CAS No.: 173529-10-7
HMN-176 Catalog No. CSN19103
HMN-176 is the active derivative of HMN-214 which can alter the cellular spatial orientation of Plk1.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] DiMaio MA, Mikhailov A, et al. The small organic compound HMN-176 delays satisfaction of the spindle assembly checkpoint by inhibiting centrosome-dependent microtubule nucleation. Mol Cancer Ther. 2009 Mar;8(3):592-601.
- [2] Medina-Gundrum L, Cerna C, et al. Investigation of HMN-176 anticancer activity in human tumor specimens in vitro and the effects of HMN-176 on differential gene expression. Invest New Drugs. 2005 Jan;23(1):3-9.
- [3] Takagi M, Honmura T, et al. In vivo antitumor activity of a novel sulfonamide, HMN-214, against human tumor xenografts in mice and the spectrum of cytotoxicity of its active metabolite, HMN-176. Invest New Drugs. 2003 Nov;21(4):387-99.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 173529-10-7 | 储存条件 |
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| 分子式 | C20H18N2O4S | 运输 | 蓝冰 | |||||||
| 分子量 | 382.43 | 别名 | ||||||||
| 溶解度 |
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动物实验配方 |
