CAS No.: 30197-14-9
Desoxyrhaponticin/脱氧土大黄苷 Catalog No. CSN19341
Synonyms: DC;DES;脱氧土大黄苷
Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Li P, Tian W, et al. Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan nutritional food Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells. Food Funct. 2014 Feb;5(2):251-6.
- [2] Li JM, Che CT, et al. Desoxyrhaponticin (3,5-dihydroxy-4'-methoxystilbene 3-O-beta-D-glucoside) inhibits glucose uptake in the intestine and kidney: In vitro and in vivo studies. J Pharmacol Exp Ther. 2007 Jan;320(1):38-46.
- [3] Li P, Tian W, Wang X, Ma X. Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan nutritional food Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells. Food Funct. 2014 Feb;5(2):251-6
- [4] Li JM, Che CT, Lau CB, Leung PS, Cheng CH. Desoxyrhaponticin (3,5-dihydroxy-4'-methoxystilbene 3-O-beta-D-glucoside) inhibits glucose uptake in the intestine and kidney: In vitro and in vivo studies. J Pharmacol Exp Ther. 2007 Jan;320(1):38-46
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 30197-14-9 | 储存条件 |
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| 分子式 | C21H24O8 | 运输 | 蓝冰 | |||
| 分子量 | 404.41 | 别名 | DC;DES;脱氧土大黄苷 | |||
| 溶解度 |
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动物实验配方 |
