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CAS No.: 176161-24-3
Synonyms: 1263W94;BW1263W94;GW257406X
Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus (EBV).
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00002373 | Cytomegalovirus Infections ... more >> HIV Infections Collapse << | Phase 1 | Completed | - | United States, California ... more >> Univ of California/ San Francisco / Dept of Medicine San Francisco, California, United States, 94110 Dr Jacob Lalezari San Francisco, California, United States, 94115 Collapse << |
NCT00411645 | Cytomegalovirus Infections | Phase 3 | Completed | - | - |
NCT00497796 | Cytomegalovirus Infections | Phase 3 | Completed | - | - |
实验方案
技术信息
CAS号 | 176161-24-3 | 储存条件 |
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分子式 | C15H19Cl2N3O4 | 运输 | 蓝冰 | |
分子量 | 376.24 | 别名 | 1263W94;BW1263W94;GW257406X;Benzimidavir;GW-1263;SHP-620;VP-41263;马立巴韦 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00002373 | Cytomegalovirus Infections ... more >> HIV Infections Collapse << | Phase 1 | Completed | - | United States, California ... more >> Univ of California/ San Francisco / Dept of Medicine San Francisco, California, United States, 94110 Dr Jacob Lalezari San Francisco, California, United States, 94115 Collapse << |
NCT00411645 | Cytomegalovirus Infections | Phase 3 | Completed | - | - |
NCT00497796 | Cytomegalovirus Infections | Phase 3 | Completed | - | - |
NCT00411645 | - | - | Completed | - | - |
NCT02927067 | Cytomegalovirus (CMV) | Phase 3 | Recruiting | August 13, 2021 | - |
NCT00223925 | Cytomegalovirus Infection | Phase 2 | Completed | - | United States, California ... more >> City of Hope Medical Center Duarte, California, United States UCLA Medical Center Los Angeles, California, United States United States, Illinois Loyola University Maywood, Illinois, United States United States, Massachusetts Tufts-New England Medical Center Boston, Massachusetts, United States United States, Michigan Wayne State Medical Center Detroit, Michigan, United States United States, Minnesota University of Minnesota Minneapolis, Minnesota, United States United States, Missouri Washington University School of Medicine St. Louis, Missouri, United States United States, New York Memorial Sloan-Kettering Cancer Center New York, New York, United States United States, North Carolina Duke Medical Center Durham, North Carolina, United States United States, Texas Baylor University Medical Center Dallas, Texas, United States MD Anderson Cancer Center Houston, Texas, United States United States, Utah University of Utah Salt Lake City, Utah, United States United States, Washington Fred Hutchinson Cancer Research Center Seattle, Washington, United States Collapse << |
NCT00497796 | - | - | Completed | - | - |
NCT02931539 | Cytomegalovirus (CMV) | Phase 3 | Recruiting | May 6, 2019 | - |
NCT01611974 | - | - | Completed | - | - |
NCT02775240 | Cytomegalovirus (CMV) | Phase 1 | Completed | - | United States, Florida ... more >> Clinical Pharmacology of Miami, Inc. Miami, Florida, United States, 33014 Collapse << |
NCT01611974 | Cytomegalovirus Infections | Phase 2 | Completed | - | - |
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