CAS No.: 1012104-68-5
IRAK inhibitor 4 Catalog No. CSN17391
IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor.
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生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00708240 Obsessive Compulsive Disorder Phase 4 Unknown December 2010 Canada, Ontario ... more >> University of Ottawa Institute of Mental Health Research Recruiting Ottawa, Ontario, Canada, K1Z7K4 Contact: Zul Merali, PhD 613-722-6521 ext 6551 zul.merali@rohcg.on.ca Principal Investigator: Martine F. Flament, MD Collapse << NCT02996500 Rheumatoid Arthritis Phase 2 Completed - - - 参考文献
- [1] Marinho FV, Fahel JS, et al. Lack of IL-1 Receptor-Associated Kinase-4 Leads to Defective Th1 Cell Responses and Renders Mice Susceptible to Mycobacterial Infection. J Immunol. 2016 Sep 1;197(5):1852-63.
- [2] Talreja J, Talwar H, et al. Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1β and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells. J Immunol. 2016 Aug 15;197(4):1368-78.
实验方案
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技术信息
| CAS号 | 1012104-68-5 | 储存条件 |
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| 分子式 | C33H35F3N6O3 | 运输 | 蓝冰 | |
| 分子量 | 620.66 | 别名 |
