CAS No.: 1610954-97-6
LX2761 Catalog No. CSN19739
LX2761 is a locally acting SGLT1 inhibitor that is highly potent in vitro and delays intestinal glucose absorption in vivo to improve glycemic control. LX2761 was designed to remain in the intestine after oral delivery to inhibit SGLT1 locally without affecting the SGLT1/2 mechanism in the kidney.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Goodwin NC, Ding ZM, et al. Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes. J Med Chem. 2017 Jan 17.
- [2] Powell DR, Smith MG, et al. LX2761, a Sodium/Glucose Cotransporter 1 Inhibitor Restricted to the Intestine, Improves Glycemic Control in Mice. J Pharmacol Exp Ther. 2017 Apr 25. pii: jpet.117.240820.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1610954-97-6 | 储存条件 |
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| 分子式 | C32H47N3O6S | 运输 | 蓝冰 | |
| 分子量 | 601.80 | 别名 |
