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CAS No.: 890643-16-0
Synonyms: DC_05
DC_05 is a non-nucleoside DNMT1 inhibitor (IC50=10.3 μM) with low micromolar IC50 values and significant selectivity toward other AdoMet-dependent protein methyltransferases.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01360840 | Prostate Cancer Metastatic | Phase 2 | Completed | - | - |
NCT01360840 | - | - | Completed | - | - |
NCT02684006 | Renal Cell Cancer | Phase 3 | Active, not recruiting | April 30, 2021 | - |
实验方案
技术信息
CAS号 | 890643-16-0 | 储存条件 |
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分子式 | C25H25N3O | 运输 | 蓝冰 | |
分子量 | 383.49 | 别名 | DC_05 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01360840 | Prostate Cancer Metastatic | Phase 2 | Completed | - | - |
NCT01360840 | - | - | Completed | - | - |
NCT02684006 | Renal Cell Cancer | Phase 3 | Active, not recruiting | April 30, 2021 | - |
NCT01273064 | - | - | Terminated(Risk-benefit ratio) | - | - |
NCT00374569 | Gymnastics Injury, Motor Learn... more >>ing, Balance Collapse << | Early Phase 1 | Completed | - | United States, Texas ... more >> Carrick Institute for Graduate Studies Texas Dallas, Texas, United States, 75267 Collapse << |
NCT03053375 | Low Back Pain | Not Applicable | Recruiting | June 30, 2018 | United States, Connecticut ... more >> University of Bridgeport Recruiting Bridgeport, Connecticut, United States, 06604 Contact: Anthony J Lisi, DC alisi@bridgeport.edu Contact 203-576-4437 Collapse << |
NCT02667821 | - | - | Completed | - | - |
NCT02281266 | Curable Hepatitis B Virus-Rela... more >>ted Hepatocellular Carcinoma Collapse << | Phase 4 | Unknown | October 2018 | China, Shanghai ... more >> Zhongshan Hospital Shanghai, Shanghai, China, 200032 Collapse << |
NCT01273064 | Hepatitis C | Phase 2 | Terminated(Risk-benefit ratio) | - | - |
NCT02667821 | Vertebral Artery Dissection ... more >> Cerebrovascular Accident Stroke Collapse << | Not Applicable | Completed | - | Canada, Ontario ... more >> St. Joseph Healthcare, Research Imaging Institute Hamilton, Ontario, Canada, L8N 4A6 Collapse << |
NCT03737929 | Atrial Fibrillation | Not Applicable | Not yet recruiting | January 2022 | France ... more >> CHU Toulouse, Hôpital Rangueil Not yet recruiting Toulouse, France, 31059 Contact: Philippe Maury, MD 05 61 32 34 56 ext +33 maury.p@chu-toulouse.fr Contact: Anne Rollin, MD rollin.a@chu-toulouse.fr Principal Investigator: Philippe Maury, MD Sub-Investigator: Anne Rollin, MD Sub-Investigator: Bertrand Marcheix, MD Sub-Investigator: Etienne Grunenwald, MD Collapse << |
NCT00374049 | Prostate Cancer | Phase 1 | Completed | - | United States, Pennsylvania ... more >> Hillman Cancer Center Pittsburgh, Pennsylvania, United States, 15232 Collapse << |
NCT00179322 | - | - | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT00507117 | Obstructive Sleep Apnea | Phase 4 | Completed | - | United States, District of Col... more >>umbia Walter Reed Army Medical Center Washington DC, District of Columbia, United States, 20307 Collapse << |
NCT00887185 | Computer Simulation ... more >> Education Collapse << | Phase 2 | Completed | - | United States, Ohio ... more >> The Ohio State University Columbus, Ohio, United States, 43210 Collapse << |
NCT00342069 | - | - | Completed | - | United States, District of Col... more >>umbia Georgetown University Washington, D.C., District of Columbia, United States, 20007-2197 United States, Maryland Johns Hopkins University Baltimore, Maryland, United States, 21205 United States, Minnesota Abbott Northwestern Hospital Minneapolis, Minnesota, United States, 55407 United States, New York Genetic Counsel Program Binghamton, New York, United States, 13905 United States, Utah University of Utah Salt Lake City, Utah, United States, 84112 United States, Washington Eastside Maternal Fetal Medicine Bellevue, Washington, United States, 98004 Collapse << |
NCT00106782 | Dystonia Foca... more >>l Hand Dystonia FHD Collapse << | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT00479531 | Restless Legs Syndrome | Phase 3 | Completed | - | United States, District of Col... more >>umbia Christopher Lettieri MD Sleep Disorders Center, Walter Reed Army Medical Center, District of Columbia, United States, 20307-5001 Collapse << |
NCT00097162 | Amblyopia Ani... more >>sometropic Ambyopia Amblyopia, Suppression Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> National Eye Institute (NEI) Bethesda, Maryland, United States, 20892 Collapse << |
NCT00679887 | Shoulder Pain | Phase 1 Phase 2 | Completed | - | Canada, Quebec ... more >> 2930 Cote Richelieu Trois-Rivières, Quebec, Canada, G8Z3Y8 Collapse << |
NCT00269490 | - | - | Completed | - | United States, District of Col... more >>umbia Deployment Health Clinical Center, Walter Reed Army Medical Center Washington, District of Columbia, United States, 20307-8064 Collapse << |
NCT00766753 | Malignant Glioma | Phase 1 Phase 2 | Completed | - | United States, Pennsylvania ... more >> Hillman Cancer Center Pittsburgh, Pennsylvania, United States, 15232 Collapse << |
NCT00295581 | Plasmodium Falciparum ... more >> Plasmodium Vivax Malaria Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> Johns Hopkins School of Public Health Baltimore, Maryland, United States, 21205 National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT02573883 | Vulvar Lichen Sclerosus | Phase 3 | Recruiting | September 2019 | United States, District of Col... more >>umbia Medstar Washington Hospital Center Lafayette Office Recruiting Washington, District of Columbia, United States, 20010 Contact: Cheryl B Iglesia, MD 202-877-6526 Cheryl.Iglesia@medstar.net Contact: Patricia Tanjutco (202)877-6526 Joanna.l.peterson@medstar.net Sub-Investigator: Linda S Burkett, MD Sub-Investigator: Andrew I Sokol, MD Sub-Investigator: Amy J Park, MD Sub-Investigator: Robert E Gutman, MD Sub-Investigator: Lee A Richter, MD Collapse << |
NCT00766753 | - | - | Completed | - | - |
NCT03192358 | - | - | Recruiting | February 28, 2021 | United States, Florida ... more >> University of Florida Recruiting Gainesville, Florida, United States, 32611 Contact: Emily K Plowman, PhD 352-273-9215 eplowman@phhp.ufl.edu Contact: Kelby Magennis, MPH 352-273-8632 kmagennis@phhp.ufl.edu Collapse << |
NCT02151448 | Malignant Neoplasm of Pancreas... more >> Metastatic to Peritoneal Surface Malignant Peritoneal Mesothelioma Peritoneal Carcinomatosis Collapse << | Phase 1 Phase 2 | Active, not recruiting | December 2018 | United States, Pennsylvania ... more >> Hillman Cancer Center Pittsburgh, Pennsylvania, United States, 15232 Collapse << |
NCT00110175 | - | - | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT03496272 | - | - | Recruiting | June 30, 2021 | Korea, Republic of ... more >> Pusan National University Yangsan Hospital Recruiting Yangsan, Korea, Republic of, 50612 Contact: Yong Hyun Park, MD Collapse << |
NCT00280982 | Malignant Pleural Mesothelioma | Phase 1 | Completed | - | Netherlands ... more >> Department of Pulmonary Medicine Rotterdam, Zuid-Holland, Netherlands, 3015 GE Collapse << |
NCT00713050 | Ischemic Stroke | Not Applicable | Terminated(Protocol expired; P... more >>I retired) Collapse << | - | United States, California ... more >> Solodkin/Small Brain Circuits Laboratory Irvine, California, United States, 92697 University of California Irvine Irvine, California, United States, 92697 Collapse << |
NCT02382809 | Alveolar Osteitis | Phase 4 | Completed | - | Estonia ... more >> Tallinn, Estonia France Bordeaux, France Brest, France Dijon, France Lyon, France Metz, France Petit quevilly, France Pierre Benite, France Saint Maixent l'Ecole, France Strasbourg, France Toulouse, France Latvia Dauga Vpils, Latvia Liepaja, Latvia Riga, Latvia Valmiera, Latvia Lithuania Kaunas, Lithuania Klaipeda, Lithuania Vilnius, Lithuania Collapse << |
NCT00558051 | Metastatic Colorectal Cancer | Phase 1 | Completed | - | United States, Pennsylvania ... more >> University of Cancer Institute Pittsburgh, Pennsylvania, United States, 15232 Collapse << |
NCT00834002 | Acute Myeloid Leukemia (AML) | Phase 1 | Completed | - | Belgium ... more >> Antwerp University Hospital/Center for Cellular Therapy and Regenerative Medicine Edegem, Belgium, 2650 Collapse << |
NCT00117858 | Dementia | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
NCT03546361 | Carcinoma, Non-Small-Cell Lung | Phase 1 | Not yet recruiting | November 1, 2023 | - |
NCT00429884 | - | - | Unknown | - | Sweden ... more >> Heart Centre, Umeå University Hospital Recruiting Umeå, Sweden, 90185 Contact: Niklas Höglund, MD +46907852729 niklas.hoglund@vll.se Collapse << |
NCT02873494 | - | - | Completed | - | France ... more >> Lille University Hospital Lille, France, 59037 Collapse << |
NCT03185429 | Tumor Gastric ... more >> Tumor, Colorectal Collapse << | Not Applicable | Not yet recruiting | June 2019 | - |
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