CAS No.: 289483-69-8
E7820 Catalog No. CSN18950
Synonyms: ER68203-00
E7820 is an angiogenesis inhibitor by suppressing integrin a2, a cell adhesion molecule expressed on endothelial cells.
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生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00078637 Neoplasms Lym... more >>phoma, Malignant Collapse << Phase 1 Completed - United States, Texas ... more >> San Antonio, Texas, United States Collapse << NCT01133990 Colorectal Cancer Phase 1 Phase 2 Completed - - NCT00309179 Advanced Colorectal Cancer Phase 2 Completed - United States, California ... more >> Los Angeles, California, United States United States, Florida Miami, Florida, United States Canada, Alberta Edmonton, Alberta, Canada Collapse << - 更多
- 参考文献
- [1] Ito K, Semba T, et al. Enhanced anti-angiogenic effect of E7820 in combination with erlotinib in epidermal growth factor receptor-tyrosine kinase inhibitor-resistant non-small-cell lung cancer xenograft models. Cancer Sci. 2014 Aug;105(8):1023-31.
- [2] Keizer RJ, Funahashi Y, et al. Evaluation of α2-integrin expression as a biomarker for tumor growth inhibition for the investigational integrin inhibitor E7820 in preclinical and clinical studies. AAPS J. 2011 Jun;13(2):230-9.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 289483-69-8 | 储存条件 |
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| 分子式 | C17H12N4O2S | 运输 | 蓝冰 | |||||
| 分子量 | 336.37 | 别名 | ER68203-00 | |||||
| 溶解度 |
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动物实验配方 |
