|2-乙氧-4-乙酰胺苯甲酯|CsnPharm

CAS No.: 59-06-3

Ethopabate/乙氧酰胺苯甲酯 Catalog No. CSN20805

Synonyms: 乙氧酰胺苯甲酯;Ethyl pabate

Ethopabate is an arylamide veterinary drug used in the prophylaxis and treatment of coccidiosis in chickens.

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400-920-2911

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技术信息

生物活性

描述Ethopabate is an antiprotozoal agent which has been widely used to treat and prevent coccidiosis in chickens^[1]. Treatment with toltrazuril, sulphaquinoxaline/pyrimethamine and amprolium/ethopabate prevented mortality in chickens infected with field isolates of Eimeria tenella. Amprolium/ethopabate was the most effective drug in reducing lesions caused by the parasites^[2]. Average recoveries from poultry samples fortified with 10, 15, and 20 microg/kg levels of ethopabate were 100-105%^[3]. Recoveries of ethopabate added to chicken tissues at levels of 0.01 and 0.05 ppm were 87.8 and 92.7%, respectively. The detection limit was 100 pg for ethopabate standard, and 0.5 ppb in chicken tissues^[4].
参考文献

[1] Nasr JJ, Shalan S. Spectrofluorimetric analysis of ethopabate in veterinary formulations with application to residue determination in chicken muscles and liver. Luminescence. 2014;29(8):1188‐1193
[2] Chapman HD. Chemotherapy of caecal coccidiosis: efficacy of toltrazuril, sulphaquinoxaline/pyrimethamine and amprolium/ethopabate, given in drinking water, against field isolates of Eimeria tenella. Res Vet Sci. 1989;46(3):419‐420
[3] Granja RH, Niño AM, Zucchetti RA, Niño RE, Salerno AG. Validation of a high-performance liquid chromatographic method with UV detection for the determination of ethopabate residues in poultry liver. J AOAC Int. 2008;91(6):1483‐1487
[4] Nagata T, Saeki M, Nakazawa H, Fujita M, Takabatake E. Sensitive determination of ethopabate residues in chicken tissues by liquid chromatography with fluorometric detection. J Assoc Off Anal Chem. 1985;68(1):27‐28

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.2149 mL
- 21.0747 mL
- 42.1493 mL
- 5 mM
- 0.8430 mL
- 4.2149 mL
- 8.4299 mL
- 10 mM
- 0.4215 mL
- 2.1075 mL
- 4.2149 mL

技术信息

CAS号

59-06-3

储存条件

粉末: Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C12H15NO4

运输

蓝冰

分子量

237.25

别名

乙氧酰胺苯甲酯;Ethyl pabate

溶解度

DMSO	118.0 mg/mL (497.4 mM)
Water	insoluble

动物实验配方

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Ethopabate/乙氧酰胺苯甲酯 Catalog No. CSN20805

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