy Volunteer | Phase 1 | Completed | - | New Zealand ... more >> Christchurch, New Zealand, 8011 Collapse << |
NCT03020134 | Healthy | Phase 1 | Completed | - | - |
NCT01483742 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
NCT03020095 | Chronic Hepatitis C | Phase 2 | Completed | - | - |
NCT01514968 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... more >> Lenexa, Kansas, United States, 66219 Collapse << |
NCT03020004 | - | - | Completed | - | - |
NCT01531647 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... more >> Lenexa, Kansas, United States, 66219 Collapse << |
NCT03020082 | Chronic Hepatitis C | Phase 3 | Completed | - | - |
NCT03020004 | Chronic Hepatitis C | Phase 2 | Completed | - | - |
NCT03019991 | Healthy | Phase 1 | Completed | - | - |
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