|(1R,3R,4S,5R)-3,5-双(((E)-3-(3,4-二羟基苯基)丙烯酰)氧基)-1,4-二羟基-3-甲基环己烷甲酸|CsnPharm

CAS No.: 2450-53-5

Isochlorogenic acid A/异绿原酸A Catalog No. CSN19338

Synonyms: 3,5-Dicaffeoylquinic acid;3,5-CQA;Isochlorogenic Acid A

Isochlorogenic Acid A is a natural phenolic compound with antioxidant, anti-inflammatory and antiviral biological activities.

规格	价格	促销价格	库存	数量

400-920-2911

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技术信息

生物活性

描述Isochlorogenic acid A is widely present in fruits, vegetables and herbal medicines, and is characterized by anti-inflammatory, hepatoprotective and antiviral properties^[3]. The effects of oxidant stress, pulmonary edema and inflammation factors induced by LPS were inhibited by isochlorogenic acid A. Levels of lung active markers and inflammation factors induced by LPS were reversed by isochlorogenic acid A. Isochlorogenic acid A inhibited the cell apoptosis induced by LPS. The protein expressions of Nf-κB/NLRP3 signaling pathway induced by LPS were inhibited by isochlorogenic acid A^[4]. Isochlorogenic acid A, also called 3,5-dicaffeoylquinic acid (3,5-diCQA), is a widespread phenolic compound in the plant. 3,5-diCQA upregulated intracellular melanin production in a time- and dose-dependent manner. Tyrosinase (TYR) activity was also increased after treatment with 3,5-diCQA in a dose-dependent manner. Expressions of TYR, TYR-related protein 1, TYR-related protein 2, and microphthalmia-associated transcription factor were upregulated in a dose-dependent manner after 48 h of treatment with 3,5-diCQA. Moreover, 3,5-diCQA increased the content of β-catenin in cell cytoplasm and nucleus by reducing the content of phosphorylated β-catenin (p-β-catenin)^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.9363 mL
- 9.6815 mL
- 19.3630 mL
- 5 mM
- 0.3873 mL
- 1.9363 mL
- 3.8726 mL
- 10 mM
- 0.1936 mL
- 0.9681 mL
- 1.9363 mL

技术信息

CAS号

2450-53-5

储存条件

粉末: Sealed in dry,Store in freezer, under -20°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C26H26O12

运输

蓝冰

分子量

530.48

别名

3,5-Dicaffeoylquinic acid;3,5-CQA;Isochlorogenic Acid A;3,5-DCQA;异绿原酸 A;3,5-O-二咖啡酰基奎宁酸

溶解度

DMSO	205.0 mg/mL (386.4 mM)
Water	insoluble

动物实验配方

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