CAS No.: 501364-82-5
INO-1001 Catalog No. CSN26730
Synonyms: IN01001
INO-1001 is an isoindolinone derivative and potent inhibitor of the nuclear enzyme poly (ADP-ribose) polymerase (PARP) with chemosensitization and radiosensitization properties. INO-1001 inhibits PARP, which may result in inhibition of tumor cell DNA repair mechanisms and, so, tumor cell resistance to chemotherapy and radiation therapy. PARP enzymes are activated by DNA breaks and have been implicated in the repair of DNA single-strand breaks (SSB). NOTE: as of 7/29/2016, many vendors are selling INO-1001 with wrong structure (3-aminobenzamide, CAS# 3544-24-9)
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| CAS号 | 501364-82-5 | 储存条件 |
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| 分子式 | C23H25N3O4S | 运输 | 蓝冰 | |
| 分子量 | 439.53 | 别名 | IN01001 |
