CAS No.: 1215085-92-9
GLPG0492 Catalog No. CSN17572
Synonyms: DT-200
GLPG0492 is a selective androgen receptor modulator and exhibits anabolic activity on muscle, strongly dissociated from the androgenic activity on prostate after oral dosing.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01130818 Healthy Phase 1 Completed - Belgium ... more >> SGS Stuivenberg Antwerp, Belgium Collapse << NCT01538420 Healthy Phase 1 Completed - Belgium ... more >> SGS Stuivenberg Antwerp, Belgium Collapse << NCT01397370 Healthy Phase 1 Completed - Germany ... more >> Parexel Early Phase Clinical Unit Berlin, Germany, 14050 Collapse << - 参考文献
- [1] Cozzoli A, Capogrosso RF, et al. GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy. Pharmacol Res. 2013 Jun;72:9-24.
- [2] Nique F, Hebbe S, et al. Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator. J Med Chem. 2012 Oct 11;55(19):8236-47.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1215085-92-9 | 储存条件 |
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| 分子式 | C19H14F3N3O3 | 运输 | 蓝冰 | |
| 分子量 | 389.33 | 别名 | DT-200 |
