CAS No.: 512-64-1
Echinomycin/Echinomycin游离态 Catalog No. CSN20491
Synonyms: Quinomycin A;NSC-13502;Antibiotic A 654I
Echinomycin is a highly potent and selective HIF-1α inhibitor (IC50 = 29.4 pM) which selectively inhibits HIF-1 binding to the VEGF promoter without affecting the binding of AP-1 or NF-κB.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Kwon TG, Zhao X, et al. Physical and functional interactions between Runx2 and HIF-1α induce vascular endothelial growth factor gene expression. J Cell Biochem. 2011 Dec;112(12):3582-93.
- [2] Kong D, Park EJ, et al. Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Res. 2005 Oct 1;65(19):9047-55.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 512-64-1 | 储存条件 |
|
|
| 分子式 | C51H64N12O12S2 | 运输 | 蓝冰 | |
| 分子量 | 1101.26 | 别名 | Quinomycin A;NSC-13502;Antibiotic A 654I;NSC 526417;SK 302B |
