CAS No.: 334951-92-7
MEK inhibitor Catalog No. CSN18222
Synonyms: NCGC-00346543
MEK inhibitor is a potent MEK inhibitor, antitumor agent.
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02263898 Recurrent Melanoma ... more >> Stage IV Melanoma Collapse << Phase 2 Withdrawn(closed without enrol... more >>lment) Collapse << - United States, California ... more >> Jonsson Comprehensive Cancer Center Los Angeles, California, United States, 90095 Collapse << NCT01271803 Malignant Melanoma Phase 1 Completed - United States, California ... more >> UCLA Department of Medicine Los Angeles, California, United States, 90024 University of California at San Francisco San Francisco, California, United States, 94115 The Angeles Clinic and Research Institute, Santa Monica Office Santa Monica, California, United States, 90025 United States, Colorado University of Colorado; Anschutz Cancer Pavilion Aurora, Colorado, United States, 80045 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637 United States, Indiana Indiana University - Department of Medicine, Division of Gastroenterology/Hepatology Indianapolis, Indiana, United States, 46202 United States, Michigan Karmanos Cancer Inst. ; Hudson Webber; Cancer Research Building Detroit, Michigan, United States, 48201 United States, New York New York University Medical Center New York, New York, United States, 10036 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Australia, Victoria Peter Maccallum Cancer Institute; Medical Oncology Melbourne, Victoria, Australia, 3000 Collapse << NCT01649336 Epithelial Ovarian Cancer ... more >> Fallopian Tube Cancer Peritoneal Cancer Collapse << Phase 1 Completed - United States, Arizona ... more >> Scottsdale, Arizona, United States United States, Indiana Lafayette, Indiana, United States United States, New York New York, New York, United States United States, Oklahoma Oklahoma City, Oklahoma, United States Collapse << - 更多
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 334951-92-7 | 储存条件 |
|
|
| 分子式 | C26H26N4O2 | 运输 | 蓝冰 | |
| 分子量 | 426.51 | 别名 | NCGC-00346543 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT02263898 | Recurrent Melanoma ... more >> Stage IV Melanoma Collapse << | Phase 2 | Withdrawn(closed without enrol... more >>lment) Collapse << | - | United States, California ... more >> Jonsson Comprehensive Cancer Center Los Angeles, California, United States, 90095 Collapse << |
| NCT01271803 | Malignant Melanoma | Phase 1 | Completed | - | United States, California ... more >> UCLA Department of Medicine Los Angeles, California, United States, 90024 University of California at San Francisco San Francisco, California, United States, 94115 The Angeles Clinic and Research Institute, Santa Monica Office Santa Monica, California, United States, 90025 United States, Colorado University of Colorado; Anschutz Cancer Pavilion Aurora, Colorado, United States, 80045 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637 United States, Indiana Indiana University - Department of Medicine, Division of Gastroenterology/Hepatology Indianapolis, Indiana, United States, 46202 United States, Michigan Karmanos Cancer Inst. ; Hudson Webber; Cancer Research Building Detroit, Michigan, United States, 48201 United States, New York New York University Medical Center New York, New York, United States, 10036 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Australia, Victoria Peter Maccallum Cancer Institute; Medical Oncology Melbourne, Victoria, Australia, 3000 Collapse << |
| NCT01649336 | Epithelial Ovarian Cancer ... more >> Fallopian Tube Cancer Peritoneal Cancer Collapse << | Phase 1 | Completed | - | United States, Arizona ... more >> Scottsdale, Arizona, United States United States, Indiana Lafayette, Indiana, United States United States, New York New York, New York, United States United States, Oklahoma Oklahoma City, Oklahoma, United States Collapse << |
| NCT01138085 | Cancer | Phase 1 | Completed | - | United States, Colorado ... more >> GSK Investigational Site Aurora, Colorado, United States, 80045 United States, Connecticut GSK Investigational Site New Haven, Connecticut, United States, 06520 United States, Massachusetts GSK Investigational Site Boston, Massachusetts, United States, 02114 GSK Investigational Site Boston, Massachusetts, United States, 02215 United States, New Jersey GSK Investigational Site New Brunswick, New Jersey, United States, 08901 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37232 United States, Texas GSK Investigational Site Dallas, Texas, United States, 75246 GSK Investigational Site Houston, Texas, United States, 77230-1439 GSK Investigational Site San Antonio, Texas, United States, 78229 United States, Utah GSK Investigational Site Salt Lake City, Utah, United States, 84112-5550 Collapse << |
| NCT01438554 | Solid Tumors ... more >>Thyroid Cancer Soft-tissue Sarcoma Cholangiocarcinoma Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT00817518 | Neoplasms | Phase 1 | Completed | - | France ... more >> Marseille, France, 13385 Paris, France, 75231 Paris, France, 75651 Villejuif, France, 94805 Germany Essen, Germany, 45122 Netherlands Amsterdam, Netherlands, 1066 CX Spain Barcelona, Spain, 08003 Madrid, Spain, 28050 Sevilla, Spain, 41013 United Kingdom Cambridge, United Kingdom, CB2 2QQ London, United Kingdom, SW3 6JJ Oxford, United Kingdom, OX3 7LJ Collapse << |
| NCT00773526 | Neoplasms | Phase 1 | Completed | - | France ... more >> Villejuif, France, 94805 Spain Barcelona, Spain, 08003 United Kingdom Sutton, United Kingdom, SM2 5PT Collapse << |
| NCT02093546 | - | - | Active, not recruiting | August 31, 2019 | United States, Texas ... more >> M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT01271803 | - | - | Completed | - | - |
| NCT02124772 | Cancer | Phase 1 | Recruiting | October 15, 2020 | United States, Arizona ... more >> Novartis Investigative Site Recruiting Phoenix, Arizona, United States, 85016-7710 United States, California Novartis Investigative Site Recruiting San Francisco, California, United States United States, Maryland Novartis Investigative Site Recruiting Baltimore, Maryland, United States, 21287 United States, Massachusetts Novartis Investigative Site Recruiting Boston, Massachusetts, United States, 02115 United States, Minnesota Novartis Investigative Site Recruiting Minneapolis, Minnesota, United States, 55455 United States, New York Novartis Investigative Site Recruiting New York, New York, United States, 10065 United States, Ohio Novartis Investigative Site Recruiting Cincinnati, Ohio, United States, 45229 United States, Pennsylvania Novartis Investigative Site Recruiting Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee Novartis Investigative Site Recruiting Memphis, Tennessee, United States, 38105-3678 United States, Washington Novartis Investigative Site Recruiting DC, Washington, United States, DC 20010 Australia, New South Wales Novartis Investigative Site Recruiting Westmead, New South Wales, Australia, 2145 Canada, Ontario Novartis Investigative Site Recruiting Toronto, Ontario, Canada, M5G 1X8 France Novartis Investigative Site Recruiting Paris Cedex 05, France, 75248 Novartis Investigative Site Recruiting Villejuif Cedex, France, 94805 United Kingdom Novartis Investigative Site Recruiting Sutton, Surrey, United Kingdom, SM2 5PT Novartis Investigative Site Recruiting London, United Kingdom, WC1N 3JH Collapse << |
| NCT01693068 | N-Ras Mutated Locally Advanced... more >> or Metastasis Malignant Cutaneous Melanoma Collapse << | Phase 2 | Completed | - | - |
| NCT01586624 | Cancer Non Sm... more >>all Cell Lung Cancer Collapse << | Phase 1 | Active, not recruiting | March 2019 | United Kingdom ... more >> Cambridge Cancer Trials Centre (S4), Box 279, Addenbrooke's Hospital Hills Road, Cambridge, United Kingdom, CB2 0QQ The Christie NHS Foundation Trust Withington, Manchester, United Kingdom, M20 4BX Churchill Hospital Headington, Oxford, United Kingdom, OX3 7LJ The Freeman Hospital Newcastle, United Kingdom, NE7 7DN Collapse << |
| NCT02427893 | Melanoma | Phase 3 | Withdrawn(no patients were enr... more >>olled) Collapse << | - | United States, Maryland ... more >> The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 Collapse << |
| NCT00948467 | Advanced Non-hematologic Malig... more >>nancies Advanced Metastatic Melanoma Collapse << | Phase 1 | Completed | - | United States, Michigan ... more >> Wayne State University Karmanos Cancer Institute Detriot, Michigan, United States, 48201 United States, New York Roswell Park Cancer Institute Buffalo, New York, United States, 14263 Collapse << |
| NCT01581060 | Advanced Solid Tumours | Phase 1 Phase 2 | Terminated(Study terminated fo... more >>r business reasons) Collapse << | - | United Kingdom ... more >> Queen's University Belfast Cancer Centre Belfast, United Kingdom, BT9 7AB Beatson West of Scotland Cancer Centre Glasgow, United Kingdom, G12 0YN St James' Institute of Oncology Leeds, United Kingdom, LS9 7TF Christie NHS Foundation Trust, Oak Road Treatment Centre Manchester, United Kingdom, M20 4BX Sir Bobby Robson Cancer Trials Research Centre Newcastle Upon Tyne, United Kingdom, NE7 7DN Collapse << |
| NCT01336634 | Cancer | Phase 2 | Active, not recruiting | December 1, 2020 | - |
| NCT01693068 | - | - | Completed | - | - |
| NCT01752569 | AIDS-related Kaposi's Sarcoma | Phase 1 Phase 2 | Active, not recruiting | June 2018 | United Kingdom ... more >> Brighton and Sussex University Hospitals Brighton, United Kingdom, BN2 5BE Beatson West of Scotland Cancer Centre Glasgow, United Kingdom, G12 0YN Chelsea & Westminster Hospital London, United Kingdom, SW10 9NH The Christie Hospital Manchester, United Kingdom, M20 4BX Sheffield Teaching Hospitals NHS Foundation Trust Sheffield, United Kingdom, S10 2SJ Collapse << |
| NCT01336634 | - | - | Active, not recruiting | - | - |
| NCT02022982 | KRAS Mutant Non-Small Cell Lun... more >>g Cancer Solid Tumors Collapse << | Phase 1 Phase 2 | Active, not recruiting | December 2020 | United States, Massachusetts ... more >> Dana Farber Cancer Institute Boston, Massachusetts, United States, 02115 Collapse << |
| NCT01371487 | Cancer | Phase 1 | Completed | - | United States, Michigan ... more >> GSK Investigational Site Detroit, Michigan, United States, 48201 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37203 United States, Texas GSK Investigational Site San Antonio, Texas, United States, 78229 Collapse << |
| NCT02407509 | Solid Tumours ... more >> Multiple Myeloma Collapse << | Phase 1 | Recruiting | June 2021 | United Kingdom ... more >> Royal Marsden NHS Foundation Trust Recruiting Sutton, Surrey, United Kingdom, SM2 5PT Contact: Udai Banerji, MBBS, PhD Guy's and St Thomas' Hospital Not yet recruiting London, United Kingdom Contact: Alison Turner, PhD alison.turner@icr.ac.uk Contact: Joanna Dawes, PhD DDU3808@icr.ac.uk Collapse << |
| NCT02685657 | Triple Negative Breast Cancer | Phase 2 | Unknown | - | - |
| NCT03736850 | Locally Advanced or Metastatic... more >> Solid Tumors Collapse << | Phase 1 | Recruiting | January 13, 2021 | China, Beijing ... more >> People's Liberation Army 307 Hospital Recruiting Beijing, Beijing, China Contact: Jianming Xu Collapse << |
| NCT03516123 | Solid Tumor, Adult | Phase 1 | Recruiting | April 2020 | Australia, New South Wales ... more >> Blacktown Cancer and Haematology Centre Recruiting Blacktown, New South Wales, Australia Orange Health Service Recruiting Orange, New South Wales, Australia, 2800 St Vincent's Hospital Sydney Recruiting Sydney, New South Wales, Australia Australia, Western Australia Linear Clinical Research Recruiting Perth, Western Australia, Australia Collapse << |
| NCT01767454 | Solid Tumours | Phase 1 | Completed | - | United States, California ... more >> GSK Investigational Site Los Angeles, California, United States, 90025 GSK Investigational Site San Francisco, California, United States, 94115 United States, Massachusetts GSK Investigational Site Boston, Massachusetts, United States, 02215 United States, Missouri GSK Investigational Site Saint Louis, Missouri, United States, 63110 United States, New York GSK Investigational Site New York, New York, United States, 10065 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37232 United States, Texas GSK Investigational Site Houston, Texas, United States, 77030 Collapse << |
| NCT02296112 | Recurrent Melanoma ... more >> Stage IIIB Melanoma Stage IIIC Melanoma Stage IV Melanoma Collapse << | Phase 2 | Recruiting | January 2024 | United States, District of Col... more >>umbia Georgetown University Medical Center Recruiting Washington, District of Columbia, United States, 20007 Contact: Bridget Haley 202-687-6871 Principal Investigator: Suthee Rapisuwon, MD United States, Massachusetts Dana-Farber Cancer Institute Recruiting Boston, Massachusetts, United States, 02115 Contact: Keith T Flaherty, MD 617-724-4000 KFLAHERTY@mgh.harvard.edu Principal Investigator: Keith T. Flaherty, MD United States, New York Memorial Sloan-Kettering Cancer Center Withdrawn New York, New York, United States, 10021 United States, Pennsylvania University of Pennsylvania Cancer Center Withdrawn Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee Vanderbilt-Ingram Cancer Center Recruiting Nashville, Tennessee, United States, 37232 Contact: B. VICC Clinical Trials Information Program 800-811-8480 Principal Investigator: Douglas B. Johnson, MD United States, Texas M D Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Anna Vardeleon 713-794-4274 asreckew@mdanderson.org Principal Investigator: Michael A. Davies, MD Collapse << |
| NCT00085787 | Advanced Cancer | Phase 1 | Completed | - | United States, Colorado ... more >> University of Colorado Cancer Center, Anschutz Cancer Center Aurora, Colorado, United States, 80010 United States, Minnesota Mayo Clinic Rochester Rochester, Minnesota, United States, 55905 United States, Pennsylvania Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111 Collapse << |
| NCT02151084 | Biliary Tract Carcinoma ... more >> Gallbladder Carcinoma Collapse << | Phase 2 | Completed | - | Canada, Ontario ... more >> Princess Margaret Cancer Centre Toronto, Ontario, Canada, M5G 2M9 Collapse << |
| NCT03705507 | Acute Lymphoblastic Leukemia ... more >> Acute Lymphoblastic Leukemia, Adult Acute Lymphoblastic Leukemia, Pediatric Acute Lymphoblastic Leukemia, in Relapse Acute Lymphoblastic Leukemia Recurrent Collapse << | Phase 1 Phase 2 | Recruiting | March 17, 2021 | United Kingdom ... more >> Birmingham Children's Hospital Recruiting Birmingham, United Kingdom Principal Investigator: Alice Norton Alder Hey Children's Hospital Recruiting Liverpool, United Kingdom Principal Investigator: Mark Caswell Department of Paediatric Oncology, Royal Marsden Hospital, Sutton Recruiting London Borough of Sutton, United Kingdom Principal Investigator: Donna Lancaster Haemato-Oncology Adult Unit, Royal Marsden Hospital, Sutton Recruiting London Borough of Sutton, United Kingdom Sub-Investigator: David Taussig University College Hospital Recruiting London, United Kingdom Principal Investigator: Adele Fielding The Christie Hospital Recruiting Manchester, United Kingdom Principal Investigator: Anna Castleton Freeman Hospital Recruiting Newcastle, United Kingdom Sub-Investigator: Tobias Menne Great North Children's Hospital, Royal Victoria Infirmary Recruiting Newcastle, United Kingdom Principal Investigator: Geoff Shenton Collapse << |
| NCT01166126 | - | - | Terminated | - | - |
| NCT00959127 | Advanced Solid Tumors ... more >> Advanced or Metastatic Biliary Cancer Metastatic Colorectal Cancer Collapse << | Phase 1 | Completed | - | United States, California ... more >> University of California, Los Angeles Los Angeles, California, United States, 90095 United States, Colorado University of Colorado Cancer Center Aurora, Colorado, United States, 80045 United States, Maryland The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231-1000 United States, Massachusetts Dana-Farber/Harvard Cancer Center Boston, Massachusetts, United States, 02114 United States, Michigan University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48109 United States, Missouri Washington University School of Medicine St. Louis, Missouri, United States, 63110 United States, Ohio Ohio State University Columbus, Ohio, United States, 43221 United States, Tennessee Sarah Cannon Research Institute Nashville, Tennessee, United States, 37203 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 South Texas Accelerated Research Therapeutics San Antonio, Texas, United States, 78229 Collapse << |
| NCT01333475 | Colorectal Neoplasms | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT01217450 | Recurrent Colon Cancer ... more >> Recurrent Rectal Cancer Stage IVA Colon Cancer Stage IVA Rectal Cancer Stage IVB Colon Cancer Stage IVB Rectal Cancer Unspecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> National Cancer Institute Medicine Branch Bethesda, Maryland, United States, 20892 United States, Wisconsin University of Wisconsin Hospital and Clinics Madison, Wisconsin, United States, 53792 Wisconsin Clinical Cancer Center Milwaukee, Wisconsin, United States, 53226 Collapse << |
| NCT01166126 | Mucosal Melanoma ... more >> Recurrent Melanoma Stage IV Melanoma Collapse << | Phase 2 | Terminated | - | United States, Florida ... more >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 Collapse << |
| NCT02105350 | Biliary Tract Carcinoma ... more >> Gallbladder Carcinoma Collapse << | Phase 1 | Withdrawn(Study was never init... more >>iated) Collapse << | - | - |
| NCT03004105 | Malignant Neoplasm of Respirat... more >>ory and Intrathoracic Organ Carcinoma Advanced Lung Cancer Recurrent Nonsmall Cell Lung Cancer Collapse << | Phase 2 | Withdrawn(Inadequate funding) | May 2024 | - |
| NCT01333475 | - | - | Completed | - | - |
| NCT01392521 | Neoplasms | Phase 1 | Completed | - | United States, Arizona ... more >> Scottsdale, Arizona, United States, 85260 United States, Nevada Las Vegas, Nevada, United States, 89169 United States, South Carolina Greenville, South Carolina, United States, 29605 United States, Texas Houston, Texas, United States, 77030 Tyler, Texas, United States, 75702 United States, Washington Vancouver, Washington, United States, 98684 Germany Freiburg, Baden-Württemberg, Germany, 79106 Netherlands Rotterdam, Netherlands, 3015 CE Collapse << |
| NCT01668017 | - | - | Terminated(The sponsor decided... more >> not to conduct the expansion part of trial (part 2)) Collapse << | - | - |
| NCT01668017 | Advanced Solid Tumors ... more >> Hepatocellular Carcinoma Collapse << | Phase 1 | Terminated(The sponsor decided... more >> not to conduct the expansion part of trial (part 2)) Collapse << | - | Japan ... more >> Please contact Merck Serono Co., Ltd for recruiting locations in, Japan Collapse << |
| NCT01584648 | Melanoma | Phase 3 | Active, not recruiting | October 15, 2018 | - |
| NCT01740648 | Recurrent Rectal Cancer ... more >> Stage IIA Rectal Cancer Stage IIB Rectal Cancer Stage IIC Rectal Cancer Stage IIIA Rectal Cancer Stage IIIB Rectal Cancer Stage IIIC Rectal Cancer Collapse << | Phase 1 | Active, not recruiting | December 31, 2022 | United States, Missouri ... more >> Washington University Saint Louis, Missouri, United States, 63110 United States, Ohio Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center Columbus, Ohio, United States, 43210 United States, Tennessee Vanderbilt University Nashville, Tennessee, United States Collapse << |
| NCT01941927 | Melanoma | Phase 2 | Unknown | May 2016 | United States, California ... more >> UCSF Helen Diller Family Comprehensive Cancer Center San Francisco, California, United States, 94115 United States, New York Memorial Sloan-Kettering Cancer Center New York City, New York, United States, 10065 Collapse << |
| NCT01072175 | Cancer | Phase 2 | Completed | - | United States, California ... more >> Novartis Investigative Site Los Angeles, California, United States, 90025 Novartis Investigative Site San Francisco, California, United States, 94115 United States, Colorado Novartis Investigative Site Aurora, Colorado, United States, 80045 United States, Connecticut Novartis Investigative Site New Haven, Connecticut, United States, 06520 United States, Florida Novartis Investigative Site Tampa, Florida, United States, 33612 United States, Maryland Novartis Investigative Site Lutherville-Timonium, Maryland, United States, 21093 United States, Massachusetts Novartis Investigative Site Boston, Massachusetts, United States, 02114 Novartis Investigative Site Boston, Massachusetts, United States, 02215 United States, Minnesota Novartis Investigative Site Rochester, Minnesota, United States, 55905 United States, Pennsylvania Novartis Investigative Site Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee Novartis Investigative Site Nashville, Tennessee, United States, 37203 Novartis Investigative Site Nashville, Tennessee, United States, 37232 United States, Texas Novartis Investigative Site Houston, Texas, United States, 77030-4009 Australia, New South Wales Novartis Investigative Site Westmead, New South Wales, Australia, 2145 Australia, Victoria Novartis Investigative Site Heidelberg, Victoria, Australia, 3084 Collapse << |
| NCT00687622 | Solid Tumours | Phase 1 | Completed | - | United States, Arizona ... more >> GSK Investigational Site Scottsdale, Arizona, United States, 85258 United States, Colorado GSK Investigational Site Aurora, Colorado, United States, 80045 United States, Florida GSK Investigational Site Fort Myers, Florida, United States, 33905 GSK Investigational Site Ocoee, Florida, United States, 34761 United States, Nevada GSK Investigational Site Las Vegas, Nevada, United States, 89169 United States, New York GSK Investigational Site Albany, New York, United States, 12206 United States, Ohio GSK Investigational Site Kettering, Ohio, United States, 45409 United States, Pennsylvania GSK Investigational Site Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37203 United States, Texas GSK Investigational Site Dallas, Texas, United States, 75246 GSK Investigational Site Houston, Texas, United States, 77030 United States, Virginia GSK Investigational Site Norfolk, Virginia, United States, 23502 Collapse << |
| NCT02042443 | - | - | Completed | - | - |
| NCT02042443 | Adult Cholangiocarcinoma ... more >> Advanced Adult Hepatocellular Carcinoma BCLC Stage C Adult Hepatocellular Carcinoma BCLC Stage D Adult Hepatocellular Carcinoma Hilar Cholangiocarcinoma Localized Non-Resectable Adult Liver Carcinoma Recurrent Adult Liver Carcinoma Recurrent Childhood Liver Cancer Recurrent Extrahepatic Bile Duct Carcinoma Recurrent Gallbladder Carcinoma Stage II Gallbladder Cancer Stage III Childhood Hepatocellular Carcinoma Stage IIIA Gallbladder Cancer Stage IIIB Gallbladder Cancer Stage IV Childhood Hepatocellular Carcinoma Stage IV Distal Bile Duct Cancer Stage IVA Gallbladder Cancer Stage IVB Gallbladder Cancer Unresectable Extrahepatic Bile Duct Carcinoma Collapse << | Phase 2 | Completed | - | - |
| NCT01613261 | Advanced Nonhematologic Malign... more >>ancies Collapse << | Phase 1 | Withdrawn | November 2015 | United States, Texas ... more >> South Texas Accelerated Research Therapeutics (START) San Antonio, Texas, United States, 78229 Collapse << |
| NCT00957580 | - | - | Terminated(The trial has been ... more >>terminated due to an estimated low probability of clinical benefit based on limited anti-leukemic effects observed in safety run-in (Part 1)) Collapse << | - | - |
| NCT00957580 | Leukemia, Myeloid, Acute ... more >> Hematologic Neoplasms Collapse << | Phase 2 | Terminated(The trial has been ... more >>terminated due to an estimated low probability of clinical benefit based on limited anti-leukemic effects observed in safety run-in (Part 1)) Collapse << | - | United States, Illinois ... more >> Northwestern University Chicago, Illinois, United States United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States United States, Massachusetts Beth Israel Deaconess Medical Center Boston, Massachusetts, United States Dana Farber Cancer Institute Boston, Massachusetts, United States United States, Texas University of Texas - MD Anderson Cancer Center Houston, Texas, United States France Hospital Hotel Dieu, Service D'Hematologie Nantes, Cedex, France Hospital Edouard Herriot, Service d'Hematologie Clinique Lyon Cedex, France Hospital Saint Louis, Service des Maladies du Sang Paris, France CHU du Haut-Leveque, Service des Maladies du Sang Unite de Recherche Clinique Pessac, France Collapse << |
| NCT01072175 | - | - | Completed | - | - |
| NCT01192165 | Cancer | Phase 1 | Completed | - | United States, Arizona ... more >> GSK Investigational Site Scottsdale, Arizona, United States, 85259 United States, California GSK Investigational Site Duarte, California, United States, 91010 GSK Investigational Site Sacramento, California, United States, 95817 United States, Colorado GSK Investigational Site Denver, Colorado, United States, 80218 United States, Nevada GSK Investigational Site Las Vegas, Nevada, United States, 89169 United States, New York GSK Investigational Site Albany, New York, United States, 12206 United States, South Carolina GSK Investigational Site Greenville, South Carolina, United States, 29605 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37203 United States, Texas GSK Investigational Site Dallas, Texas, United States, 75246 GSK Investigational Site Houston, Texas, United States, 77030 GSK Investigational Site Tyler, Texas, United States, 75702 United States, Virginia GSK Investigational Site Norfolk, Virginia, United States, 23502 United States, Washington GSK Investigational Site Vancouver, Washington, United States, 98684 Canada, Ontario GSK Investigational Site Toronto, Ontario, Canada, M5G 2M9 France GSK Investigational Site Caen Cedex 9, France, 14033 GSK Investigational Site Marseille cedex 5, France, 13385 GSK Investigational Site Saint-Herblain cedex, France, 44805 GSK Investigational Site Toulouse cedex, France, 31052 Korea, Republic of GSK Investigational Site Seoul, Korea, Republic of, 120-752 GSK Investigational Site Seoul, Korea, Republic of, 135-710 Collapse << |
| NCT01204177 | Carcinoma, Hepatocellular | Phase 2 | Completed | - | Hong Kong ... more >> Shatin, New Territories, Hong Kong Hong Kong, Hong Kong Korea, Republic of Jung-gu, Daegu Gwang''yeogsi, Korea, Republic of, 700-721 Goyang-si, Gyeonggido, Korea, Republic of, 410-769 Busan, Korea, Republic of, 602-739 Seoul, Korea, Republic of, 110-744 Seoul, Korea, Republic of, 120-752 Seoul, Korea, Republic of, 135-710 Seoul, Korea, Republic of, 138-736 Singapore Singapore, Singapore, 228510 Singapore, Singapore, 258499 Taiwan Kaohsiung, Taiwan, 833 Tainan, Taiwan, 736 Tainan, Taiwan Taipei, Taiwan, 100 Collapse << |
| NCT00147550 | Melanoma Colo... more >>nic Neoplasms Breast Neoplasms Collapse << | Phase 1 Phase 2 | Terminated(See termination rea... more >>son in detailed description.) Collapse << | - | United States, Alabama ... more >> Pfizer Investigational Site Birmingham, Alabama, United States, 35233-2115 Pfizer Investigational Site Birmingham, Alabama, United States, 35233 Pfizer Investigational Site Birmingham, Alabama, United States, 35294 United States, California Pfizer Investigational Site La Jolla, California, United States, 92037 Pfizer Investigational Site La Jolla, California, United States, 92093 Pfizer Investigational Site La Mesa, California, United States, 91942 Pfizer Investigational Site Los Angeles, California, United States, 90025 Pfizer Investigational Site San Diego, California, United States, 92103 Pfizer Investigational Site San Diego, California, United States, 92123 Pfizer Investigational Site Santa Monica, California, United States, 90404 United States, Florida Pfizer Investigational Site Tampa, Florida, United States, 33612 United States, Michigan Pfizer Investigational Site Detroit, Michigan, United States, 48201 Pfizer Investigational Site Detroit, Michigan, United States, 48202 United States, Minnesota Pfizer Investigational Site Rochester, Minnesota, United States, 55905 United States, New York Pfizer Investigational Site New York, New York, United States, 10021 Pfizer Investigational Site New York, New York, United States, 10022 United States, Ohio Pfizer Investigational Site Cleveland, Ohio, United States, 44106 Collapse << |
| NCT01584648 | - | - | Active, not recruiting | - | - |
| NCT02079740 | Advanced Malignant Solid Neopl... more >>asm KRAS Gene Mutation Metastatic Malignant Solid Neoplasm NRAS Gene Mutation Recurrent Colorectal Carcinoma Recurrent Lung Carcinoma Recurrent Malignant Solid Neoplasm Recurrent Pancreatic Carcinoma Stage III Colorectal Cancer AJCC v7 Stage III Lung Cancer AJCC v7 Stage III Pancreatic Cancer AJCC v6 and v7 Stage IIIA Colorectal Cancer AJCC v7 Stage IIIB Colorectal Cancer AJCC v7 Stage IIIC Colorectal Cancer AJCC v7 Stage IV Colorectal Cancer AJCC v7 Stage IV Lung Cancer AJCC v7 Stage IV Pancreatic Cancer AJCC v6 and v7 Stage IVA Colorectal Cancer AJCC v7 Stage IVB Colorectal Cancer AJCC v7 Unresectable Malignant Neoplasm Collapse << | Phase 1 Phase 2 | Recruiting | - | United States, Massachusetts ... more >> Massachusetts General Hospital Cancer Center Suspended Boston, Massachusetts, United States, 02114 Dana-Farber Cancer Institute Recruiting Boston, Massachusetts, United States, 02215 Contact: Ryan B. Corcoran 877-726-5130 Principal Investigator: Ryan B. Corcoran Collapse << |
| NCT03088176 | Melanoma BRAF... more >> Gene Mutation Collapse << | Phase 1 | Recruiting | June 30, 2021 | United States, Tennessee ... more >> West Cancer Center Recruiting Germantown, Tennessee, United States, 38138 Contact: Ari VanderWalde, MD, MPH 901-683-0055 ext 63015 avanderw@westclinic.com Contact: Nibedita Chakraborty 901-683-0055 ext 63023 nchakraborty@westclinic.com Collapse << |
| NCT01935973 | Endometrial Adenocarcinoma ... more >> Endometrial Clear Cell Adenocarcinoma Endometrial Mixed Adenocarcinoma Endometrial Serous Adenocarcinoma Endometrial Undifferentiated Carcinoma Recurrent Uterine Corpus Carcinoma Collapse << | Phase 1 | Active, not recruiting | - | - |
| NCT01037127 | Cancer | Phase 2 | Completed | - | United States, California ... more >> GSK Investigational Site Los Angeles, California, United States, 90024 United States, Colorado GSK Investigational Site Aurora, Colorado, United States, 80045 United States, New York GSK Investigational Site New York, New York, United States, 10016 United States, Pennsylvania GSK Investigational Site Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37203 GSK Investigational Site Nashville, Tennessee, United States, 37232-6307 United States, Texas GSK Investigational Site Houston, Texas, United States, 77030-4009 Australia, New South Wales GSK Investigational Site Westmead, New South Wales, Australia, 2145 Australia, Victoria GSK Investigational Site East Melbourne, Victoria, Australia, 3002 Australia, Western Australia GSK Investigational Site Nedlands, Western Australia, Australia, 6009 Collapse << |
| NCT01849874 | Low-grade Serous Ovarian Cance... more >>r Low-grade Serous Fallopian Tube Cancer Low-grade Serous Peritoneal Cancer Collapse << | Phase 3 | Active, not recruiting | September 2019 | - |
| NCT01037127 | - | - | Completed | - | - |
| NCT03581487 | Recurrent Non-Small Cell Lung ... more >>Carcinoma Stage IV Lung Cancer Stage IVA Lung Cancer Stage IVB Lung Cancer Collapse << | Phase 1 Phase 2 | Not yet recruiting | April 16, 2020 | United States, Texas ... more >> M D Anderson Cancer Center Not yet recruiting Houston, Texas, United States, 77030 Contact dlgibbon@mdanderson.org Collapse << |
| NCT03754179 | Melanoma | Phase 1 Phase 2 | Recruiting | December 1, 2020 | Belgium ... more >> UZ Brussel Recruiting Jette, Brabant, Belgium, 1090 Contact: Bart Neyns, Phd,Md 0032(0)2477 64 15 bart.neyns@uzbrussel.be Principal Investigator: Bart Neyns, Phd,Md Collapse << |
| NCT01750918 | Cancer | Phase 2 | Active, not recruiting | April 30, 2019 | United States, Arizona ... more >> Novartis Investigative Site Scottsdale, Arizona, United States, 85259 United States, California Novartis Investigative Site San Francisco, California, United States, 94115 United States, Massachusetts Novartis Investigative Site Boston, Massachusetts, United States, 02114 Novartis Investigative Site Boston, Massachusetts, United States, 02215 United States, New York Novartis Investigative Site New York, New York, United States, 10065 United States, North Carolina Novartis Investigative Site Chapel Hill, North Carolina, United States, 27599 United States, Pennsylvania Novartis Investigative Site Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee Novartis Investigative Site Nashville, Tennessee, United States, 37203 Belgium Novartis Investigative Site Bruxelles, Belgium, 1200 Novartis Investigative Site Leuven, Belgium, 3000 France Novartis Investigative Site Paris cedex 12, France, 75571 Novartis Investigative Site Villejuif Cedex, France, 94805 Italy Novartis Investigative Site Milano, Lombardia, Italy, 20162 Novartis Investigative Site Candiolo (TO), Piemonte, Italy, 10060 Japan Novartis Investigative Site Aichi, Japan, 464-8681 Novartis Investigative Site Chiba, Japan, 277-8577 Netherlands Novartis Investigative Site Amsterdam, Netherlands, 1066 CX Novartis Investigative Site Utrecht, Netherlands, 3584 CX Spain Novartis Investigative Site Barcelona, Spain, 08035 United Kingdom Novartis Investigative Site Birmingham, United Kingdom, B15 2TH Collapse << |
| NCT01085331 | Metastatic Colorectal Cancer | Phase 1 Phase 2 | Terminated(Conduct the randomi... more >>zed Phase 2 part not recommended due to the achieved MTD for pimasertib (45mg/day) in combination with FOLFIRI) Collapse << | - | Belgium ... more >> Research Site Leuven, Belgium Italy Research Site Napoli, Italy Spain Research Site Barcelona, Spain Collapse << |
| NCT01085331 | - | - | Terminated(Conduct the randomi... more >>zed Phase 2 part not recommended due to the achieved MTD for pimasertib (45mg/day) in combination with FOLFIRI) Collapse << | - | - |
| NCT01453387 | Advanced Solid Tumor | Phase 1 | Terminated(Due to an administr... more >>ative reason) Collapse << | - | United States, Massachusetts ... more >> Beth Israel Deaconess Medical Center Boston, Massachusetts, United States Dana-Farber Cancer Institute Boston, Massachusetts, United States United States, Michigan Karmanos Cancer Institute Detroit, Michigan, United States Collapse << |
| NCT01859351 | Advanced Solid Tumours | Phase 1 | Terminated(Study terminated fo... more >>r business reasons) Collapse << | - | United Kingdom ... more >> Royal Marsden NHS Foundation Trust Sutton, Surrey, United Kingdom, SM2 5PT Beatson West of Scotland Cancer Centre Glasgow, United Kingdom, G12 0YN Guy's and St Thomas' Foundation Trust, Guy's Hospital London, United Kingdom, SE1 9RT Collapse << |
| NCT03190915 | Activating RAS Mutation ... more >> Blasts Under 20 Percent of Bone Marrow Nucleated Cells Blasts Under 20 Percent of Peripheral Blood White Cells Juvenile Myelomonocytic Leukemia Monosomy 7 Neurofibromatosis Type 1 NF1 Gene Mutation PTPN11 Gene Mutation Splenomegaly Collapse << | Phase 2 | Recruiting | December 30, 2020 | - |
| NCT01453387 | - | - | Terminated(Due to an administr... more >>ative reason) Collapse << | - | - |
| NCT01231581 | Cancer | Phase 2 | Completed | - | Korea, Republic of ... more >> GSK Investigational Site Seoul, Korea, Republic of, 110-744 GSK Investigational Site Seoul, Korea, Republic of, 120-752 GSK Investigational Site Seoul, Korea, Republic of, 135-710 GSK Investigational Site Seoul, Korea, Republic of, 138-736 Taiwan GSK Investigational Site Gueishan Township,Taoyuan County, Taiwan, 333 GSK Investigational Site Tainan, Taiwan, 704 GSK Investigational Site Taipei, Taiwan, 112 Collapse << |
| NCT03224767 | BRAF V600E Mutation Present ... more >> Papillary Craniopharyngioma Collapse << | Phase 2 | Recruiting | August 2026 | - |
| NCT00610194 | Advanced Cancer | Phase 1 | Completed | - | United States, Arizona ... more >> Scottsdale, Arizona, United States, 85258 United States, Colorado Aurora, Colorado, United States, 80045 United States, New York Buffalo, New York, United States, 14263 Collapse << |
| NCT01390818 | Locally Advanced Solid Tumor ... more >> Metastatic Solid Tumor Breast Cancer Non Small Cell Lung Cancer Melanoma Colorectal Cancer Collapse << | Phase 1 | Completed | - | United States, Arizona ... more >> Pinnacle Oncology Hematology Scottsdale, Arizona, United States, 85258 United States, California Cedars Sinai Medical Center Los Angeles, California, United States, 90048 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States United States, New York Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 United States, Tennessee Sarah Cannon Research Institute Nashville, Tennessee, United States, 37205 United States, Texas Cancer Therapy and Research Center San Antonio, Texas, United States, 78229 Italy Merck Serono Research Site Milan, Italy Spain Merck Serono Research Site Madrid, Spain Collapse << |
| NCT01364051 | Solid Neoplasm ... more >> Stage IV Cutaneous Melanoma AJCC v6 and v7 Collapse << | Phase 1 | Active, not recruiting | - | United States, Florida ... more >> Mayo Clinic in Florida Jacksonville, Florida, United States, 32224-9980 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 Collapse << |
| NCT01231581 | - | - | Completed | - | - |
| NCT01245062 | Melanoma | Phase 3 | Completed | - | - |
| NCT02968485 | Solid Tumor | Phase 1 | Recruiting | July 2019 | China, Guangdong ... more >> The Cancer Center,Sun Yat-sen University Recruiting Guangzhou, Guangdong, China, 510060 Contact: RuiHua Xu, MD, PhD 86-20-87343008 xurh@sysucc.org.cn Collapse << |
| NCT01245062 | - | - | Completed | - | - |
| NCT01229150 | Non Small Cell Lung Carcinoma | Phase 2 | Completed | - | United States, California ... more >> University of California, Davis Davis, California, United States, 95616 University of Southern California Health Sciences Campus Los Angeles, California, United States, 90033 City of Hope Medical Group South Pasadena, California, United States, 91030 United States, Illinois University of Chicago Medical Center Chicago, Illinois, United States, 60637 United States, Maryland National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT01387204 | Cancer | Phase 1 | Completed | - | United States, Washington ... more >> GSK Investigational Site Tacoma, Washington, United States, 98418 Collapse << |
| NCT01229150 | - | - | Completed | - | - |
| NCT01597908 | Melanoma | Phase 3 | Active, not recruiting | March 18, 2019 | - |
| NCT01278615 | Recurrent Adult Diffuse Large ... more >>Cell Lymphoma Collapse << | Phase 2 | Terminated(Closed Prematurely.... more >>) Collapse << | - | United States, Illinois ... more >> Northwestern University Chicago, Illinois, United States, 60611 University of Chicago Comprehensive Cancer Center Chicago, Illinois, United States, 60637 Decatur Memorial Hospital Decatur, Illinois, United States, 62526 NorthShore University HealthSystem-Evanston Hospital Evanston, Illinois, United States, 60201 Ingalls Memorial Hospital Harvey, Illinois, United States, 60426 Illinois CancerCare-Peoria Peoria, Illinois, United States, 61615 Southern Illinois University Springfield, Illinois, United States, 62702 United States, Indiana Fort Wayne Medical Oncology and Hematology Inc-Parkview Fort Wayne, Indiana, United States, 46845 Indiana University/Melvin and Bren Simon Cancer Center Indianapolis, Indiana, United States, 46202 United States, Maryland University of Maryland/Greenebaum Cancer Center Baltimore, Maryland, United States, 21201 United States, Massachusetts Tufts Medical Center Boston, Massachusetts, United States, 02111 University of Massachusetts Memorial Health Care Worcester, Massachusetts, United States, 01605 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48109 United States, Missouri Saint John's Mercy Medical Center Saint Louis, Missouri, United States, 63141 United States, New York Weill Medical College of Cornell University New York, New York, United States, 10065 United States, Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT01278615 | - | - | Terminated(Closed Prematurely.... more >>) Collapse << | - | - |
| NCT02768766 | Uveal Melanoma | Phase 1 | Recruiting | January 2019 | United States, New York ... more >> Columbia University Medical Center Recruiting New York, New York, United States, 10032 Contact: Richard Carvajal, MD rdc2150@cumc.columbia.edu Principal Investigator: Richard Carvajal, MD Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Alexander N Shoushtari, M.D 646-888-4161 shoushta@mskcc.org United States, Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Sapna Patel, M.D 713-792-4955 sppatel@mdanderson.org Collapse << |
| NCT01597908 | - | - | Active, not recruiting | - | - |
| NCT01347866 | Advanced Cancer | Phase 1 | Terminated(Refer to Detailed D... more >>escription for documentaion of Termination Statement.) Collapse << | - | United States, California ... more >> Ronald Reagan UCLA Medical Center Los Angeles, California, United States, 90095-6984 Ronald Reagan UCLA Medical Center Los Angeles, California, United States, 90095 UCLA Medical Center Los Angeles, California, United States, 90095 UCLA Oncology Center Los Angeles, California, United States, 90095 Santa Monica - UCLA Medical Center and Orthopaedic Hospital Santa Monica, California, United States, 90404 UCLA Santa Monica Hematology Oncology Santa Monica, California, United States, 90404 United States, Colorado Anschutz Cancer Pavilion Aurora, Colorado, United States, 80045 University of Colorado Denver (CTRC) Aurora, Colorado, United States, 80045 University of Colorado Hospital Anschutz Inpatient Pavilion Aurora, Colorado, United States, 80045 University of Colorado Hospital Aurora, Colorado, United States, 80045 United States, South Carolina Medical University of South Carolina, Hollings Cancer Center Charleston, South Carolina, United States, 29425 Medical University of South Carolina Charleston, South Carolina, United States, 29425 MUSC, Investigational Drug Services Charleston, South Carolina, United States, 29425 MUSC Health East Cooper Mount Pleasant, South Carolina, United States, 29464 MUSC Specialty Care-North North Charleston, South Carolina, United States, 29406 Canada, Ontario Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 Italy Ospedale San Raffaele Milano, Italy, 20132 Spain Hospital General Vall d'Hebron Barcelona, Spain, 08035 Collapse << |
| NCT02065063 | Cancer | Phase 1 | Completed | - | United States, Massachusetts ... more >> GSK Investigational Site Boston, Massachusetts, United States, 02114 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37232 United States, Texas GSK Investigational Site Houston, Texas, United States, 77030-4009 Collapse << |
| NCT01390818 | - | - | Completed | - | - |
| NCT01428427 | Leukaemia, Myelocytic, Acute | Phase 1 | Completed | - | United States, Tennessee ... more >> GSK Investigational Site Nashville, Tennessee, United States, 37203 United States, Texas GSK Investigational Site San Antonio, Texas, United States, 78229 Collapse << |
| NCT00982865 | Solid Tumors ... more >>Cancer Collapse << | Phase 1 | Completed | - | Australia ... more >> Westmead Hospital Westmead, Australia Belgium Jules Bordet Institute Brussels, Belgium, B-1000 Ghent University Hospital Ghent, Belgium France Institute Bergonié Bordeaux, France Hôpital Beaujon Paris, France, 92118 Hopital Saint Louis Paris, France Centre Eugène Marquis Rennes, France Institute Claudius Regaud Toulouse, France, 03 31052 Netherlands Netherlands Cancer Institute - Antonie van Leeuwenhoek Hospital Amsterdam, Netherlands Collapse << |
| NCT00970359 | - | - | Completed | - | - |
| NCT00970359 | Thyroid Cancer | Not Applicable | Completed | - | United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 Collapse << |
| NCT00982865 | - | - | Completed | - | - |
| NCT02314143 | Melanoma | Phase 2 | Completed | - | France ... more >> GSK Investigational Site Bordeaux, France, 33075 GSK Investigational Site Marseille cedex 5, France, 13385 GSK Investigational Site Reims Cedex, France, 51092 GSK Investigational Site Rennes Cedex, France, 35042 GSK Investigational Site Villejuif cedex, France, 94805 Spain GSK Investigational Site Barcelona, Spain, 08036 GSK Investigational Site Madrid, Spain, 28041 Collapse << |
| NCT02185690 | Lungcancer | Phase 1 | Recruiting | April 2019 | Canada, Alberta ... more >> Cross Cancer Institute Recruiting Edmonton, Alberta, Canada, T6G1Z2 Contact: Quincy Chu, MD 780-432-8248 quincy.chu@albertahealthservices.ca Sub-Investigator: Quincy Chu, MD Canada, Ontario Juravinski Cancer Centre Recruiting Hamilton, Ontario, Canada, L8V 5C2 Contact: Peter Ellis, MD 905-387-9711 ext 64609 Peter.Ellis@jcc.hhsc.ca Sub-Investigator: Peter Ellis, MD The Ottawa Hospital Regional Cancer Centre Recruiting Ottawa, Ontario, Canada, K1G 3Y9 Contact: Scott Laurie, MD 613-737-7700 ext 70175 slaurie@ottawahospital.on.ca Sub-Investigator: Scott Laurie, MD Princess Margaret Cancer Centre Recruiting Toronto, Ontario, Canada, M5G2M9 Contact: Natasha Leighl, MD 416-946-4645 Natasha.Leighl@uhn.ca Contact: Maggie Sawczak, CRA 416-946-4501 ext 5444 Maggie.Sawczak@uhn.ca Principal Investigator: Natasha Leighl, MD Collapse << |
| NCT01347866 | - | - | Terminated(Refer to Detailed D... more >>escription for documentaion of Termination Statement.) Collapse << | - | - |
| NCT00174369 | Carcinoma, Non-Small-Cell Lung | Phase 2 | Terminated(Terminated [See Det... more >>ailed Description for Termination Reason.]) Collapse << | - | United States, California ... more >> Pfizer Investigational Site Greenbrae, California, United States, 94904 Pfizer Investigational Site La Jolla, California, United States, 92093 Pfizer Investigational Site LaJolla, California, United States, 92037 Pfizer Investigational Site San Diego, California, United States, 92103 Pfizer Investigational Site San Mateo, California, United States, 94402 United States, Florida Pfizer Investigational Site Tampa, Florida, United States, 33612 United States, Michigan Pfizer Investigational Site Ann Arbor, Michigan, United States, 48106-0995 Pfizer Investigational Site Detroit, Michigan, United States, 48201 Pfizer Investigational Site Farmington Hills, Michigan, United States, 48334 United States, Minnesota Pfizer Investigational Site Coon Rapids, Minnesota, United States, 55433 Pfizer Investigational Site Fridley, Minnesota, United States, 55432 Pfizer Investigational Site Robbinsdale, Minnesota, United States, 55422 United States, New York Pfizer Investigational Site New York, New York, United States, 11725 United States, Pennsylvania Pfizer Investigational Site Philadelphia, Pennsylvania, United States, 19111 Collapse << |
| NCT03170206 | Lung Cancer | Phase 1 Phase 2 | Recruiting | March 31, 2024 | United States, Massachusetts ... more >> Dana Farber Cancer Institute Recruiting Boston, Massachusetts, United States, 02215 Contact: Geoffrey Shapiro, MD, PhD 617-632-4942 Principal Investigator: Geoffrey Shapiro, MD Massachusetts General Hospital Not yet recruiting Boston, Massachusetts, United States, 02215 Contact: Rebecca Heist, MD 617-726-1838 Principal Investigator: Rebecca Heist, MD Collapse << |
| NCT01016483 | Pancreatic Adenocarcinoma | Phase 1 Phase 2 | Completed | - | United States, Massachusetts ... more >> For Recruiting Locations in the United States, please Contact U.S. Medical Information Rockland, Massachusetts, United States Germany For Recruiting Locations outside the United States, Please contact the Merck KGaA Communication Center Darmstadt, Germany Collapse << |
| NCT02089230 | Leukemia | Phase 1 Phase 2 | Active, not recruiting | August 2019 | United States, Texas ... more >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT03580382 | Melanoma | Phase 1 Phase 2 | Recruiting | April 2022 | United States, New York ... more >> New York University School of Medicine Recruiting New York, New York, United States, 10016 Contact: Jennifer Tiao 929-455-2437 Jennifer.Tiao@nyumc.org Principal Investigator: Jeffrey Weber, MD Collapse << |
| NCT03326310 | Chronic Myeloid Leukemia ... more >> Myelofibroses Collapse << | Phase 1 | Recruiting | September 4, 2023 | United States, Illinois ... more >> The University of Chicago Recruiting Chicago, Illinois, United States, 60637 Contact: Melissa Fridstein 773-702-9885 mfridstein@medicine.bsd.uchicago.edu Collapse << |
| NCT01725100 | Cancer | Phase 1 | Completed | - | United States, Arizona ... more >> GSK Investigational Site Goodyear, Arizona, United States, 85338 GSK Investigational Site Scottsdale, Arizona, United States, 85259 United States, Florida GSK Investigational Site Sarasota, Florida, United States, 34232 United States, Tennessee GSK Investigational Site Nashville, Tennessee, United States, 37203 Collapse << |
| NCT03696069 | - | - | Active, not recruiting | March 15, 2019 | United States, Massachusetts ... more >> Local Institution Boston, Massachusetts, United States, 02199 Collapse << |
| NCT01016483 | - | - | Completed | - | - |
| NCT03433183 | Malignant Peripheral Nerve She... more >>ath Tumors Neurofibromatosis 1 Collapse << | Phase 2 | Not yet recruiting | September 2021 | - |
| NCT01328106 | GNA11 Mutation-positive Metast... more >>atic Melanoma GNAQ Mutation-positive Metastatic Melanoma Cancer Metastatic Uveal Melanoma Collapse << | Phase 2 | Withdrawn(The study was cancel... more >>led by the sponsor prior to initiation of study enrollment. No subjects were accrued.) Collapse << | May 2012 | - |
| NCT00955773 | Cancer | Phase 1 | Completed | - | United States, Tennessee ... more >> GSK Investigational Site Nashville, Tennessee, United States, 37203 United States, Texas GSK Investigational Site San Antonio, Texas, United States, 78229 France GSK Investigational Site Paris Cedex 20, France, 75970 Collapse << |
| NCT00866177 | - | - | Completed | - | - |
| NCT01938443 | Cancer | Phase 1 | Completed | - | France ... more >> GSK Investigational Site Villejuif Cedex, France, 94805 United Kingdom GSK Investigational Site London, United Kingdom, W12 0HS GSK Investigational Site London, United Kingdom, W1G 6AD GSK Investigational Site Newcastle upon Tyne, United Kingdom, NE7 7DN Collapse << |
| NCT00866177 | Recurrent Melanoma ... more >> Stage III Skin Melanoma Stage IV Skin Melanoma Collapse << | Phase 2 | Completed | - | United States, New York ... more >> Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 Collapse << |
| NCT00920140 | Cancer | Phase 2 | Completed | - | - |
| NCT00920140 | - | - | Completed | - | - |
| NCT02346032 | Biliary Tract Cancer | Phase 2 | Completed | - | - |
| NCT01943864 | Cancer | Phase 2 | Completed | - | Japan ... more >> GSK Investigational Site Chiba, Japan, 277-8577 GSK Investigational Site Osaka, Japan, 537-8511 GSK Investigational Site Shizuoka, Japan, 411-8777 GSK Investigational Site Tokyo, Japan, 104-0045 GSK Investigational Site Tokyo, Japan, 181-8611 Collapse << |
| NCT01146756 | Non Small Cell Lung Cancer | Phase 1 | Completed | - | United Kingdom ... more >> The Christie NHS Foundation Trust Manchester, Greater Manchester, United Kingdom, M20 4BX Collapse << |
| NCT02041481 | Recurrent Colon Cancer ... more >> Recurrent Rectal Cancer Stage IVA Colon Cancer Stage IVA Rectal Cancer Stage IVB Colon Cancer Stage IVB Rectal Cancer Collapse << | Phase 1 | Completed | - | United States, California ... more >> City of Hope Medical Center Duarte, California, United States, 91010 Collapse << |
| NCT02096471 | Neurofibromatosis Type 1 and G... more >>rowing or Symptomatic, Inoperable PN Collapse << | Phase 2 | Active, not recruiting | December 2018 | United States, California ... more >> Children's Hospital Los Angeles Los Angeles, California, United States, 90027 United States, District of Columbia Children's National Medical Center Washington, District of Columbia, United States, 20010 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637 United States, Indiana Indiana Unversity Indianapolis, Indiana, United States, 46202 United States, Maryland National Cancer Institute (NCI) Bethesda, Maryland, United States, 20892 United States, Massachusetts Children's Hospital Boston Boston, Massachusetts, United States, 02115 United States, Missouri Washington University - St. Louis Saint Louis, Missouri, United States, 63110 United States, New York New York University Medical Center New York, New York, United States, 10016 United States, Ohio Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19096 United States, Utah University of Utah Salt Lake City, Utah, United States, 84132 Collapse << |
| NCT01943864 | - | - | Completed | - | - |
| NCT01726738 | Stage III Melanoma ... more >> Stage IV Melanoma Unresectable Melanoma BRAF Mutant Melanoma Collapse << | Phase 2 | Completed | - | United States, North Carolina ... more >> Lineberger Comprehensive Cancer Center, University of North Carolina Chapel Hill, North Carolina, United States, 27599 Collapse << |
| NCT02049801 | Adult Acute Minimally Differen... more >>tiated Myeloid Leukemia (M0) Adult Acute Monoblastic Leukemia (M5a) Adult Acute Monocytic Leukemia (M5b) Adult Acute Myeloblastic Leukemia With Maturation (M2) Adult Acute Myeloblastic Leukemia Without Maturation (M1) Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities Adult Acute Myeloid Leukemia With Del(5q) Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) Adult Acute Myelomonocytic Leukemia (M4) Adult Erythroleukemia (M6a) Adult Pure Erythroid Leukemia (M6b) Recurrent Adult Acute Myeloid Leukemia Collapse << | Phase 1 | Terminated(logistics) | - | United States, California ... more >> Stanford University, School of Medicine Stanford, California, United States, 94305 Collapse << |
| NCT03455764 | Melanoma | Phase 1 Phase 2 | Recruiting | September 30, 2025 | United States, Massachusetts ... more >> Dana Farber Cancer Institute Recruiting Boston, Massachusetts, United States, 02215 Contact: Jennifer A Maattala 617-632-3992 jennifera_maattala@dfci.harvard.edu Principal Investigator: Elizabeth I Buchbinder, MD Collapse << |
| NCT03543969 | Melanoma (Skin) ... more >> Skin Cancer Skin Melanoma Skin Carcinoma Collapse << | Early Phase 1 | Recruiting | September 2021 | United States, Florida ... more >> H. Lee Moffitt Cancer Center and Research Institute Recruiting Tampa, Florida, United States, 33612 Contact: Leticia Tetteh 813-745-4617 leticia.tetteh@moffitt.org Principal Investigator: Zeynep Eroglu, M.D. Collapse << |
| NCT01701037 | - | - | Terminated(PI leaving VICC, lo... more >>w future accrual predicted, continued funding improbable,) Collapse << | - | - |
| NCT03743298 | Metastatic Melanoma | Phase 1 | Not yet recruiting | January 2023 | - |
| NCT03566485 | Stage III Breast Cancer ... more >> Stage IIIA Breast Cancer Stage IIIB Breast Cancer Stage IIIC Breast Cancer Stage IV Breast Cancer Estrogen Receptor-positive HER2/Neu Negative Collapse << | Phase 1 Phase 2 | Recruiting | July 2024 | United States, Tennessee ... more >> Vanderbilt-Ingram Cancer Center Recruiting Nashville, Tennessee, United States, 3720932 Contact: Clinical Trials Information Program 800-811-8480 cip@vanderbilt.edu Principal Investigator: Ingrid Mayer, MD Collapse << |
| NCT03101254 | Melanoma | Phase 1 Phase 2 | Recruiting | October 30, 2023 | United States, Massachusetts ... more >> Dana Farber Cancer Institute Recruiting Boston, Massachusetts, United States, 02215 Contact: Elizabeth Buchcinder, MD 617-632-5055 Principal Investigator: Elizabeth Buchbinder, MD Collapse << |
| NCT02418000 | AML MDS ... more >> CMML Collapse << | Phase 1 Phase 2 | Terminated(Insufficient effica... more >>cy in Phase 1 dose-escalation portion of study) Collapse << | - | United States, Colorado ... more >> Colorado Blood Cancer Institute Denver, Colorado, United States, 80218 United States, Florida H. Lee Moffitt Cancer Center & research Institute Tampa, Florida, United States, 33612 United States, Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Texas Transplant Institute San Antonio, Texas, United States, 78229 Collapse << |
| NCT01701037 | Recurrent Melanoma ... more >> Stage IIB Melanoma (Locally Advanced) Stage IIC Melanoma (Locally Advanced) Stage IIIA Melanoma Stage IIIB Melanoma Stage IIIC Melanoma Stage IV Melanoma (Limited, Resectable) Collapse << | Phase 2 | Terminated(PI leaving VICC, lo... more >>w future accrual predicted, continued funding improbable,) Collapse << | - | United States, Tennessee ... more >> Vanderbilt-Ingram Cancer Center Nashville, Tennessee, United States, 37232-6838 Collapse << |
| NCT01362803 | Neurofibromatosis 1 ... more >> Neurofibromatosis Type 1 NF 1 Neurofibroma, Plexiform Collapse << | Phase 1 Phase 2 | Active, not recruiting | July 2, 2024 | United States, District of Col... more >>umbia Childrens National Medical Center Washington, District of Columbia, United States, 20010 United States, Maryland National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 United States, Ohio Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229-3039 United States, Pennsylvania Childrens Hospital, Philadelphia Philadelphia, Pennsylvania, United States, 19104 Collapse << |
| NCT02194829 | Metastatic Pancreatic Adenocar... more >>cinoma Stage III Pancreatic Cancer AJCC v6 and v7 Stage IV Pancreatic Cancer AJCC v6 and v7 Unresectable Pancreatic Carcinoma Collapse << | Phase 1 Phase 2 | Active, not recruiting | - | United States, Illinois ... more >> Northwestern University Chicago, Illinois, United States, 60611 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Pennsylvania University of Pennsylvania/Abramson Cancer Center Philadelphia, Pennsylvania, United States, 19104 Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111 United States, Tennessee Vanderbilt University/Ingram Cancer Center Nashville, Tennessee, United States, 37232 Collapse << |
| NCT01820364 | - | - | Terminated(Study was withdrawn... more >> due to scientific and business considerations.) Collapse << | - | - |
| NCT01476137 | Cancer | Phase 1 | Completed | - | United States, Texas ... more >> GSK Investigational Site Dallas, Texas, United States, 75246 GSK Investigational Site San Antonio, Texas, United States, 78229 Collapse << |
| NCT01764828 | Neoplasms | Phase 1 | Completed | - | China ... more >> Shanghai, China, 200032 Japan Kashiwa, Chiba, Japan, 277-8577 Korea, Republic of Seoul, Korea, Republic of, 03080 Collapse << |
| NCT01820364 | Melanoma | Phase 2 | Terminated(Study was withdrawn... more >> due to scientific and business considerations.) Collapse << | - | United States, Tennessee ... more >> Sarah Cannon Research Institute Onc Dept Nashville, Tennessee, United States, 37203 Australia, Victoria Novartis Investigative Site East Melbourne, Victoria, Australia, 3002 Canada, Alberta Novartis Investigative Site Edmonton, Alberta, Canada, T6G 1Z2 Germany Novartis Investigative Site Heidelberg, Germany, 69120 Spain Novartis Investigative Site Barcelona, Catalunya, Spain, 08035 Switzerland Novartis Investigative Site Zuerich, Switzerland, 8091 Collapse << |
| NCT01277718 | - | - | Completed | - | - |
| NCT02834364 | Relapsed or Refractory Multipl... more >>e Myeloma Patients With BRAFV600 E or BRAFV600K Mutation Collapse << | Phase 2 | Recruiting | March 2021 | Germany ... more >> Mediz. Klinik und Poliklinik 1, Universitätsklinikum Dresden Not yet recruiting Dresden, Germany, 01307 Contact: Karolin Trautmann-Grill, Dr. Contact: Christoph Roelling, Dr. Universitätsklinikum Frankfurt, Medizinische Klinik II Not yet recruiting Frankfurt/Main, Germany, D-60590 Contact: Ivana von Metzler, Dr. med. ivana.metzler@kgu.de University Hospital Heidelberg, Med. Klinik V Recruiting Heidelberg, Germany, D-69120 Contact: GMMG Study Office studiensekretariat.gmmg@med.uni-heidelberg.de Principal Investigator: Marc Raab, PD. Dr. Universitätsklinikum Köln, Klinik I Innere Medizin Not yet recruiting Köln, Germany, D-50937 Contact: Christof Scheid, Prof. Dr. 0049-221-478-6296 c.scheid@uni-koeln.de Universitätsklinikum Tübingen, Medizinische Klinik II Recruiting Tübingen, Germany, D-72076 Contact: Katja Weisel, Prof. Dr. med. 0049-7071-29-82711 katja.weisel@med.uni-tuebingen.de Universitätsklinikum Würzburg, Medizinische Klinik und Poliklinik II Recruiting Würzburg, Germany, D-97080 Contact: Mannik Chatterjee, Dr. med. +49 (931) 201-40431 chatterjee_m@ukw.de Collapse << |
| NCT01277718 | Healthy Volunteer | Phase 1 | Completed | - | - |
| NCT01859026 | Lung Cancer N... more >>on-Small Cell Lung Cancer Collapse << | Phase 1 | Recruiting | March 31, 2020 | United States, Florida ... more >> H. Lee Moffitt Cancer Center and Research Institute Recruiting Tampa, Florida, United States, 33612 Contact: Germaine Gonzalez-Vazquez 813-745-6636 germaine.gonzalezvazquez@moffitt.org Sub-Investigator: Scott Antonia, M.D. Sub-Investigator: Eric Haura, M.D. Sub-Investigator: Charles Williams, M.D. Principal Investigator: Jhanelle Gray, M.D. Sub-Investigator: Tawee Tanvetyanon, M.D. Collapse << |
| NCT02322853 | Postmenopausal ... more >> Metastatic Breast Cancer Collapse << | Phase 2 | Terminated(lack of recruitment... more >>) Collapse << | - | France ... more >> Institut Bergonié Bordeaux, France Centre François Baclesse Caen, France Centre Jean Perrin Clermont -Ferrand, France Centre Georges-François Leclerc Dijon, France Centre Léon Bérard Lyon, France Institut Paoli Calmettes Marseille, France Institut de Cancérologie de l'Ouest Nantes, France Hegp, Ap-Hp Paris, France Hôpital St Louis, AP-HP Paris, France Centre Eugène Marquis Rennes, France Centre Henri Becquerel Rouen, France Institut Curie St Cloud, France Institut Claudius Regaud Toulouse, France Institut Gustave Roussy Villejuif, France Collapse << |
| NCT02281760 | BRAF V600E Mutation | Phase 2 | Completed | - | United States, Maryland ... more >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Collapse << |
| NCT01160718 | Breast Cancer | Phase 2 | Completed | - | Belgium ... more >> Universitair Ziekenhuis Gent Ghent, Belgium, B-9000 U.Z. Gasthuisberg Leuven, Belgium, B-3000 Switzerland Kantonsspital Aarau Aarau, Switzerland, CH-5001 Kantonsspital Baden Baden, Switzerland, CH-5404 Universitaetsspital-Basel Basel, Switzerland, CH-4031 Inselspital Bern Bern, Switzerland, CH-3010 Spitalzentrum Biel Biel, Switzerland, CH-2501 Kantonsspital Graubuenden Chur, Switzerland, CH-7000 Brustzentrum Thurgau at Kantonsspital Frauenfeld Frauenfeld, Switzerland, 8501 Centre Hospitalier Universitaire Vaudois Lausanne, Switzerland, CH-1011 Kantonsspital Luzern Luzerne, Switzerland, CH-6000 Oncology Institute of Southern Switzerland - Mendrisio Mendrisio, Switzerland, CH-6850 Hopital de Morges Morges, Switzerland, CH-1110 Kantonsspital - St. Gallen St. Gallen, Switzerland, CH-9007 Hopitaux Universitaires de Geneve Thonex-Geneve, Switzerland, CH-1226 Kantonsspital Winterthur Winterthur, Switzerland, CH-8400 City Hospital Triemli Zurich, Switzerland, CH-8063 Collapse << |
| NCT02382549 | Melanoma | Phase 1 Phase 2 | Recruiting | June 2020 | United States, Virginia ... more >> Cancer Center at the University of Virginia Recruiting Charlottesville, Virginia, United States, 22908 Collapse << |
| NCT03244956 | Metastatic Radioactive Iodine ... more >>Refractory Thyroid Cancer Patients With RAS or BRAF Mutation Collapse << | Phase 2 | Recruiting | August 2022 | France ... more >> Gustave Roussy Recruiting Villejuif, Val De Marne, France, 94805 Contact: Sophie LEBOULLEUX, MD 0142114257 ext +33 sophie.leboulleux@gustaveroussy.fr Contact: Isabelle BORGET, MD 0142114146 ext +33 isabelle.borget@gustaveroussy.fr Collapse << |
| NCT02101788 | Low Grade Ovarian Serous Adeno... more >>carcinoma Micropapillary Serous Carcinoma Ovarian Serous Adenocarcinoma Primary Peritoneal Serous Adenocarcinoma Recurrent Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Collapse << | Phase 2 Phase 3 | Active, not recruiting | - | - |
| NCT03109301 | Neoplasms, Nerve Tissue ... more >> Neurofibromatosis 1 Heredodegenerative Disorders, Nervous System Peripheral Nervous System Diseases Collapse << | Phase 2 | Recruiting | February 1, 2023 | United States, Maryland ... more >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office 888-624-1937 Collapse << |
| NCT01827384 | Advanced Malignant Solid Neopl... more >>asm Collapse << | Not Applicable | Suspended(Scheduled Interim Mo... more >>nitoring) Collapse << | - | United States, Colorado ... more >> University of Colorado Hospital Aurora, Colorado, United States, 80045 United States, Kentucky University of Kentucky/Markey Cancer Center Lexington, Kentucky, United States, 40536 United States, Maryland National Cancer Institute Developmental Therapeutics Clinic Bethesda, Maryland, United States, 20892 United States, Missouri Washington University School of Medicine Saint Louis, Missouri, United States, 63110 United States, New Jersey Rutgers Cancer Institute of New Jersey New Brunswick, New Jersey, United States, 08903 United States, Pennsylvania University of Pittsburgh Cancer Institute (UPCI) Pittsburgh, Pennsylvania, United States, 15232 United States, Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT03416933 | Melanoma (Skin) | Not Applicable | Recruiting | April 2021 | France ... more >> Hôpital de Mercy Not yet recruiting Ars-Laquenexy, France, 57 245 Contact: Truchetet François, MD Contact: Muller Philippe Co-, MD CHRU Nancy Recruiting Vandœuvre-lès-Nancy, France, 54 511 Contact: Granel-Brocard Florence, MD Contact: Schmutz Jean-Luc, MD Institut de Cancérologie de Lorraine (ICL) Recruiting Vandœuvre-lès-Nancy, France Contact: Geoffrois Lionnel, MD l.geoffrois@nancy.unicancer.fr Contact: Harlé Alexandre, PharmaD a.harle@nancy.unicancer.fr Collapse << |
| NCT01938456 | Lung Cancer, Non-Small Cell | Phase 1 | Withdrawn(This study was Cance... more >>lled Before Active) Collapse << | July 2014 | - |
| NCT02465060 | Advanced Malignant Solid Neopl... more >>asm Bladder Carcinoma Breast Carcinoma Cervical Carcinoma Colon Carcinoma Colorectal Carcinoma Endometrial Carcinoma Esophageal Carcinoma Gastric Carcinoma Glioma Head and Neck Carcinoma Kidney Carcinoma Liver and Intrahepatic Bile Duct Carcinoma Lung Carcinoma Lymphoma Malignant Uterine Neoplasm Melanoma Ovarian Carcinoma Pancreatic Carcinoma Plasma Cell Myeloma Prostate Carcinoma Rectal Carcinoma Recurrent Bladder Carcinoma Recurrent Breast Carcinoma Recurrent Cervical Carcinoma Recurrent Colon Carcinoma Recurrent Colorectal Carcinoma Recurrent Esophageal Carcinoma Recurrent Gastric Carcinoma Recurrent Glioma Recurrent Head and Neck Carcinoma Recurrent Liver Carcinoma Recurrent Lung Carcinoma Recurrent Lymphoma Recurrent Malignant Solid Neoplasm Recurrent Melanoma Recurrent Ovarian Carcinoma Recurrent Pancreatic Carcinoma Recurrent Plasma Cell Myeloma Recurrent Prostate Carcinoma Recurrent Rectal Carcinoma Recurrent Skin Carcinoma Recurrent Thyroid Gland Carcinoma Recurrent Uterine Corpus Carcinoma Refractory Lymphoma Refractory Malignant Solid Neoplasm Refractory Plasma Cell Myeloma Skin Carcinoma Thyroid Gland Carcinoma Uterine Corpus Cancer Collapse << | Phase 2 | Recruiting | - | - |
| NCT02292732 | Cancer | Phase 1 | Withdrawn | May 2017 | - |
| NCT02152995 | BRAF Gene Mutation ... more >> Poorly Differentiated Thyroid Gland Carcinoma RAS Family Gene Mutation Recurrent Thyroid Gland Carcinoma Stage IV Thyroid Gland Follicular Carcinoma AJCC v7 Stage IV Thyroid Gland Papillary Carcinoma AJCC v7 Stage IVA Thyroid Gland Follicular Carcinoma AJCC v7 Stage IVA Thyroid Gland Papillary Carcinoma AJCC v7 Stage IVB Thyroid Gland Follicular Carcinoma AJCC v7 Stage IVB Thyroid Gland Papillary Carcinoma AJCC v7 Stage IVC Thyroid Gland Follicular Carcinoma AJCC v7 Stage IVC Thyroid Gland Papillary Carcinoma AJCC v7 Collapse << | Phase 2 | Recruiting | - | United States, New York ... more >> Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Alan L. Ho 646-888-4235 hoa@mskcc.org Principal Investigator: Alan L. Ho Collapse << |
| NCT02224781 | BRAF NP_004324.2:p.V600X ... more >> Metastatic Melanoma Recurrent Melanoma Stage III Cutaneous Melanoma AJCC v7 Stage IIIA Cutaneous Melanoma AJCC v7 Stage IIIB Cutaneous Melanoma AJCC v7 Stage IIIC Cutaneous Melanoma AJCC v7 Stage IV Cutaneous Melanoma AJCC v6 and v7 Collapse << | Phase 3 | Recruiting | - | - |
| NCT02510001 | Solid Tumor C... more >>olorectal Cancer Collapse << | Phase 1 | Active, not recruiting | September 2019 | United Kingdom ... more >> Oxford University Hospital NHS Trust Oxford, United Kingdom, OX3 7LE Collapse << |
| NCT01912625 | KRAS Activating Mutation ... more >> Recurrent Non-Small Cell Lung Carcinoma Stage III Non-Small Cell Lung Cancer AJCC v7 Stage IIIA Non-Small Cell Lung Cancer AJCC v7 Stage IIIB Lung Non-Small Cell Cancer AJCC v7 Collapse << | Phase 1 | Active, not recruiting | - | United States, Minnesota ... more >> Mayo Clinic Rochester, Minnesota, United States, 55905 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43210 United States, Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 United States, Wisconsin University of Wisconsin Hospital and Clinics Madison, Wisconsin, United States, 53792 Collapse << |
