CAS No.: 481-39-0
Juglone/胡桃醌 Catalog No. CSN19714
Synonyms: 5-Hydroxy-1,4-naphthalenedione;Regianin;5-Hydroxy-1,4-naphthoquinone
Juglone significantly inhibits the proliferation and induce the apoptosis of SiHa cells and Caski cells, stimulates suicidal erythrocyte death or eryptosis at least in part by upregulation of ceramide abundance, energy depletion and activation of PKC, and prevents high-fat diet-induced liver injury and nerve inflammation in mice through inhibition of inflammatory cytokine secretion, NF-kappa B activation and endotoxin production. It's a natural product isolated and purified from the barks of Juglans regia L..
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Peng X, Nie Y, et al. Juglone prevents metabolic endotoxemia-induced hepatitis and neuroinflammation via suppressing TLR4/NF-κB signaling pathway in high-fat diet rats. Biochem Biophys Res Commun. 2015 Jul 3;462(3):245-50.
- [2] Calabro S, Alzoubi K, et al. Enhanced eryptosis following juglone exposure. Basic Clin Pharmacol Toxicol. 2015 Jun;116(6):460-7.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 481-39-0 | 储存条件 |
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| 分子式 | C10H6O3 | 运输 | 蓝冰 | |||
| 分子量 | 174.15 | 别名 | 5-Hydroxy-1,4-naphthalenedione;Regianin;5-Hydroxy-1,4-naphthoquinone;NSC 34266;Akhnot;NSC-153189;NSC-622948;胡桃醌 | |||
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动物实验配方 |
