CAS No.: 138402-11-6
Irbesartan/伊贝沙坦 Catalog No. CSN12537
Synonyms: SR-47436;BMS-186295;Avapro
Irbesartan is a selective and competitive nonpeptide angiotensin II antagonist with antihypertensive activity.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
靶点 Angiotensin Receptor 1
IC50:1.3nM- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00741702 Hypertension ... more >>Diabetes Mellitus Collapse << Not Applicable Completed - - NCT01195818 Sickle Cell Disease Not Applicable Completed - France ... more >> Centre de la Drépanocytose, Service de Médecine Interne. Hôpital Tenon, 4 Rue de la Chine Paris, France, 75020 Collapse << NCT01715207 Marfan Syndrome Phase 3 Completed - Korea, Republic of ... more >> Samsung Medical Center Seoul, Korea, Republic of, 135-710 Collapse << - 更多
- 参考文献
- [1] Kawano H, Cody RJ, et al. Angiotensin II enhances integrin and alpha-actinin expression in adult rat cardiac fibroblasts. Hypertension. 2000 Jan;35(1 Pt 2):273-9.
- [2] Bernhart CA, Perreaut PM, et al. A new series of imidazolones: highly specific and potent nonpeptide AT1 angiotensin II receptor antagonists. J Med Chem. 1993 Oct 29;36(22):3371-80.
- [3] Gialama F, Maniadakis N. Comprehensive overview: efficacy, tolerability, and cost-effectiveness of irbesartan. Vasc Health Risk Manag. 2013;9:575-92. doi: 10.2147/VHRM.S50831. Epub 2013 Oct 7. PMID: 24124375; PMCID: PMC3794869.
- [4] Shahin NN, Abdelkader NF, Safar MM. A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling. Sci Rep. 2018 Mar 9;8(1):4280. doi: 10.1038/s41598-018-22727-6. PMID: 29523851; PMCID: PMC5844881.
- [5] Boccellino M, Di Domenico M, Donniacuo M, Bitti G, Gritti G, Ambrosio P, Quagliuolo L, Rinaldi B. AT1-receptor blockade: Protective effects of irbesartan in cardiomyocytes under hypoxic stress. PLoS One. 2018 Oct 24;13(10):e0202297. doi: 10.1371/journal.pone.0202297. PMID: 30356256; PMCID: PMC6200178.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 138402-11-6 | 储存条件 |
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| 分子式 | C25H28N6O | 运输 | 蓝冰 | |||||||||||
| 分子量 | 428.53 | 别名 | SR-47436;BMS-186295;Avapro;Aprovel;Karvea;厄贝沙坦 | |||||||||||
| 溶解度 |
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动物实验配方 |
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| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT00741702 | Hypertension ... more >>Diabetes Mellitus Collapse << | Not Applicable | Completed | - | - |
| NCT01195818 | Sickle Cell Disease | Not Applicable | Completed | - | France ... more >> Centre de la Drépanocytose, Service de Médecine Interne. Hôpital Tenon, 4 Rue de la Chine Paris, France, 75020 Collapse << |
| NCT01715207 | Marfan Syndrome | Phase 3 | Completed | - | Korea, Republic of ... more >> Samsung Medical Center Seoul, Korea, Republic of, 135-710 Collapse << |
| NCT01715207 | - | - | Completed | - | - |
| NCT02973035 | Hypertension | Phase 4 | Recruiting | June 2019 | Korea, Republic of ... more >> Busan Baik Hospital Recruiting Busan, Korea, Republic of Contact: Jeong-Suk Seo, M.D. orifilter@hanmail.net Busan University Hospital Recruiting Busan, Korea, Republic of Contact: Yong-Hyun Park nadroj@chol.com Chungnam University Hospital Recruiting Daejeon, Korea, Republic of Contact: Jae-Hyung Park, M.D. jaehpark@cnuh.co.kr Asan Medical Center Recruiting Seoul, Korea, Republic of Contact: Duk-Hyun Kang, M.D. dhkang@amc.seoul.kr Collapse << |
| NCT00361023 | Type 2 Diabetes ... more >> Diabetic Nephropathy Collapse << | Not Applicable | Completed | - | - |
| NCT01805362 | Chronic Kidney Disease | Not Applicable | Unknown | February 2017 | France ... more >> Department of Nephrology, Nice University Hospital Recruiting Nice, France, 06000 Contact: vincent Esnault, MD esnault.v@chu-nice.fr Principal Investigator: Vincent Esnault, MD Collapse << |
| NCT00212901 | Diabetic Kidney Disease | Not Applicable | Completed | - | Canada, Ontario ... more >> The Ottawa Hospital Ottawa, Ontario, Canada, K1H 7W9 Collapse << |
| NCT00794963 | Metabolic Syndrome | Not Applicable | Terminated(Difficulty recruiti... more >>ng) Collapse << | - | United States, New York ... more >> Zucker Hillside Hospital Glen Oaks, New York, United States, 11004 Collapse << |
| NCT00794963 | - | - | Terminated(Difficulty recruiti... more >>ng) Collapse << | - | - |
| NCT00180024 | Healthy Subjects | Not Applicable | Completed | - | Germany ... more >> Institute of Clinical Pharmacology, Medical Faculty, University of Technology Dresden, Germany, 01307 Collapse << |
| NCT00657059 | IgA Nephropathy | Phase 3 | Active, not recruiting | April 2019 | China, Guangdong ... more >> The 1st Affiliated Hospital, Sun Yet-sen University Guangzhou, Guangdong, China, 510080 Collapse << |
| NCT01500590 | Diabetes Hype... more >>rtensive Disease Collapse << | Phase 4 | Active, not recruiting | August 2019 | China ... more >> Hospital Authority, HKEC, FM&PHC Hong Kong, China Collapse << |
| NCT02644486 | Obesity and Glomerulopathy | Not Applicable | Terminated(difficulty in enrol... more >>lment) Collapse << | - | China, Jiangsu ... more >> Research Institute of Nephrology, Jinling Hospital, Nanjing University School of Medicine Nanjing, Jiangsu, China, 210002 Collapse << |
| NCT02380625 | Ebola Virus Disease | Phase 1 Phase 2 | Unknown | March 2016 | - |
| NCT00106561 | Kidney Disease ... more >> Diabetic Nephropathy Glomerulonephritis Proteinuria Collapse << | Phase 2 Phase 3 | Completed | - | Australia, Victoria ... more >> Department of Nephrology, The Royal Melbourne Hospital Melbourne, Victoria, Australia, 3050 Collapse << |
| NCT00224549 | Hypertension | Phase 4 | Completed | - | France ... more >> Investigation Clinical Center European Georges Pompidou Hospital Paris, Ile de France, France, 75015 Collapse << |
| NCT00005010 | End-Stage Renal Disease ... more >> Chronic Allograft Nephropathy Collapse << | Phase 3 | Completed | - | United States, Maryland ... more >> Ilene Blechman-Krom Rockville, Maryland, United States, 20850 Collapse << |
| NCT03016832 | Diabetic Kidney Disease | Early Phase 1 | Unknown | December 2018 | China, Jiangsu ... more >> Jiangsu Province Hospital of TCM Recruiting Nanjing, Jiangsu, China Contact: Wei Sun +86 13505199801 jssunwei@163.com Collapse << |
| NCT01968759 | Chronic Kidney Disease | Phase 2 | Completed | - | Italy ... more >> Clinical Research Center for Rare Diseases Ranica, Bergamo, Italy, 24020 Azienda Ospedaliera "Bianchi-Melacrino-Morelli" c/o Ospedali Riuniti U.O. Nefrologia, Dialisi e Trapianto Reggio Calabria, Italy Collapse << |
| NCT00635232 | - | - | Completed | - | - |
| NCT00742066 | Hypertension ... more >>Insulin Resistance Microcirculation Collapse << | Not Applicable | Unknown | July 2009 | Netherlands ... more >> University Hospital Maastricht Maastricht, P.O. Box 5800, Netherlands, 6202 AZ Collapse << |
| NCT00249873 | Atrial Fibrillation ... more >> Vascular Risk Collapse << | Phase 3 | Completed | - | - |
| NCT00243178 | Atrial Fibrillation ... more >> Vascular Risk Collapse << | Phase 3 | Terminated | - | - |
| NCT00635232 | Hypertension | Phase 2 | Completed | - | - |
| NCT02721342 | - | - | Recruiting | March 2019 | Italy ... more >> Centro di Ricerche Cliniche per le Malattie Rare Aldo e Cele Daccò Recruiting Ranica, Bergamo, Italy, 24020 Contact: Erica Daina, MD erica.daina@marionegri.it Ospedale Morgagni - Pierantoni - U.O. Nefrologia e Dialisi Recruiting Forlì, Forli', Italy, 47011 Contact: Giovanni Mosconi, MD giovanni.mosconi@ausl.fo.it Asl 6 Sanluri-P.O. Nostra Signora di Bonaria - U.O. Nefrologia e Dialisi Recruiting San Gavino- Monreale, Medio Campidano - VS, Italy, 09037 Contact: Maria Cristina Mereu, MD mariacristina.mereu@asl6sanluri.it Ospedale C.G. Mazzoni Zona 13 ASUR Marche - U.O. Nefrologia e Dialisi Recruiting Ascoli Piceno, Italy, 63100 Contact: Mauro Ragaiolo, MD m.ragaiolo@asl13.marche.it AORN Moscati - Avellino - U.O. Nefrologia e Dialisi Recruiting Avellino, Italy, 83100 Contact: Walter De Simone, MD wadesimone@aosgmoscati.av.it A.O. Papa Giovanni XXIII - U.O. Nefrologia e Dialisi Recruiting Bergamo, Italy, 20147 Contact: Piero Ruggenenti, MD pruggenenti@hpg23.it A.O. Papa Giovanni XXIII Bergamo - U.O. Diabetologia Recruiting Bergamo, Italy, 20147 Contact: Roberto Trevisan, MD rtrevisan@hpg23.it Azienda Ospedaliera G. Brotzu - U.O. Nefrologia e Dialisi Recruiting Cagliari, Italy, 09100 Contact: Antonello Pani, MD antonellopani@aob.it Ospedale Campo di Marte - USL 2 - U.O. Nefrologia Recruiting Lucca, Italy, 55100 Contact: Alberto Rosati, MD arosati@usl2.toscana.it ARNAS Ospedale Civico Di Cristina Benfratelli - U.O. Nefrologia e Dialisi Recruiting Palermo, Italy, 90127 Contact: Carlo Giammarresi, MD cgiammer@tin.it Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone, Università degli Studi di Palermo - Dipartimento Malattie Cardiovascolari e Nefrourologiche - U.O. Tecniche Dialitiche Recruiting Palermo, Italy, 90129 Contact: Maurizio Li Vecchi, MD livecchi@unipa.it Azienda Ospedaliera Universitaria Pisana - U.O. Nefrologia e Dialisi 2 Recruiting Pisa, Italy, 56126 Contact: Giuliano Barsotti, MD g.barsotti@med.unipi.it Ospedale di Circolo Fondazione Macchi - U.O. Nefrologia e Dialisi Recruiting Varese, Italy, 21100 Contact: Gian Maria Frattini, MD gianmaria.frattini@ospedale.varese.it Collapse << |
| NCT00343551 | Essential Hypertension | Phase 3 | Completed | - | Germany ... more >> Investigative Centers, Germany Switzerland Novartis Pharmaceuticals Basel, Switzerland Collapse << |
| NCT01360710 | Abdominal Obesity ... more >> Hypertension Collapse << | Phase 4 | Unknown | - | Australia, Victoria ... more >> BakerIDI Heart and Diabetes Institute Recruiting Prahran, Victoria, Australia, 3004 Contact: Markus Schlaich markus.schlaich@bakeridi.edu.au Collapse << |
| NCT01109212 | Diabetic Nephropathy | Phase 2 | Completed | - | Italy ... more >> The Mario Negri Institute for Pharmacological Research- Clinical Research Center for Rare Diseases Ranica, Bergamo, Italy, 24020 Azienda Ospedaliera di Treviglio-Caravaggio - Unità Operativa Malattie Metaboliche e Diabetologia Treviglio, Bergamo, Italy, 24047 Azienda Ospedaliera OO.RR. Bergamo - Unità Operativa Diabetologia Bergamo, Italy, 24128 IRCCS Fondazione Centro S. Raffaele del Monte Tabor- Unità Operativa Medicina Generale Milano, Italy, 20132 Ist. Patologia Medica e metodologia Clinica - Università di Sassari Sassari, Italy, 7100 Slovenia University Medical Center Dpt Endocrinology Diabetes and Metabolic Diseases- Diabetology Unit Ljubljana, Slovenia, 1000 Collapse << |
| NCT03493685 | Focal Segmental Glomeruloscler... more >>osis Collapse << | Phase 3 | Recruiting | December 2022 | - |
| NCT01519297 | Preeclampsia ... more >>Pregnancy Induced Hypertension Collapse << | Not Applicable | Recruiting | June 2018 | United States, Massachusetts ... more >> Brigham and Women's Hospital Recruiting Boston, Massachusetts, United States, 02115 Collapse << |
| NCT03762850 | Immunoglobulin A Nephropathy | Phase 3 | Not yet recruiting | April 2023 | - |
| NCT00249873 | - | - | Completed | - | - |
| NCT01613118 | Focal Segmental Glomeruloscler... more >>osis Collapse << | Phase 2 | Active, not recruiting | August 2021 | - |
| NCT00500604 | Hypertension | Phase 4 | Completed | - | Egypt ... more >> Sanofi-Aventis Administrative Office Cairo, Egypt Hong Kong Sanofi-Aventis Administrative Office Hong Kong, Hong Kong India Sanofi-Aventis Administrative Office Mumbai, India Indonesia Sanofi-Aventis Administrative Office Jakarta, Indonesia Korea, Republic of Sanofi-Aventis Administrative Office Seoul, Korea, Republic of Malaysia Sanofi-Aventis Administrative Office Kuala Lumpur, Malaysia Morocco Sanofi-Aventis Administrative Office Casablanca, Morocco Pakistan Sanofi-Aventis Administrative Office Karachi, Pakistan Philippines Sanofi-Aventis Administrative Office Makati City, Philippines Singapore Sanofi-Aventis Administrative Office Singapore, Singapore Taiwan Sanofi-Aventis Administrative Office Taipei, Taiwan Thailand Sanofi-Aventis Administrative Office Bangkok, Thailand Tunisia Sanofi-Aventis Administrative Office Megrine, Tunisia Vietnam Sanofi-Aventis Administrative Office Ho Chi Minh City, Vietnam Collapse << |
| NCT01238705 | Hypertension ... more >>Sexual Dysfunction Collapse << | Phase 4 | Unknown | November 2010 | China, Gansu ... more >> The Second Hospital of Lanzhou University Recruiting Lanzhou, Gansu, China, 730000 Contact: Ruixin Ma, Doctor +86 13893102690 mrxdr@sina.com Contact: Jing Yu, Professor +86 13893607559 yujing2304@126.com Principal Investigator: Jing Yu, Professor Sub-Investigator: Ruixin Ma, Doctor Collapse << |
| NCT02597361 | Ehlers-Danlos Syndrome, Vascul... more >>ar Type Collapse << | Phase 3 | Recruiting | April 2020 | France ... more >> CHU DE BORDEAUX - Hopital Saint Andre Recruiting Bordeaux, France, 33075 Contact: Joel CONSTANS, MD,PHD +33 5 56 79 57 16 joel.constans@chu-bordeaux.fr CHU DE LYON - Hopital Femme Mere Enfant Recruiting Bron, France, 69500 Contact: Sophie DUPUIS-GIROD, MD,PHD +33 4 27 85 65 24 sophie.dupuis-girod@chu-lyon.fr CHU DE CAEN - Hopital Cote de Nacre Recruiting Caen, France, 14033 Contact: Damien LANEELLE, MD,PHD +33 2 31 06 53 27 laneelle-d@chu-caen.fr CHU DE TOURS - Hopital Trousseau Not yet recruiting Chambray-les-Tours, France, 37044 Contact: Gabriela GEORGESCOU, MD +33 2 47 47 46 25 g.georgescou@chu-tours.fr CHU DE GRENOBLE - Hopital Albert Michallon Recruiting Grenoble, France, 38043 Contact: Christophe SEINTURIER, MD,PHD +33 4 76 76 89 60 cseinturier@chu-grenoble.fr CHU DE GRENOBLE - Hopital Couple Enfant Not yet recruiting Grenoble, France, 38043 Contact: Pierre-Simon JOUK, MD,PHD +33 7 76 76 72 85 psjouk@chu-grenoble.fr CHRU DE LILLE - Hopital Claude Huriez Recruiting Lille, France, 59000 Contact: Marc LAMBERT, MD +33 3 20 44 42 96 marc.lambert@chru-lille.fr CHU DE LYON - Hopital Edouard Herriot Not yet recruiting Lyon, France, 69003 Contact: Jacques NINET, MD,PHD +33 4 72 11 75 71 jacques.ninet@chu-lyon.fr AP-HM - Hopital de la Timone Recruiting Marseille, France, 13385 Contact: Laurence BAL-THEOLEYRE, MD +33 4 91 38 81 20 laurence.bal@ap-hm.fr CHU DE MONTPELLIER - Hopital Saint Eloi Recruiting Montpellier, France, 34295 Contact: Isabelle QUERE, MD,PHD +33 67 33 70 25 i-quere@chu-montpellier.fr CHU DE NANTES - Hopital Hotel-Dieu Not yet recruiting Nantes, France, 44300 Contact: Marc-Antoine PISTORIUS, MD +33 2 40 08 33 34 marc.pistorius@chu-nantes.fr AP-HP - Hopital Europeen Georges-Pompidou Recruiting Paris, France, 75015 Contact: Xavier JEUNEMAITRE, MD,PHD +33 1 56 09 38 80 xavier.jeunemaitre@aphp.fr Contact: Michael FRANK, MD +33 1 56 09 50 40 michael.frank@aphp.fr CHU DE TOULOUSE - Hopital Purpan Not yet recruiting Toulouse, France, 31059 Contact: Sophie JULIA, MD +33 5 61 77 90 55 julia.s@chu-toulouse.fr CHU DE TOULOUSE - Hopital Rangueil Recruiting Toulouse, France, 31059 Contact: Alessandra BURA-RIVIERE, MD,PHD +33 5 61 32 24 38 bura-riviere.a@chu-toulouse.fr CHRU DE NANCY - Institut Lorrain du Coeur et des Vaisseaux Recruiting Vandoeuvre-les-Nancy, France, 54500 Contact: Denis WAHL, MD,PHD +33 3 83 15 36 14 d.wahl@chu.nancy.fr Collapse << |
| NCT00219115 | Hypertension | Phase 3 | Completed | - | United States, New Jersey ... more >> Novartis Pharmaceuticals East Hanover, New Jersey, United States, 07936 Germany Investigative Centers, Germany Collapse << |
| NCT00264212 | Hypertension | Phase 4 | Completed | - | Chile ... more >> Sanofi-Aventis Santiago, Chile China Sanofi-Aventis Shangai, China Indonesia Sanofi-Aventis Jakarta, Indonesia Korea, Republic of Sanofi-Aventis Seoul, Korea, Republic of Mexico Sanofi-Aventis Mexico, Mexico Philippines Sanofi-Aventis Manila, Philippines Taiwan Sanofi-Aventis Taipei, Taiwan Thailand Sanofi-Aventis Bangkok, Thailand Collapse << |
| NCT03006796 | - | - | Recruiting | June 2019 | Russian Federation ... more >> City Hospital №5 Recruiting Moscow, Russian Federation, 107015 Contact: Elena Y Shupenina, PhD +74992684459 Collapse << |
| NCT01949233 | Marfan Syndrome | Phase 2 | Unknown | December 2017 | United Kingdom ... more >> John Radcliffe Hospital Recruiting Oxford, Oxfordshire, United Kingdom, OX3 9DU Sub-Investigator: Edward Blair, MBChB MRCP Sub-Investigator: Paul Wordsworth, MB FRCP University of Oxford Recruiting Oxford, Oxfordshire, United Kingdom, OX3 9DU Sub-Investigator: Alex Pitcher, DPhil, MA, BM BCh, MRCP Sub-Investigator: Andrew Lewis, MB BS MRes MRCP Sub-Investigator: Hayley Harvey Sub-Investigator: Stefan Neubauer, MD FRCP FACC FMedSci Sub-Investigator: Paul Leeson Sub-Investigator: Jacqueline Birks Collapse << |
| NCT01992796 | Severe Sepsis | Phase 3 | Unknown | January 2017 | Italy ... more >> Università di Salerno Not yet recruiting Salerno, Italy Contact: Ornella Piazza Principal Investigator: Ornella Piazza Collapse << |
| NCT00660309 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | United States, Massachusetts ... more >> Novartis Investigator Site Boston, Massachusetts, United States, 02115 Collapse << |
| NCT00350038 | Hypertension ... more >>Dyslipidemia Collapse << | Phase 4 | Completed | - | Hungary ... more >> Sanofi-aventis Budapest, Hungary Collapse << |
| NCT01082835 | - | - | Unknown | August 2010 | China, Beijing ... more >> Beijing Medical University ,Dongzhimen Hospital Not yet recruiting Beijing, Beijing, China Contact: Weixing Lu 0086-013601067938 weixinglu918@sina.com Beijing Medical University,Dongfang Hospital Not yet recruiting Beijing, Beijing, China Contact: Qian Lin 0086-013910565673 dfluyao@126.com China Academy of Chinese Medical Sciences,Guang'anmen Hospital Not yet recruiting Beijing, Beijing, China Contact: Qiang Zhou 0086-015101016416 tiantianlanzhouqiang@126.com Chinese Academy of Medical Sciences Fu Wai Cardiovascular Hospital Not yet recruiting Beijing, Beijing, China Contact: Jianfeng Huang 0086-010-88396403 jianfhuang918@sina.com Capital University of Medical, Anzhen Hospital Not yet recruiting Beijng, Beijing, China Contact: Zhenqiu Yu 0086-010-64456577 yuzhenqiu@yahoo.com.cn Collapse << |
| NCT00171080 | Hypertension | Phase 3 | Completed | - | Germany ... more >> Investigative Centers, Germany Switzerland Novartis Pharmaceuticals Basel, Switzerland Collapse << |
| NCT00950066 | Hypertension | Phase 2 | Completed | - | India ... more >> Sanofi-Aventis Administrative Office Mumbai, India Korea, Republic of Sanofi-Aventis Administrative Office Seoul, Korea, Republic of Philippines Sanofi-Aventis Administrative Office Makati City, Philippines Taiwan Sanofi-Aventis Administrative Office Taipei, Taiwan Collapse << |
| NCT00185055 | Healthy | Phase 4 | Completed | - | - |
| NCT00154024 | Healthy Subjects | Not Applicable | Completed | - | Germany ... more >> Institute of Clinical Pharmacology, Medical Faculty, University of Technology Dresden, Germany, 01307 Collapse << |
| NCT00561964 | Hypertension | Phase 3 | Completed | - | - |
| NCT00708344 | Hypertension | Phase 4 | Completed | - | Algeria ... more >> Sanofi-Aventis Administrative Office Algiers, Algeria Argentina Sanofi-Aventis Administrative Office Buenos Aires, Argentina Brazil Sanofi-Aventis Administrative Office Sao Paulo, Brazil Colombia Sanofi-Aventis Administrative Office Bogota, Colombia Ecuador Sanofi-Aventis Administrative Office Quito, Ecuador Egypt Sanofi-Aventis Administrative Office Cairo, Egypt Guatemala Sanofi-Aventis Administrative Office Guatemala City, Guatemala Lebanon Sanofi-Aventis Administrative Office Beirut, Lebanon Mexico Sanofi-Aventis Administrative Office Col. Coyoacan, Mexico Morocco Sanofi-Aventis Administrative Office Casablanca, Morocco Panama Sanofi-Aventis Administrative Office Panama, Panama Peru Sanofi-Aventis Administrative Office Lima, Peru Saudi Arabia Sanofi-Aventis Administrative Office Jeddah, Saudi Arabia Tunisia Sanofi-Aventis Administrative Office Megrine, Tunisia United Arab Emirates Sanofi-Aventis Administrative Office Dubaï, United Arab Emirates Venezuela Sanofi-Aventis Administrative Office Caracas, Venezuela Collapse << |
| NCT00125645 | Myocardial Infarction | Phase 4 | Completed | - | Denmark ... more >> Kardiologisk Klinik, Centralsygehuset Esbjerg/Varde Esbjerg, Denmark, 6700 Collapse << |
| NCT01442987 | Hypertension ... more >>Hyperlipidemia Collapse << | Phase 3 | Completed | - | Korea, Republic of ... more >> 16 institutions including Seoul National University Hospital Seoul, Korea, Republic of Collapse << |
| NCT00660309 | - | - | Completed | - | - |
| NCT03627715 | Diabetic Kidney Disease | Phase 2 | Recruiting | October 2019 | Australia, New South Wales ... more >> Renal Research Recruiting Gosford, New South Wales, Australia Contact: Simon Rogers Liverpool Hospital Recruiting Liverpool, New South Wales, Australia, 2170 Contact: Michael Suranyi Royal North Shore Hospital Recruiting St Leonards, New South Wales, Australia, 2065 Contact: Carol Pollock Westmead Hospital Recruiting Westmead, New South Wales, Australia, 2145 Contact: Richard Phoon Australia, Queensland Sunshine Coast University Hospital Not yet recruiting Birtinya, Queensland, Australia, 4575 Contact: Nicholas Gray Princess Alexandra Hospital Recruiting Woolloongabba, Queensland, Australia, 4102 Contact: David Mudge Australia, Victoria Boxhill Hospital Recruiting Box Hill, Victoria, Australia, 3128 Contact: Matthew Roberts Austin Hospital Recruiting Heidelberg, Victoria, Australia, 3084 Contact: David Power Sunshine Hospital Recruiting Melbourne, Victoria, Australia, 3021 Contact: Craig Nelson Epworth Hospital Recruiting Richmond, Victoria, Australia, 3121 Contact: Ian Fraser Collapse << |
| NCT00095238 | Congestive Heart Failure | Phase 3 | Completed | - | - |
| NCT00265642 | Hepatitis C, Chronic | Phase 3 | Completed | - | France ... more >> CHU Angers, Service d'hépato-gastroentérologie Angers, France, 49933 cedex 09 Collapse << |
| NCT00335673 | Hypertension | Phase 4 | Completed | - | Egypt ... more >> Sanofi-Aventis Administrative Office Cairo, Egypt Collapse << |
| NCT03649152 | Focal Segmental Glomeruloscler... more >>osis Collapse << | Phase 2 | Recruiting | December 2019 | Australia, New South Wales ... more >> Renal Research Recruiting Gosford, New South Wales, Australia, 2250 Contact: Simon Roger Liverpool Hospital Recruiting Liverpool, New South Wales, Australia, 2170 Contact: Michael Suranyi Royal North Shore Hospital Recruiting St Leonards, New South Wales, Australia, 2065 Contact: Carol Pollock Westmead Recruiting Westmead, New South Wales, Australia, 2145 Contact: Richard Phoon Australia, Queensland Sunshine Coast University Hospital Recruiting Birtinya, Queensland, Australia, 4575 Contact: Nicholas Gray Princess Alexandra Hospital Recruiting Woolloongabba, Queensland, Australia, 4102 Contact: David Mudge Australia, Victoria Box Hill Hospital Recruiting Box Hill, Victoria, Australia, 3128 Contact: Matthew Roberts Austion Hospital Recruiting Heidelberg, Victoria, Australia, 3084 Contact: David Power Sunshine Hospital Recruiting Melbourne, Victoria, Australia, 3021 Contact: Craig Nelson Epworth Hospital Recruiting Richmond, Victoria, Australia, 3121 Contact: Ian Fraser Collapse << |
| NCT00095238 | - | - | Completed | - | - |
| NCT00347087 | Chronic Heart Failure | Phase 4 | Completed | - | Germany ... more >> Applied Cachexia Research, Cardiology Dept. Charite Medical School, Virchow Klinikum Berlin, Germany Collapse << |
| NCT01625494 | Hypertension | Phase 3 | Completed | - | Russian Federation ... more >> Sanofi-Aventis Administrative Office Moscow, Russian Federation Collapse << |
| NCT00296218 | Myocardial Ischemia ... more >> Hypertension Collapse << | Phase 3 | Completed | - | United States, New Jersey ... more >> Sanofi-Aventis Bridgewater, New Jersey, United States Belgium Sanofi-Aventis Brussels, Belgium Canada Sanofi-Aventis Laval, Canada France Sanofi-Aventis Paris, France Germany Sanofi-Aventis Berlin, Germany Hungary Sanofi-Aventis Budapest, Hungary Italy Sanofi-Aventis Milan, Italy Netherlands Sanofi-Aventis Gouda, Netherlands Spain Sanofi-Aventis Barcelona, Spain Switzerland Sanofi-Aventis Meyrin, Switzerland United Kingdom Sanofi-Aventis Guildford, United Kingdom Collapse << |
| NCT00670566 | Hypertension | Phase 4 | Completed | - | China ... more >> Sanofi-Aventis Administrative Office Shanghai, China Collapse << |
| NCT02148991 | - | - | Completed | - | Greece ... more >> Georgios Gennimatas General State Hospital Athens, Holargos, Greece, 11527 Georgios Gennimatas General State Hospital Athens, Greece, 10682 Collapse << |
| NCT00225667 | Atrial Fibrillation ... more >> Hypertension Collapse << | Phase 3 | Unknown | - | Canada, Ontario ... more >> Population Health Research Institute of McMaster University Not yet recruiting Hamilton, Ontario, Canada, L8L 2X2 Contact: Ellison J. Themeles, MSc. 905-527-4322 ext 44713 themelese@ccc.mcmaster.ca Principal Investigator: Stuart J. Connolly, MD Collapse << |
| NCT00529750 | Hypertension | Phase 4 | Completed | - | - |
| NCT00283036 | Hypertension | Phase 4 | Completed | - | Algeria ... more >> Sanofi-Aventis Alger, Algeria Collapse << |
| NCT00562809 | Hypertension | Phase 4 | Completed | - | United States, New Jersey ... more >> Sanofi-Aventis Bridgewater, New Jersey, United States, 08807 Collapse << |
| NCT01858610 | Healthy | Not Applicable | Completed | - | Egypt ... more >> Pharmaceutics Department, Faculty of Pharmacy, Damanhour University Damanhour, Egypt Collapse << |
| NCT00320879 | Type 2 Diabetes ... more >> Microalbuminuria Collapse << | Phase 4 | Completed | - | Denmark ... more >> Steno Diabetes Center Gentofte, Copenhagen, Denmark, 2820 Collapse << |
| NCT00464880 | Diabetes Type 2 | Phase 1 Phase 2 | Completed | - | Denmark ... more >> Novartis Gentofte, Denmark, 2820 Collapse << |
| NCT00362037 | Hypertension | Phase 4 | Completed | - | Egypt ... more >> Sanofi-Aventis Administrative Office Cairo, Egypt Collapse << |
| NCT00317915 | Type 2 Diabetes ... more >> Microalbuminuria Hypertension Collapse << | Phase 3 | Completed | - | - |
| NCT00095550 | Hypertension | Phase 3 | Completed | - | - |
| NCT00152698 | Hypercholesterolemia | Phase 3 | Completed | - | Germany ... more >> CRC, Medizinsiche Klinik 4, Nephrology and Hypertension, University of Erlangen-Nürnberg Erlangen, Bavaria, Germany, 91054 Collapse << |
| NCT00110422 | Metabolic Syndrome ... more >> Hypertension Collapse << | Phase 4 | Completed | - | France ... more >> Local Institution Angers, France Local Institution Nantes, France Local Institution Tierce, France Germany Local Institution Hannover, Germany Local Institution Muenchen, Germany Local Institution Ornbau, Germany Local Institution Rotenburg An De Fluda, Germany Local Institution Tuebingen, Germany Local Institution Villingen-Schwenningen, Germany Italy Local Institution Ancona, Italy Local Institution Chieti Scalo, Italy Local Institution Pisa, Italy Local Institution Ravenna, Italy Local Institution Sassari, Italy Norway Local Institution Oslo, Norway Local Institution Snaroya, Norway Russian Federation Local Institution Moscow, Russian Federation Local Institution Saratov, Russian Federation Local Institution St. Petersburg, Russian Federation Local Institution Yaroslavl, Russian Federation Spain Local Institution A Coruna, Spain Local Institution Barcelona, Spain Local Institution Granada, Spain Local Institution Sevilla, Spain Local Institution Zaragoza, Spain Collapse << |
| NCT00362258 | Hypertension | Phase 4 | Completed | - | Egypt ... more >> Sanofi-Aventis Administrative Office Cairo, Egypt Collapse << |
| NCT00847834 | Hypertension | Phase 4 | Completed | - | China ... more >> Sanofi aventis administrative office Beijing, China Collapse << |
| NCT00095290 | Albuminuria | Phase 4 | Completed | - | - |
| NCT00334581 | Hypertension | Phase 4 | Completed | - | China ... more >> Sanofi-Aventis Administrative Office Shanghai, China Collapse << |
| NCT00956644 | Hypertension | Phase 3 | Completed | - | - |
| NCT00389168 | - | - | Completed | - | - |
| NCT00517322 | Left Atrial Volume ... more >> Hypertensive Heart Disease Antihypertensive Drugs Diastolic Function Renin Angiotensin System Collapse << | Phase 4 | Unknown | August 2010 | Italy ... more >> University of Insubria-Department of Clinical Medicine Recruiting Varese, Italy, 21100 Contact: anna maria grandi, MD +39+332 278594 amgrandi@libero.it Contact: anna maria grandi, MD +39 + 332 278594 amgrandi@libero.it Sub-Investigator: andrea maria maresca, MD Sub-Investigator: andrea bertolini, MD Sub-Investigator: monica gianni, MD Sub-Investigator: eleonora nicolini, MD Collapse << |
| NCT00389168 | Hypertension | Phase 2 Phase 3 | Completed | - | Sweden ... more >> Karolinska Institutet, Daprtment of Clinical Sciences, Danderyd Hospital, Cardiovascular Research Laboratory Stockholm, Sweden, SE-182 88 Collapse << |
| NCT00249795 | Atrial Fibrillation ... more >> Cardiovascular Disease Collapse << | Phase 3 | Completed | - | - |
| NCT00791830 | Kidney Failure, Chronic | Phase 3 | Completed | - | Denmark ... more >> Department of Nephrology, Aarhus University, Aalborg Aalborg, Denmark, 9000 Department of Nephrology, Aarhus University Hospital, Skejby Aarhus N, Denmark, 8200 Department of Medicine, Fredericia Hospital Fredericia, Denmark, 7000 Haemodialysis unit, Horsens Hospital Horsens, Denmark, 8700 Hemodialysis Unit, Randers Hospital Randers, Denmark, 8600 Department of Medicine M, Viborg Hospital Viborg, Denmark, 8800 Collapse << |
| NCT00263003 | Hypertension | Phase 3 | Completed | - | Taiwan ... more >> Sanofi-Aventis Taipei, Taiwan Collapse << |
| NCT01712126 | Hypertension | Not Applicable | Completed | - | United States, Texas ... more >> Worldwide Clinical Trials Drug Development Solutions (formerly CEDRA Clinical Research) San Antonio, Texas, United States, 78217 Collapse << |
| NCT00249795 | - | - | Completed | - | - |
| NCT00564187 | Hypertension | Phase 4 | Completed | - | Tunisia ... more >> Sanofi-Aventis Megrine, Tunisia Collapse << |
| NCT01712100 | Hypertension | Not Applicable | Completed | - | United States, Texas ... more >> Worldwide Clinical Trials Drug Development Solutions (formerly CEDRA Clinical Research) San Antonio, Texas, United States, 78217 Collapse << |
| NCT00095394 | Hypertension | Phase 3 | Completed | - | - |
| NCT01712113 | Hypertension | Not Applicable | Completed | - | United States, Texas ... more >> Worldwide Clinical Trials Drug Development Solutions (formerly CEDRA Clinical Research) San Antonio, Texas, United States, 78217 Collapse << |
| NCT00957554 | Hypertension | Phase 3 | Completed | - | - |
| NCT00265967 | Hypertension | Phase 4 | Completed | - | Turkey ... more >> Sanofi-Aventis Istanbul, Turkey Collapse << |
| NCT00613496 | Persistent Atrial Fibrillation | Phase 4 | Unknown | May 2010 | Germany ... more >> University Hospital Magdeburg; Div. of Cardiology Recruiting Magdeburg, Germany, 39120 Contact: Veronika Raetzel 0049 391 6701 veronika.raetzel@medizin.uni-magdeburg.de Collapse << |
| NCT00443612 | Hypertension | Phase 4 | Completed | - | Taiwan ... more >> Sanofi-Aventis Taipei, Taiwan Collapse << |
| NCT01712139 | Hypertension | Not Applicable | Completed | - | United States, Texas ... more >> Worldwide Clinical Trials Drug Development Solutions (formerly CEDRA Clinical Research) San Antonio, Texas, United States, 78217 Collapse << |
| NCT01825850 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Asan Medical Center Seoul, Korea, Republic of Collapse << |
| NCT00987662 | Obesity Hyper... more >>tension Collapse << | Phase 4 | Withdrawn(no funding) | January 2014 | Greece ... more >> Hypertension-24h ABPM Center Papageorgiou Hospital Thessaloniki, Greece Collapse << |
| NCT02842359 | Type 2 Diabetes Mellitus | Phase 4 | Completed | - | Korea, Republic of ... more >> Korea Seoul, Korea, Republic of Collapse << |
| NCT03147677 | Type 2 Diabetic Nephropathy | Phase 4 | Recruiting | December 2018 | China, Hunan ... more >> The Third Xiangya Hospital of Central South University Recruiting Changsha, Hunan, China, 410000 Contact: Hao Zhang, Doctor +86-13975806919 zhanghaoliaoqing@163.com Hunan Chenzhou NO.1 People's Hospital Recruiting Chenzhou, Hunan, China, 423000 Contact: Xiangpin Liao, bachelor +81-13507359887 13507359887@139.com Hunan Yiyang Central Hospital Recruiting Yiyang, Hunan, China, 413000 Contact: Xiaohua Deng, bachelor +81-13707370981 yoyotyz@126.com Collapse << |
| NCT00352560 | Atrial Fibrillation | Phase 3 | Completed | - | Spain ... more >> Local Institution Madrid, Spain, 28040 Local Institution Madrid, Spain, 28046 Local Institution Madrid, Spain, 28905 Collapse << |
| NCT03476603 | - | - | Recruiting | October 2026 | Norway ... more >> St. Olavs University Hospital Recruiting Trondheim, Norway Contact: Magnus Strømmen, MSc Collapse << |
| NCT01447797 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Korea University Anam Hospital Seoul, Korea, Republic of Collapse << |
| NCT00549133 | Hypertension ... more >>Diabetes Mellitus Type 2 Collapse << | Phase 4 | Completed | - | Turkey ... more >> Sanofi-Aventis Istanbul, Turkey Collapse << |
| NCT02386293 | Hypertension ... more >>Obesity Stress, Psychological Blood Pressure Collapse << | Phase 2 | Recruiting | May 2019 | United States, Georgia ... more >> Augusta University Recruiting Augusta, Georgia, United States, 30912 Contact: Kimberly Norland 706-721-1755 knorland@augusta.edu Contact: Sandra Young-Mayes, BS 7067211755 syoungmayes@augusta.edu Principal Investigator: Gregory A Harshfield, PhD Sub-Investigator: Ryan A Harris, PhD Sub-Investigator: Yanbin Dong, MD, PhD Collapse << |
| 靶点 | Description | IC50 |
|---|---|---|
| Angiotensin Receptor 1 | IC50:1.3nM |
