CAS No.: 87205-99-0
Dihydrotanshinone I/二氢丹参酮I Catalog No. CSN16500
Synonyms: (-)-Dihydrotanshinone I;15;16-Dihydrotanshinone I
Dihydrotanshinone I, a natural product isolated and purified from the roots of Salvia miltiorrhiza Bge., exhibits dose-dependent inhibition towards HLM-catalyzed propofol glucuronidation. Dihydrotanshinone I showed inhibitory effect on PL(pro) with IC50 value of 4.9μM and less inhibitory effect on 3CLpro with IC50 value of 14.4μM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Cheung J, Beri V, Shiomi K, Rosenberry TL. Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination. J Mol Neurosci. 2014 Jul;53(3):506-10.
- [2] Cong M, Hu CM, et al. Cryptotanshinone and dihydrotanshinone I exhibit strong inhibition towards human liver microsome (HLM)-catalyzed propofol glucuronidation. Fitoterapia. 2013 Mar;85:109-13.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 87205-99-0 | 储存条件 |
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| 分子式 | C18H14O3 | 运输 | 蓝冰 | |
| 分子量 | 278.30 | 别名 | (-)-Dihydrotanshinone I;15;16-Dihydrotanshinone I;DHTS;二氢丹参酮 I;二氢丹参酮Ⅰ |
