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CAS No.: 790299-79-5
Synonyms: AB1010;Masican;Masiviera
Masitinib is an inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00831922 | Rheumatoid Arthritis | Phase 2 | Completed | - | - |
NCT00831974 | Mastocytosis | Phase 2 | Completed | - | - |
NCT01045577 | Psoriasis | Phase 2 | Completed | - | - |
实验方案
技术信息
CAS号 | 790299-79-5 | 储存条件 |
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分子式 | C28H30N6OS | 运输 | 蓝冰 | |
分子量 | 498.64 | 别名 | AB1010;Masican;Masiviera;Masivet;马赛替尼 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00831922 | Rheumatoid Arthritis | Phase 2 | Completed | - | - |
NCT00831974 | Mastocytosis | Phase 2 | Completed | - | - |
NCT01045577 | Psoriasis | Phase 2 | Completed | - | - |
NCT01433497 | Multiple Sclerosis, Secondary ... more >>Progressive Multiple Sclerosis, Primary Progressive Multiple Sclerosis, Relapse Free Collapse << | Phase 3 | Active, not recruiting | March 2019 | Spain ... more >> Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08041 Collapse << |
NCT01450488 | Multiple Sclerosis | Phase 2 | Completed | - | - |
NCT00842270 | Asthma | Phase 2 | Completed | - | - |
NCT00866138 | Multiple Myeloma | Phase 2 | Completed | - | France ... more >> Hopital Saint Louis Paris, France Collapse << |
NCT02605044 | Metastatic Colorectal Cancer | Phase 3 | Terminated(Sponsor decision ba... more >>sed on portfolio prioritization) Collapse << | - | France ... more >> Hopital Europeen George Pomipidou, Hepato-Gastro-enterologie, 20 rue Leblanc Paris, France, 75 Singapore National Cancer Center, 11 Hospital Drive Singapore, Singapore, 169610 United Kingdom Hammersmith Hospital, Department of Cancer Medicine, Imperial College Healthcare Trust, Du Cane Road London, United Kingdom, W12 0HS Collapse << |
NCT00789633 | Pancreatic Cancer | Phase 3 | Completed | - | - |
NCT02490488 | Ovarian Cancer | Phase 2 Phase 3 | Recruiting | December 2020 | France ... more >> Institut Sainte Catherine Recruiting Avignon, France, 84000 Contact: Julien GRENIER, MD Collapse << |
NCT00812240 | Gastrointestinal Stromal Tumor... more >>s Collapse << | Phase 3 | Terminated(Sponsor decision ba... more >>sed on portfolio prioritization) Collapse << | - | - |
NCT01266369 | Mastocytosis | Phase 2 | Completed | - | - |
NCT01506336 | Gastro Intestinal Stromal Tumo... more >>r Collapse << | Phase 2 | Completed | - | France ... more >> Institute Gustave Roussy (IGR) Villejuif, France, 94815 Collapse << |
NCT03127267 | Amyotrophic Lateral Sclerosis | Phase 3 | Not yet recruiting | May 2024 | - |
NCT02009423 | Gastro-Intestinal Stromal Tumo... more >>ur Collapse << | Phase 3 | Terminated(Sponsor decision ba... more >>sed on portfolio prioritization) Collapse << | - | - |
NCT01449162 | Asthma | Phase 3 | Active, not recruiting | March 2019 | Hungary ... more >> University of Debrecen Medical and Health Science Center Debrecen, Hungary, 4032 Collapse << |
NCT01872598 | Alzheimer Disease | Phase 3 | Active, not recruiting | October 2019 | Spain ... more >> Hospital Universitario Ramón y Cajal Madrid, Spain, 28034 Collapse << |
NCT01694277 | Gastrointestinal Stromal Tumor... more >>s Collapse << | Phase 3 | Recruiting | December 2022 | France ... more >> Institut Bergonié Recruiting Bordeaux, France, 33000 Collapse << |
NCT00998751 | Gastro-intestinal Stromal Tumo... more >>urs Collapse << | Phase 2 | Completed | - | France ... more >> Lecesne Villejuif, France Collapse << |
NCT01410695 | Rheumatoid Arthritis (RA) | Phase 2 Phase 3 | Terminated(Sponsor decision ba... more >>sed on portfolio prioritization) Collapse << | - | Czechia ... more >> ARTMEDI UPD s.r.o Hostivice, Czechia, 25301 Collapse << |
NCT01470131 | Multiple Myeloma | Phase 3 | Terminated(Sponsor decision ba... more >>sed on portfolio prioritization) Collapse << | - | United States, Illinois ... more >> Medical and Surgical Specialists Galesburg, Illinois, United States, 61401 United States, Maryland Center for Cancer and Blood Disorders Bethesda, Maryland, United States, 20817 United States, North Carolina Carolinas Medical Center Charlotte, North Carolina, United States, 28203 Southeastern Medical Oncology Center Goldsboro, North Carolina, United States, 27534 United States, Wisconsin Froedtert & Medical College of Wisconsin-CLCC Milwaukee, Wisconsin, United States, 53226 France CHU Estaing Clermont Ferrand, France Centre Hospitalier Sud Francilien Corbeil-Essonnes, France CH Le Mans Le Mans, France Hôpital Universitaire Dupuytren Limoges, France Hôpital Ambroise Paré Marseille, France Hôpital de l'Hôtel Dieu Nantes, France Hôpital Saint Louis Paris, France Centre Hospitalier Saint Jean Perpignan, France Collapse << |
NCT03766295 | Locally Advanced or Metastatic... more >> Pancreatic Cancer Collapse << | Phase 3 | Recruiting | December 2020 | France ... more >> Centre Hospitalier de Longjumeau Recruiting Longjumeau, France, 91160 Collapse << |
NCT00976118 | Alzheimer's Disease | Phase 2 | Completed | - | - |
NCT00814073 | Indolent Systemic Mastocytosis | Phase 3 | Completed | - | United States, California ... more >> UC Davis Health System , Department of Dermatology Sacramento, California, United States, 95816 United States, Texas MD Anderson Cancer Centre Houston, Texas, United States, 77030 France CHU d'Amiens Amiens, France Hôpital Avicenne Bobigny, France CHU de Brest Brest, France CHU de Caen Caen, France CHU Clermont Ferrand Clermont Ferrand, France, 63000 Hôpital Claude Huriez Lille, France CHU Dupuytren Limoges, France Hôpital Ambroise Paré Marseille, France Hôpital Nord Marseille, France Hôpital Central Nancy, France CHU Hôtel Dieu Nantes, France Hôpital l'Archet II Nice, France Hôpital Necker Paris, France Hôpital Tenon Paris, France CHU Lyon Sud Pierre Bénite, France, 69495 Centre Hospitalier Lyon Sud Pierre-Bénite, France CHU Milétrie Poitiers, France CHU Hôpital Sud Rennes, France CHU de Saint-Etienne Saint-Etienne, France Hôpital Purpan Toulouse, France Hôpital Bretonneau Tours, France Hôpital des Hauts Clos Troyes, France Collapse << |
NCT03761225 | Metastatic Castrate Resistant ... more >>Prostate Cancer Collapse << | Phase 3 | Recruiting | September 2020 | France ... more >> Polyclinique d'oncologie de Gentilly Recruiting Nancy, France, 54100 Contact: Dominique Spaeth, MD Collapse << |
NCT02588677 | Amyotrophic Lateral Sclerosis ... more >>(ALS) Collapse << | Phase 2 Phase 3 | Completed | - | Spain ... more >> Hospital Carlos III Madrid, Spain, 28029 Collapse << |
NCT03556956 | Colorectal Cancer Metastatic | Phase 2 Phase 3 | Active, not recruiting | December 31, 2020 | Russian Federation ... more >> Omsk Clinical oncology dispensary Omsk, Russian Federation, 644013 Collapse << |
NCT00913432 | Rheumatoid Arthritis | Phase 2 | Completed | - | - |
NCT01280565 | Metastatic Melanoma | Phase 3 | Recruiting | December 2020 | France ... more >> Hôpital Sainte Marguerite Recruiting Marseille, France, 13274 Contact: Jean-Jacques GROB, MD, PhD Collapse << |
NCT03771040 | Asthma | Phase 3 | Recruiting | December 2020 | Hungary ... more >> University of Debrecen Medical and Health Science Center Recruiting Debrecen, Hungary, 4032 Collapse << |
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