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CAS No.: 1192189-69-7
LX7101 is a potent inhibitor of LIMK and ROCK2 with IC50 values of 24, 1.6 and 10 nM for LIMK1, LIMK2 and ROCK2, respectively and also inhibits PKA with an IC50 less than 1 nM.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01528111 | Primary Open-angle Glaucoma ... more >> Ocular Hypertension Collapse << | Phase 1 Phase 2 | Completed | - | United States, Georgia ... more >> Lexicon Investigational Site Morrow, Georgia, United States, 30260 United States, Tennessee Lexicon Investigational Site Memphis, Tennessee, United States, 38119 United States, Texas Lexicon Investigational Site Austin, Texas, United States, 78731 Lexicon Investigational Site Houston, Texas, United States, 77025 Lexicon Investigational Site San Antonio, Texas, United States, 78209 Collapse << |
实验方案
技术信息
CAS号 | 1192189-69-7 | 储存条件 |
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分子式 | C23H29N7O3 | 运输 | 蓝冰 | |
分子量 | 451.52 | 别名 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01528111 | Primary Open-angle Glaucoma ... more >> Ocular Hypertension Collapse << | Phase 1 Phase 2 | Completed | - | United States, Georgia ... more >> Lexicon Investigational Site Morrow, Georgia, United States, 30260 United States, Tennessee Lexicon Investigational Site Memphis, Tennessee, United States, 38119 United States, Texas Lexicon Investigational Site Austin, Texas, United States, 78731 Lexicon Investigational Site Houston, Texas, United States, 77025 Lexicon Investigational Site San Antonio, Texas, United States, 78209 Collapse << |
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