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CAS No.: 3094-09-5
Synonyms: 去氧氟尿苷;Ro 21-9738;5-Fluoro-5'-deoxyuridine
Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.
生物活性
靶点 | Thymidine Phosphorylase IC50:0.62μM |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02494596 | - | - | Completed | - | - |
NCT00842244 | Stomach Neoplasms ... more >> Advanced Gastric Cancer Collapse << | Phase 1 | Completed | - | Japan ... more >> Pfizer Investigational Site Kashiwa, Chiba, Japan Pfizer Investigational Site Yufu-city, Oita, Japan Korea, Republic of Pfizer Investigational Site Goyang-si, Gyeonggi-do, Korea, Republic of, 410-769 Pfizer Investigational Site Seongnam-si, Gyeonggi-do, Korea, Republic of, 463-707 Pfizer Investigational Site Seoul, Korea, Republic of, 110-744 Collapse << |
NCT00925769 | Pancreatic Cancer | Phase 1 | Completed | - | Austria ... more >> Vienna, Austria, 1100 Wien, Austria, 1130 Collapse << |
实验方案
技术信息
CAS号 | 3094-09-5 | 储存条件 |
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分子式 | C9H11FN2O5 | 运输 | 蓝冰 | |||||||
分子量 | 246.19 | 别名 | 去氧氟尿苷;Ro 21-9738;5-Fluoro-5'-deoxyuridine;5'-DFUR | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02494596 | - | - | Completed | - | - |
NCT00842244 | Stomach Neoplasms ... more >> Advanced Gastric Cancer Collapse << | Phase 1 | Completed | - | Japan ... more >> Pfizer Investigational Site Kashiwa, Chiba, Japan Pfizer Investigational Site Yufu-city, Oita, Japan Korea, Republic of Pfizer Investigational Site Goyang-si, Gyeonggi-do, Korea, Republic of, 410-769 Pfizer Investigational Site Seongnam-si, Gyeonggi-do, Korea, Republic of, 463-707 Pfizer Investigational Site Seoul, Korea, Republic of, 110-744 Collapse << |
NCT00925769 | Pancreatic Cancer | Phase 1 | Completed | - | Austria ... more >> Vienna, Austria, 1100 Wien, Austria, 1130 Collapse << |
NCT02494596 | Solid Tumor | Phase 1 | Completed | - | Spain ... more >> Barcelona, Spain, 08036 United Kingdom Manchester, United Kingdom, M20 4BX Collapse << |
NCT00925769 | - | - | Completed | - | - |
NCT00842244 | - | - | Completed | - | - |
NCT00555620 | Stomach Neoplasms | Phase 1 | Completed | - | Korea, Republic of ... more >> Pfizer Investigational Site Seongnam-si, Gyeonggi-do, Korea, Republic of, 463-707 Pfizer Investigational Site Goyang, Gyeonggi, Korea, Republic of, 410-769 Pfizer Investigational Site Seoul, Korea, Republic of, 110-744 Collapse << |
NCT00662025 | Advanced/Metastatic Breast Can... more >>cer Collapse << | Phase 2 | Completed | - | Japan ... more >> Pfizer Investigational Site Anjo-city, Aichi, Japan Pfizer Investigational Site Nagoya, Aichi, Japan Pfizer Investigational Site Okazaki-City, Aichi, Japan Pfizer Investigational Site Toyoake, Aichi, Japan Pfizer Investigational Site Matsuyama-shi, Ehime, Japan Pfizer Investigational Site Kure, Hiroshima, Japan Pfizer Investigational Site Morioka, Iwate, Japan Pfizer Investigational Site Yokohama, Kanagawa, Japan Pfizer Investigational Site Sakai, Osaka, Japan Pfizer Investigational Site Bunkyo-ku, Tokyo, Japan Pfizer Investigational Site Koto-ku, Tokyo, Japan Pfizer Investigational Site Chiba, Japan Pfizer Investigational Site Fukuoka, Japan Pfizer Investigational Site Kagoshima, Japan Pfizer Investigational Site Kyoto, Japan Pfizer Investigational Site Niigata, Japan Pfizer Investigational Site Osaka, Japan Collapse << |
NCT00555620 | - | - | Completed | - | - |
NCT00532948 | Glioma | Phase 1 | Completed | - | United States, California ... more >> San Francisco, California, United States, 94143-0780 United States, District of Columbia Washington, District of Columbia, United States, 20010 United States, Illinois Chicago, Illinois, United States, 60614 United States, Massachusetts Boston, Massachusetts, United States, 02115-6084 United States, North Carolina Durham, North Carolina, United States, 27710 United States, Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Pittsburgh, Pennsylvania, United States, 15261 United States, Texas Houston, Texas, United States, 77030 United States, Washington Seattle, Washington, United States, 98105 Collapse << |
NCT00169000 | Metastatic Breast Cancer | Phase 1 | Completed | - | United States, New Hampshire ... more >> Norris Cotton Cancer Center Lebanon, New Hampshire, United States, 03756 Collapse << |
NCT02368860 | Pancreatic Cancer | Phase 1 | Recruiting | June 2019 | Singapore ... more >> National Cancer Centre Recruiting Singapore, Singapore, 169610 Contact: Lanying Wang 64368267 nctwly@nccs.com.sg Collapse << |
NCT00812864 | Breast Cancer ... more >> Colorectal Cancer Collapse << | Phase 4 | Completed | - | France ... more >> CHU Limoges Limoges Cedex, Province, France, 87042 Collapse << |
NCT00858429 | Liver Cancer ... more >>Metastatic Cancer Collapse << | Phase 1 | Active, not recruiting | December 2018 | United States, Illinois ... more >> Northwestern University Chicago, Illinois, United States, 60611 Collapse << |
NCT00353262 | Colorectal Cancer | Phase 1 | Completed | - | Canada, Ontario ... more >> Hamilton, Ontario, Canada, L8V 5C2 Ottawa, Ontario, Canada, K1H 8L6 Toronto, Ontario, Canada, M5G 2M9 Collapse << |
NCT03465202 | Breast Cancer ... more >> Colorectal Cancer Collapse << | Phase 4 | Not yet recruiting | November 2019 | - |
NCT00662025 | - | - | Completed | - | - |
NCT00296335 | Stomach Cancer | Phase 3 | Completed | - | Korea, Republic of ... more >> Asan Medical Center Seoul, Korea, Republic of, 138-736 Collapse << |
NCT00296322 | Stomach Cancer | Phase 3 | Completed | - | Korea, Republic of ... more >> Asan Medical Center Seoul, Korea, Republic of, 138-736 Collapse << |
NCT00353262 | - | - | Completed | - | - |
NCT00296322 | - | - | Completed | - | - |
NCT00532948 | - | - | Completed | - | - |
NCT00296335 | - | - | Completed | - | - |
NCT01401075 | Gastric Cancer | Phase 4 | Completed | - | Korea, Republic of ... more >> ASAN Medical Center Seoul, Korea, Republic of, 138-736 Collapse << |
靶点 | Description | IC50 |
---|---|---|
Thymidine Phosphorylase | IC50:0.62μM |
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