|((S)-4-甲基-1-(((S)-4-甲基-1-(((S)-4-甲基-1-氧代戊烷-2-基)氨基)-1-氧代戊烷-2-基)氨基)-1-氧代戊烷-2-基)氨基甲酸苄酯|CsnPharm

CAS No.: 133407-82-6

MG-132 Catalog No. CSN11436

Synonyms: Z-Leu-Leu-Leu-al;Z-Leu-Leu-Leu-CHO

MG-132 is an inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 nM).

规格	价格	促销价格	库存	数量

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

加入购物车大规格询价

加入收藏

产品咨询

400-920-2911

sales@csnpharm.cn

tech@csnpharm.cn

纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

靶点 Calpain

IC50:1.2μM
描述Proteasome and calpain are the main nonlysosomal proteases responsible for intracellular proteolysis. MG-132 is a potent cell-permeable inhibitor of both proteasome and calpain with respective IC50 values of 0.1µM and 1.25µM. MG-132 induced neurite outgrowth in PC12 cells at a concentration of 20nM. In rabbit erythrocytes, MG-132 penetrated cell membrane and inhibited the autolysis at the dose of 100µM^[3]. MG-132 also showed inhibitory activity on cell growth in both human ocular melanoma IPC227F cells and murine melanoma B16 cells with IC50 values of 42 and 77nM, respectively^[4]. In airway epithelial cells, pretreatment with 10μM MG-132 for 1h inhibited TNF-α-stimulated IL-8 protein production and release. Moreover, preincubation of cells with 10μM MG-132 reversed the effects of TNF-α on the transcriptional activity of IL-8 gene, IκB degradation, and NF-κB activation^[5]. In mice with hindlimb immobilization, twice-daily subcutaneous injections of MG-132 (7.5 mg/kg/dose) significantly increased the running time on treadmill as compared to DMSO-treated group. However, no significant difference in the running time of MG132- and DMSO-treated mice was observed after 11 days of remobilization^[6].
作用机制MG-132 inhibits proteasome primarily via acting on the chymotrypsin-like site in the  subunit. It also inhibits the caspase-like site at high concentrations^[7].
细胞研究

Cell Data

Cell Lines	Concentration	Assay Type	Time	Activity Description	Data Sources
293T	10 μM	Cytotoxic Assay	72 h	IC50<2 μM	24625088
293T	10 μM	Function Assay	24 h	Moderately induces heat-shock	24625088
697	-	Growth Inhibition Assay	-	IC50=14.4511 μM	SANGER

更多
动物研究
剂量
Rat: 0.5 mg/kg - 12.5 mg/kg^[3] (i.p.) Mice: 1 mg/kg^[4] (i.v.), 0.03 mg/kg - 0.1 mg/kg^[5] (BALB/c Mice, i.p.), 0.04 mg/kg - 30 mg/kg^[6] (i.v., i.p.)

给药途径
i.p., i.v.
参考文献

动物研究
剂量	Rat: 0.5 mg/kg - 12.5 mg/kg^[3] (i.p.) Mice: 1 mg/kg^[4] (i.v.), 0.03 mg/kg - 0.1 mg/kg^[5] (BALB/c Mice, i.p.), 0.04 mg/kg - 30 mg/kg^[6] (i.v., i.p.)
给药途径	i.p., i.v.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.1025 mL
- 10.5126 mL
- 21.0252 mL
- 5 mM
- 0.4205 mL
- 2.1025 mL
- 4.2050 mL
- 10 mM
- 0.2103 mL
- 1.0513 mL
- 2.1025 mL

技术信息

CAS号

133407-82-6

储存条件

粉末: Inert atmosphere,Store in freezer, under -20°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C26H41N3O5

运输

蓝冰

分子量

475.62

别名

Z-Leu-Leu-Leu-al;Z-Leu-Leu-Leu-CHO

溶解度

DMSO	600.0 mg/mL (1261.5 mM) warming
Water	insoluble

动物实验配方

IP	2% DMSO+2% Tween80+40% PEG300+water	6 mg/mL	clear
PO	0.5% CMC-Na	15 mg/mL	suspension

大规格询价

号为必填项

姓名: 邮箱: 手机号:

留言:

提交

Cell Lines	Concentration	Assay Type	Time	Activity Description	Data Sources

293T	10 μM	Cytotoxic Assay	72 h	IC50<2 μM	24625088
293T	10 μM	Function Assay	24 h	Moderately induces heat-shock	24625088
697	-	Growth Inhibition Assay	-	IC50=14.4511 μM	SANGER
8-MG-BA	-	Growth Inhibition Assay	-	IC50=0.39837 μM	SANGER
A101D	-	Growth Inhibition Assay	-	IC50=0.03279 μM	SANGER
A253	-	Growth Inhibition Assay	-	IC50=0.16128 μM	SANGER
A2780 cDDP	-	Apoptosis Assay	24 h	Induces apoptosis by inhibiting PTEN degradation	17684018
A388	-	Growth Inhibition Assay	-	IC50=0.09065 μM	SANGER
A3-KAW	-	Growth Inhibition Assay	-	IC50=49.8061 μM	SANGER
A498	-	Growth Inhibition Assay	-	IC50=12.7069 μM	SANGER
A4-Fuk	-	Growth Inhibition Assay	-	IC50=6.08118 μM	SANGER
A-549	40 μM	Cytotoxic Assay	48 h	IC50<10 μM	24697496
A704	-	Growth Inhibition Assay	-	IC50=0.48692 μM	SANGER
ACN	-	Growth Inhibition Assay	-	IC50=0.22638 μM	SANGER
ALL-PO	-	Growth Inhibition Assay	-	IC50=5.63795 μM	SANGER
AM-38	-	Growth Inhibition Assay	-	IC50=12.5633 μM	SANGER
ARH-77	-	Growth Inhibition Assay	-	IC50=5.67087 μM	SANGER
ATN-1	-	Growth Inhibition Assay	-	IC50=74.505 μM	SANGER
BB30-HNC	-	Growth Inhibition Assay	-	IC50=1.72685 μM	SANGER
BB49-HNC	-	Growth Inhibition Assay	-	IC50=0.49096 μM	SANGER
BB65-RCC	-	Growth Inhibition Assay	-	IC50=0.56811 μM	SANGER
BC-1	-	Growth Inhibition Assay	-	IC50=5.00447 μM	SANGER
BC-3	-	Growth Inhibition Assay	-	IC50=15.398 μM	SANGER
BE-13	-	Growth Inhibition Assay	-	IC50=134.044 μM	SANGER
Becker	-	Growth Inhibition Assay	-	IC50=0.79621 μM	SANGER
BL-41	-	Growth Inhibition Assay	-	IC50=0.06947 μM	SANGER
BL-70	-	Growth Inhibition Assay	-	IC50=0.69388 μM	SANGER
BOKU	-	Growth Inhibition Assay	-	IC50=15.9608 μM	SANGER
BT-474	-	Growth Inhibition Assay	-	IC50=5.23102 μM	SANGER
BV-173	-	Growth Inhibition Assay	-	IC50=108.728 μM	SANGER
C2BBe1	-	Growth Inhibition Assay	-	IC50=0.27907 μM	SANGER
C8166	-	Growth Inhibition Assay	-	IC50=345.338 μM	SANGER
CA46	-	Growth Inhibition Assay	-	IC50=10.361 μM	SANGER
CAL-148	-	Growth Inhibition Assay	-	IC50=17.9796 μM	SANGER
Calu6	10 μM	Function Assay	18 h	Significantly accumulates frataxin precursor	23506486
Calu-6	-	Growth Inhibition Assay	-	IC50=5.622 μM	SANGER
CAS-1	-	Growth Inhibition Assay	-	IC50=0.15482 μM	SANGER
CCRF-CEM	-	Growth Inhibition Assay	-	IC50=0.47674 μM	SANGER
CESS	-	Growth Inhibition Assay	-	IC50=0.1706 μM	SANGER
CGTH-W-1	-	Growth Inhibition Assay	-	IC50=36.9048 μM	SANGER
CHP-126	-	Growth Inhibition Assay	-	IC50=21.6181 μM	SANGER
CMK	-	Growth Inhibition Assay	-	IC50=0.3112 μM	SANGER
COLO-320-HSR	-	Growth Inhibition Assay	-	IC50=3.75634 μM	SANGER
COLO-668	-	Growth Inhibition Assay	-	IC50=81.5884 μM	SANGER
COLO-684	-	Growth Inhibition Assay	-	IC50=0.90658 μM	SANGER
COLO-800	-	Growth Inhibition Assay	-	IC50=28.2956 μM	SANGER
COLO-824	-	Growth Inhibition Assay	-	IC50=14.7994 μM	SANGER
COLO-829	-	Growth Inhibition Assay	-	IC50=0.24257 μM	SANGER
COR-L279	-	Growth Inhibition Assay	-	IC50=26.7922 μM	SANGER
COR-L88	-	Growth Inhibition Assay	-	IC50=12.9382 μM	SANGER
COS-7	10 μM	Cytotoxic Assay	-	IC50<10 μM	18088097
CP66-MEL	-	Growth Inhibition Assay	-	IC50=0.075 μM	SANGER
CP67-MEL	-	Growth Inhibition Assay	-	IC50=0.2673 μM	SANGER
CPC-N	-	Growth Inhibition Assay	-	IC50=24.0201 μM	SANGER
CTB-1	-	Growth Inhibition Assay	-	IC50=0.77955 μM	SANGER
CTV-1	-	Growth Inhibition Assay	-	IC50=10.0979 μM	SANGER
CW-2	-	Growth Inhibition Assay	-	IC50=44.8342 μM	SANGER
D-247MG	-	Growth Inhibition Assay	-	IC50=0.07209 μM	SANGER
D-263MG	-	Growth Inhibition Assay	-	IC50=0.16006 μM	SANGER
D-283MED	-	Growth Inhibition Assay	-	IC50=8.91719 μM	SANGER
D-336MG	-	Growth Inhibition Assay	-	IC50=4.01166 μM	SANGER
D-392MG	-	Growth Inhibition Assay	-	IC50=0.19115 μM	SANGER
D-502MG	-	Growth Inhibition Assay	-	IC50=1.67211 μM	SANGER
D-542MG	-	Growth Inhibition Assay	-	IC50=0.05957 μM	SANGER
Daudi	-	Growth Inhibition Assay	-	IC50=18.9231 μM	SANGER
DB	-	Growth Inhibition Assay	-	IC50=13.9885 μM	SANGER
DEL	-	Growth Inhibition Assay	-	IC50=41.4405 μM	SANGER
DG-75	-	Growth Inhibition Assay	-	IC50=113.352 μM	SANGER
DJM-1	-	Growth Inhibition Assay	-	IC50=2.02552 μM	SANGER
DMS-114	-	Growth Inhibition Assay	-	IC50=1.44539 μM	SANGER
DMS-153	-	Growth Inhibition Assay	-	IC50=121.745 μM	SANGER
DMS-79	-	Growth Inhibition Assay	-	IC50=117.382 μM	SANGER
DOHH-2	-	Growth Inhibition Assay	-	IC50=74.9514 μM	SANGER
DSH1	-	Growth Inhibition Assay	-	IC50=0.05289 μM	SANGER
DU-4475	-	Growth Inhibition Assay	-	IC50=0.19658 μM	SANGER
EB2	-	Growth Inhibition Assay	-	IC50=13.8505 μM	SANGER
EB-3	-	Growth Inhibition Assay	-	IC50=5.03041 μM	SANGER
ECC12	-	Growth Inhibition Assay	-	IC50=2.3794 μM	SANGER
ECC4	-	Growth Inhibition Assay	-	IC50=93.8269 μM	SANGER
EC-GI-10	-	Growth Inhibition Assay	-	IC50=10.7031 μM	SANGER
EHEB	-	Growth Inhibition Assay	-	IC50=21.6731 μM	SANGER
EKVX	-	Growth Inhibition Assay	-	IC50=1.03442 μM	SANGER
EM-2	-	Growth Inhibition Assay	-	IC50=6.67099 μM	SANGER
EoL-1-	-	Growth Inhibition Assay	-	IC50=44.1568 μM	SANGER
ES1	-	Growth Inhibition Assay	-	IC50=1.07921 μM	SANGER
ES3	-	Growth Inhibition Assay	-	IC50=4.32824 μM	SANGER
ES4	-	Growth Inhibition Assay	-	IC50=3.06111 μM	SANGER
ES5	-	Growth Inhibition Assay	-	IC50=4.40255 μM	SANGER
ES6	-	Growth Inhibition Assay	-	IC50=0.01306 μM	SANGER
ES7	-	Growth Inhibition Assay	-	IC50=0.8965 μM	SANGER
ES8	-	Growth Inhibition Assay	-	IC50=0.24763 μM	SANGER
ETK-1	-	Growth Inhibition Assay	-	IC50=28.3446 μM	SANGER
EVSA-T	-	Growth Inhibition Assay	-	IC50=0.49911 μM	SANGER
EW-1	-	Growth Inhibition Assay	-	IC50=0.21047 μM	SANGER
EW-11	-	Growth Inhibition Assay	-	IC50=11.5186 μM	SANGER
EW-12	-	Growth Inhibition Assay	-	IC50=144.699 μM	SANGER
EW-13	-	Growth Inhibition Assay	-	IC50=33.8969 μM	SANGER
EW-16	-	Growth Inhibition Assay	-	IC50=1.31347 μM	SANGER
EW-18	-	Growth Inhibition Assay	-	IC50=2.02337 μM	SANGER
EW-22	-	Growth Inhibition Assay	-	IC50=106.19 μM	SANGER
EW-24	-	Growth Inhibition Assay	-	IC50=32.3474 μM	SANGER
EW-3	-	Growth Inhibition Assay	-	IC50=94.9081 μM	SANGER
GAK	-	Growth Inhibition Assay	-	IC50=0.20534 μM	SANGER
GB-1	-	Growth Inhibition Assay	-	IC50=0.72124 μM	SANGER
GCIY	-	Growth Inhibition Assay	-	IC50=5.47236 μM	SANGER
GDM-1	-	Growth Inhibition Assay	-	IC50=0.35104 μM	SANGER
GI-1	-	Growth Inhibition Assay	-	IC50=1.47131 μM	SANGER
GI-ME-N	-	Growth Inhibition Assay	-	IC50=0.19306 μM	SANGER
GOTO	-	Growth Inhibition Assay	-	IC50=16.9617 μM	SANGER
GR-ST	-	Growth Inhibition Assay	-	IC50=21.417 μM	SANGER
GT3TKB	-	Growth Inhibition Assay	-	IC50=5.17662 μM	SANGER
HAL-01	-	Growth Inhibition Assay	-	IC50=4.57034 μM	SANGER
HC-1	-	Growth Inhibition Assay	-	IC50=1.3817 μM	SANGER
HCC1187	-	Growth Inhibition Assay	-	IC50=77.6122 μM	SANGER
HCC1599	-	Growth Inhibition Assay	-	IC50=74.8732 μM	SANGER
HCC2157	-	Growth Inhibition Assay	-	IC50=17.4755 μM	SANGER
HCC2218	-	Growth Inhibition Assay	-	IC50=3.46937 μM	SANGER
HCC2998	-	Growth Inhibition Assay	-	IC50=0.93854 μM	SANGER
HCE-4	-	Growth Inhibition Assay	-	IC50=1.30221 μM	SANGER
HCE-T	-	Growth Inhibition Assay	-	IC50=2.44883 μM	SANGER
HDLM-2	-	Growth Inhibition Assay	-	IC50=20.8821 μM	SANGER
HD-MY-Z	-	Growth Inhibition Assay	-	IC50=0.23303 μM	SANGER
HEK-293	2 and 20 μM	Kinase Assay	2 h	Inhibits ChT-L activity with IC50 of 9 nM	23540790
HEL	-	Growth Inhibition Assay	-	IC50=0.18517 μM	SANGER
HeLa	10 μM	Kinase Assay	1 h	Induces PARP cleavage by inhibiting proseasome activity	24321833
Hepa-1c1c7	25 μM	Function Assay	6 h	Increases Nrf2 protein level	20392544
HH	-	Growth Inhibition Assay	-	IC50=0.32897 μM	SANGER
HL-60	40 μM	Cytotoxic Assay	48 h	IC50<10 μM	24697496
HL-60	-	Growth Inhibition Assay	-	IC50=20.1965 μM	SANGER
HOP-62	-	Growth Inhibition Assay	-	IC50=0.10949 μM	SANGER
HT	-	Growth Inhibition Assay	-	IC50=45.7007 μM	SANGER
HT-144	-	Growth Inhibition Assay	-	IC50=0.13895 μM	SANGER
HuH-7	10 μM	Cytotoxic Assay	-	IC50<10 μM	18088097
HUTU-80	-	Growth Inhibition Assay	-	IC50=6.36897 μM	SANGER
IA-LM	-	Growth Inhibition Assay	-	IC50=1.24116 μM	SANGER
IFN-gamma-induced RAW264.7	-	Function Assay	-	Inhibits nitric oxide production with IC50 of 0.077 μM	22277277
IM-9	-	Growth Inhibition Assay	-	IC50=20.6224 μM	SANGER
IMR-5	-	Growth Inhibition Assay	-	IC50=181.571 μM	SANGER
IPC227F	1 μM	Cytotoxic Assay	48 h	IC50=0.077 μM	21924528
IST-MEL1	-	Growth Inhibition Assay	-	IC50=9.74198 μM	SANGER
IST-MES1	-	Growth Inhibition Assay	-	IC50=1.40208 μM	SANGER
IST-SL1	-	Growth Inhibition Assay	-	IC50=0.20094 μM	SANGER
IST-SL2	-	Growth Inhibition Assay	-	IC50=2.01252 μM	SANGER
JAR	-	Growth Inhibition Assay	-	IC50=31.3799 μM	SANGER
JiyoyeP-2003	-	Growth Inhibition Assay	-	IC50=9.29317 μM	SANGER
J-RT3-T3-5	-	Growth Inhibition Assay	-	IC50=19.4066 μM	SANGER
JVM-2	-	Growth Inhibition Assay	-	IC50=14.7735 μM	SANGER
JVM-3	-	Growth Inhibition Assay	-	IC50=1.93904 μM	SANGER
K052	-	Growth Inhibition Assay	-	IC50=0.2899 μM	SANGER
K5	-	Growth Inhibition Assay	-	IC50=12.9462 μM	SANGER
K-562	-	Growth Inhibition Assay	-	IC50=37.0864 μM	SANGER
KALS-1	-	Growth Inhibition Assay	-	IC50=0.46584 μM	SANGER
KARPAS-299	-	Growth Inhibition Assay	-	IC50=70.4447 μM	SANGER
KARPAS-422	-	Growth Inhibition Assay	-	IC50=12.7496 μM	SANGER
KARPAS-45	-	Growth Inhibition Assay	-	IC50=1.04016 μM	SANGER
KASUMI-1	-	Growth Inhibition Assay	-	IC50=6.84787 μM	SANGER
KE-37	-	Growth Inhibition Assay	-	IC50=0.13278 μM	SANGER
KG-1	-	Growth Inhibition Assay	-	IC50=2.88791 μM	SANGER
KGN	-	Growth Inhibition Assay	-	IC50=1.05045 μM	SANGER
KINGS-1	-	Growth Inhibition Assay	-	IC50=0.1479 μM	SANGER
KLE	-	Growth Inhibition Assay	-	IC50=0.31306 μM	SANGER
KM12	-	Growth Inhibition Assay	-	IC50=0.85466 μM	SANGER
KM-H2	-	Growth Inhibition Assay	-	IC50=2.29043 μM	SANGER
KMOE-2	-	Growth Inhibition Assay	-	IC50=19.6482 μM	SANGER
KMS-12-PE	-	Growth Inhibition Assay	-	IC50=3.67723 μM	SANGER
KNS-42	-	Growth Inhibition Assay	-	IC50=0.04441 μM	SANGER
KNS-81-FD	-	Growth Inhibition Assay	-	IC50=0.30323 μM	SANGER
KP-N-RT-BM-1	-	Growth Inhibition Assay	-	IC50=56.6638 μM	SANGER
KP-N-YN	-	Growth Inhibition Assay	-	IC50=34.9057 μM	SANGER
KP-N-YS	-	Growth Inhibition Assay	-	IC50=139.736 μM	SANGER
KS-1	-	Growth Inhibition Assay	-	IC50=0.06458 μM	SANGER
KU812	-	Growth Inhibition Assay	-	IC50=13.6124 μM	SANGER
KURAMOCHI	-	Growth Inhibition Assay	-	IC50=1.12374 μM	SANGER
KY821	-	Growth Inhibition Assay	-	IC50=91.6551 μM	SANGER
L-363	-	Growth Inhibition Assay	-	IC50=32.2144 μM	SANGER
L-428	-	Growth Inhibition Assay	-	IC50=34.7536 μM	SANGER
L-540	-	Growth Inhibition Assay	-	IC50=1.11839 μM	SANGER
LAMA-84	-	Growth Inhibition Assay	-	IC50=0.21851 μM	SANGER
LAN-6	-	Growth Inhibition Assay	-	IC50=0.313 μM	SANGER
LB1047-RCC	-	Growth Inhibition Assay	-	IC50=7.72231 μM	SANGER
LB2241-RCC	-	Growth Inhibition Assay	-	IC50=0.14247 μM	SANGER
LB2518-MEL	-	Growth Inhibition Assay	-	IC50=0.0376 μM	SANGER
LB373-MEL-D	-	Growth Inhibition Assay	-	IC50=0.24198 μM	SANGER
LB647-SCLC	-	Growth Inhibition Assay	-	IC50=4.56308 μM	SANGER
LB771-HNC	-	Growth Inhibition Assay	-	IC50=0.08036 μM	SANGER
LB831-BLC	-	Growth Inhibition Assay	-	IC50=0.1934 μM	SANGER
LB996-RCC	-	Growth Inhibition Assay	-	IC50=40.8716 μM	SANGER
LC-1F	-	Growth Inhibition Assay	-	IC50=1.55198 μM	SANGER
LC-2-ad	-	Growth Inhibition Assay	-	IC50=39.4337 μM	SANGER
LC4-1	-	Growth Inhibition Assay	-	IC50=0.43607 μM	SANGER
LNCaP-Clone-FGC	-	Growth Inhibition Assay	-	IC50=29.9281 μM	SANGER
LOUCY	-	Growth Inhibition Assay	-	IC50=0.25456 μM	SANGER
LOXIMVI	-	Growth Inhibition Assay	-	IC50=61.8266 μM	SANGER
LP-1	300 nM	Apoptosis Assay	24 h	Induces apoptosis by increasing cleaved PARP level and reducing Mcl-1 protein level	15958589
LP-1	-	Growth Inhibition Assay	-	IC50=4.72371 μM	SANGER
LPS-stimulated RAW264.7 cells	25 μM	Function Assay	-	Inhibits nitric oxide production with IC50 of 0.1 μM	24697496
LPS-stimulated RAW264.7 cells	-	Function Assay	-	Inhibits NF-kappaB DNA binding	17407277
LS-1034	-	Growth Inhibition Assay	-	IC50=17.6818 μM	SANGER
LS-123	-	Growth Inhibition Assay	-	IC50=24.9012 μM	SANGER
LS-411N	-	Growth Inhibition Assay	-	IC50=1.69807 μM	SANGER
LS-513	-	Growth Inhibition Assay	-	IC50=0.66751 μM	SANGER
LU-134-A	-	Growth Inhibition Assay	-	IC50=83.1351 μM	SANGER
LU-139	-	Growth Inhibition Assay	-	IC50=12.9026 μM	SANGER
LU-165	-	Growth Inhibition Assay	-	IC50=28.0861 μM	SANGER
LU-65	-	Growth Inhibition Assay	-	IC50=1.12753 μM	SANGER
LXF-289	-	Growth Inhibition Assay	-	IC50=0.07066 μM	SANGER
MC116	-	Growth Inhibition Assay	-	IC50=8.9794 μM	SANGER
MC-CAR	-	Growth Inhibition Assay	-	IC50=2.2295 μM	SANGER
MCF10A	1 μM	Growth Inhibition Assay	72 h	IC50=0.29 μM	24153206
MCF-7	40 μM	Cytotoxic Assay	48 h	IC50=7.3 μM	24697496
MCF-7	1 μM	Growth Inhibition Assay	72 h	IC50=0.13 μM	24153206
MDA-MB-134-VI	-	Growth Inhibition Assay	-	IC50=148.268 μM	SANGER
MDA-MB-231	1 μM	Growth Inhibition Assay	72 h	IC50=0.18 μM	24153206
MEG-01	-	Growth Inhibition Assay	-	IC50=3.5968 μM	SANGER
MFH-ino	-	Growth Inhibition Assay	-	IC50=1.17501 μM	SANGER
MFM-223	-	Growth Inhibition Assay	-	IC50=2.50871 μM	SANGER
MHH-CALL-2	-	Growth Inhibition Assay	-	IC50=70.06 μM	SANGER
MHH-NB-11	-	Growth Inhibition Assay	-	IC50=13.2902 μM	SANGER
MHH-PREB-1	-	Growth Inhibition Assay	-	IC50=39.7388 μM	SANGER
ML-2	-	Growth Inhibition Assay	-	IC50=0.11806 μM	SANGER
MLMA	-	Growth Inhibition Assay	-	IC50=41.7595 μM	SANGER
MMAC-SF	-	Growth Inhibition Assay	-	IC50=0.07268 μM	SANGER
MN-60	-	Growth Inhibition Assay	-	IC50=109.69 μM	SANGER
MOLT-16	-	Growth Inhibition Assay	-	IC50=0.29524 μM	SANGER
MOLT-4	-	Growth Inhibition Assay	-	IC50=18.8208 μM	SANGER
MONO-MAC-6	-	Growth Inhibition Assay	-	IC50=0.53611 μM	SANGER
Mo-T	-	Growth Inhibition Assay	-	IC50=0.51762 μM	SANGER
MPP-89	-	Growth Inhibition Assay	-	IC50=42.5875 μM	SANGER
MRK-nu-1	-	Growth Inhibition Assay	-	IC50=13.195 μM	SANGER
MS-1	-	Growth Inhibition Assay	-	IC50=239.121 μM	SANGER
MSTO-211H	-	Growth Inhibition Assay	-	IC50=14.7448 μM	SANGER
MV-4-11	-	Growth Inhibition Assay	-	IC50=42.9067 μM	SANGER
MZ1-PC	-	Growth Inhibition Assay	-	IC50=7.86558 μM	SANGER
MZ2-MEL	-	Growth Inhibition Assay	-	IC50=0.17559 μM	SANGER
MZ7-mel	-	Growth Inhibition Assay	-	IC50=0.26374 μM	SANGER
NALM-6	-	Growth Inhibition Assay	-	IC50=6.86754 μM	SANGER
NB1	-	Growth Inhibition Assay	-	IC50=24.6939 μM	SANGER
NB10	-	Growth Inhibition Assay	-	IC50=7.99556 μM	SANGER
NB12	-	Growth Inhibition Assay	-	IC50=3.59888 μM	SANGER
NB13	-	Growth Inhibition Assay	-	IC50=12.9783 μM	SANGER
NB14	-	Growth Inhibition Assay	-	IC50=147.082 μM	SANGER
NB17	-	Growth Inhibition Assay	-	IC50=0.4297 μM	SANGER
NB5	-	Growth Inhibition Assay	-	IC50=70.3468 μM	SANGER
NB6	-	Growth Inhibition Assay	-	IC50=30.9503 μM	SANGER
NB69	-	Growth Inhibition Assay	-	IC50=33.6454 μM	SANGER
NB7	-	Growth Inhibition Assay	-	IC50=95.7786 μM	SANGER
NCCIT	-	Growth Inhibition Assay	-	IC50=0.31783 μM	SANGER
NCI-H1092	-	Growth Inhibition Assay	-	IC50=0.38844 μM	SANGER
NCI-H1155	-	Growth Inhibition Assay	-	IC50=74.9367 μM	SANGER
NCI-H128	-	Growth Inhibition Assay	-	IC50=1.35814 μM	SANGER
NCI-H1299	-	Growth Inhibition Assay	-	IC50=38.1603 μM	SANGER
NCI-H1304	-	Growth Inhibition Assay	-	IC50=21.0311 μM	SANGER
NCI-H1355	-	Growth Inhibition Assay	-	IC50=0.68619 μM	SANGER
NCI-H1395	-	Growth Inhibition Assay	-	IC50=58.8172 μM	SANGER
NCI-H1417	-	Growth Inhibition Assay	-	IC50=180.331 μM	SANGER
NCI-H1436	-	Growth Inhibition Assay	-	IC50=72.7456 μM	SANGER
NCI-H1522	-	Growth Inhibition Assay	-	IC50=69.0047 μM	SANGER
NCI-H1581	-	Growth Inhibition Assay	-	IC50=6.23849 μM	SANGER
NCI-H1648	-	Growth Inhibition Assay	-	IC50=11.0965 μM	SANGER
NCI-H1650	-	Growth Inhibition Assay	-	IC50=4.15797 μM	SANGER
NCI-H1694	-	Growth Inhibition Assay	-	IC50=71.032 μM	SANGER
NCI-H1770	-	Growth Inhibition Assay	-	IC50=156.279 μM	SANGER
NCI-H1838	-	Growth Inhibition Assay	-	IC50=271.456 μM	SANGER
NCI-H187	-	Growth Inhibition Assay	-	IC50=190.064 μM	SANGER
NCI-H1882	-	Growth Inhibition Assay	-	IC50=0.59036 μM	SANGER
NCI-H1963	-	Growth Inhibition Assay	-	IC50=26.0623 μM	SANGER
NCI-H2081	-	Growth Inhibition Assay	-	IC50=1.55196 μM	SANGER
NCI-H209	-	Growth Inhibition Assay	-	IC50=5.19352 μM	SANGER
NCI-H2107	-	Growth Inhibition Assay	-	IC50=31.2338 μM	SANGER
NCI-H2126	-	Growth Inhibition Assay	-	IC50=0.62669 μM	SANGER
NCI-H2141	-	Growth Inhibition Assay	-	IC50=1.67317 μM	SANGER
NCI-H2171	-	Growth Inhibition Assay	-	IC50=79.4136 μM	SANGER
NCI-H2196	-	Growth Inhibition Assay	-	IC50=61.231 μM	SANGER
NCI-H2227	-	Growth Inhibition Assay	-	IC50=1.61561 μM	SANGER
NCI-H226	-	Growth Inhibition Assay	-	IC50=188.866 μM	SANGER
NCI-H23	-	Growth Inhibition Assay	-	IC50=1.2041 μM	SANGER
NCI-H322M	-	Growth Inhibition Assay	-	IC50=78.3709 μM	SANGER
NCI-H345	-	Growth Inhibition Assay	-	IC50=21.0643 μM	SANGER
NCI-H446	-	Growth Inhibition Assay	-	IC50=99.7588 μM	SANGER
NCI-H510A	-	Growth Inhibition Assay	-	IC50=127.32 μM	SANGER
NCI-H524	-	Growth Inhibition Assay	-	IC50=11.9822 μM	SANGER
NCI-H526	-	Growth Inhibition Assay	-	IC50=78.5877 μM	SANGER
NCI-H64	-	Growth Inhibition Assay	-	IC50=40.0948 μM	SANGER
NCI-H69	-	Growth Inhibition Assay	-	IC50=0.15141 μM	SANGER
NCI-H716	-	Growth Inhibition Assay	-	IC50=82.9075 μM	SANGER
NCI-H719	-	Growth Inhibition Assay	-	IC50=1.27411 μM	SANGER
NCI-H720	-	Growth Inhibition Assay	-	IC50=98.4061 μM	SANGER
NCI-H747	-	Growth Inhibition Assay	-	IC50=0.37103 μM	SANGER
NCI-H748	-	Growth Inhibition Assay	-	IC50=3.44266 μM	SANGER
NCI-H82	-	Growth Inhibition Assay	-	IC50=71.9507 μM	SANGER
NCI-H889	-	Growth Inhibition Assay	-	IC50=104.242 μM	SANGER
NCI-H929	1 μM	Cytotoxic Assay	72 h	IC50=0.17 μM	24625088
NCI-N87	-	Growth Inhibition Assay	-	IC50=13.736 μM	SANGER
NCI-SNU-1	-	Growth Inhibition Assay	-	IC50=10.4969 μM	SANGER
NCI-SNU-16	-	Growth Inhibition Assay	-	IC50=38.5653 μM	SANGER
NCI-SNU-5	-	Growth Inhibition Assay	-	IC50=0.69545 μM	SANGER
NEC8	-	Growth Inhibition Assay	-	IC50=0.11995 μM	SANGER
NH-12	-	Growth Inhibition Assay	-	IC50=10.2433 μM	SANGER
NKM-1	-	Growth Inhibition Assay	-	IC50=3.77378 μM	SANGER
NMC-G1	-	Growth Inhibition Assay	-	IC50=6.71895 μM	SANGER
no-10	-	Growth Inhibition Assay	-	IC50=0.08909 μM	SANGER
no-11	-	Growth Inhibition Assay	-	IC50=2.03104 μM	SANGER
NOMO-1	-	Growth Inhibition Assay	-	IC50=7.24254 μM	SANGER
NOS-1	-	Growth Inhibition Assay	-	IC50=12.0345 μM	SANGER
NTERA-S-cl-D1	-	Growth Inhibition Assay	-	IC50=0.05772 μM	SANGER
OCI-AML2	-	Growth Inhibition Assay	-	IC50=7.00326 μM	SANGER
OCI-Ly3	10 μM	Function Assay	4 h	Induces human IkappaBalpha stabilization with EC50 of 1 μM	18024113
OCUB-M	-	Growth Inhibition Assay	-	IC50=0.03737 μM	SANGER
OMC-1	-	Growth Inhibition Assay	-	IC50=8.52191 μM	SANGER
ONS-76	-	Growth Inhibition Assay	-	IC50=0.12935 μM	SANGER
OPM-2	-	Growth Inhibition Assay	-	IC50=0.10474 μM	SANGER
OS-RC-2	-	Growth Inhibition Assay	-	IC50=0.47972 μM	SANGER
OVCAR-4	-	Growth Inhibition Assay	-	IC50=0.10938 μM	SANGER
P30-OHK	-	Growth Inhibition Assay	-	IC50=283.847 μM	SANGER
P31-FUJ	-	Growth Inhibition Assay	-	IC50=20.4753 μM	SANGER
PC12	100 μM	Function Assay	24 h	Inhibits 6-OHDA- and H2O2-induced cytotoxicity	17158454
PC3	20 μM	Growth Inhibition Assay	48 h	IC50=0.6 μM	16686537
PF-382	-	Growth Inhibition Assay	-	IC50=0.16706 μM	SANGER
PSN1	-	Growth Inhibition Assay	-	IC50=1.27016 μM	SANGER
QIMR-WIL	-	Growth Inhibition Assay	-	IC50=2.16762 μM	SANGER
Raji	-	Growth Inhibition Assay	-	IC50=1.4185 μM	SANGER
Ramos-2G6-4C10	-	Growth Inhibition Assay	-	IC50=34.2993 μM	SANGER
RCC10RGB	-	Growth Inhibition Assay	-	IC50=38.2083 μM	SANGER
REH	-	Growth Inhibition Assay	-	IC50=236.626 μM	SANGER
RH-1	-	Growth Inhibition Assay	-	IC50=3.38748 μM	SANGER
RKO	-	Growth Inhibition Assay	-	IC50=5.23422 μM	SANGER
RL	-	Growth Inhibition Assay	-	IC50=5.37541 μM	SANGER
RL95-2	-	Growth Inhibition Assay	-	IC50=8.10842 μM	SANGER
RPMI-6666	-	Growth Inhibition Assay	-	IC50=21.3602 μM	SANGER
RPMI-8226	-	Growth Inhibition Assay	-	IC50=84.2107 μM	SANGER
RPMI-8402	-	Growth Inhibition Assay	-	IC50=58.9526 μM	SANGER
RPMI-8866	-	Growth Inhibition Assay	-	IC50=74.7509 μM	SANGER
RS4-11	-	Growth Inhibition Assay	-	IC50=82.2505 μM	SANGER
RXF393	-	Growth Inhibition Assay	-	IC50=0.25015 μM	SANGER
SBC-1	-	Growth Inhibition Assay	-	IC50=42.1806 μM	SANGER
SCC-15	-	Growth Inhibition Assay	-	IC50=72.34 μM	SANGER
SCC-3	-	Growth Inhibition Assay	-	IC50=3.10848 μM	SANGER
SCH	-	Growth Inhibition Assay	-	IC50=60.9638 μM	SANGER
SCLC-21H	-	Growth Inhibition Assay	-	IC50=10.6596 μM	SANGER
SF126	-	Growth Inhibition Assay	-	IC50=0.98971 μM	SANGER
SF268	-	Growth Inhibition Assay	-	IC50=0.65641 μM	SANGER
SF539	-	Growth Inhibition Assay	-	IC50=192.728 μM	SANGER
SH-4	-	Growth Inhibition Assay	-	IC50=0.0431 μM	SANGER
SHP-77	-	Growth Inhibition Assay	-	IC50=7.2243 μM	SANGER
SIG-M5	-	Growth Inhibition Assay	-	IC50=30.7952 μM	SANGER
SIMA	-	Growth Inhibition Assay	-	IC50=5.30765 μM	SANGER
SJSA-1	-	Growth Inhibition Assay	-	IC50=9.09091 μM	SANGER
SK-LMS-1	-	Growth Inhibition Assay	-	IC50=0.19303 μM	SANGER
SKM-1	-	Growth Inhibition Assay	-	IC50=3.71376 μM	SANGER
SK-MEL-1	-	Growth Inhibition Assay	-	IC50=118.009 μM	SANGER
SK-MEL-2	-	Growth Inhibition Assay	-	IC50=63.9892 μM	SANGER
SK-MM-2	-	Growth Inhibition Assay	-	IC50=11.8061 μM	SANGER
SK-N-DZ	-	Growth Inhibition Assay	-	IC50=7.71089 μM	SANGER
SK-NEP-1	-	Growth Inhibition Assay	-	IC50=75.0754 μM	SANGER
SK-N-FI	-	Growth Inhibition Assay	-	IC50=6.45854 μM	SANGER
SK-PN-DW	-	Growth Inhibition Assay	-	IC50=0.2319 μM	SANGER
SK-UT-1	-	Growth Inhibition Assay	-	IC50=0.22049 μM	SANGER
SMMC-7721	40 μM	Cytotoxic Assay	48 h	IC50=7.1 μM	24697496
SNB75	-	Growth Inhibition Assay	-	IC50=3.60103 μM	SANGER
SNU-C1	-	Growth Inhibition Assay	-	IC50=31.3126 μM	SANGER
SNU-C2B	-	Growth Inhibition Assay	-	IC50=0.70739 μM	SANGER
SR	-	Growth Inhibition Assay	-	IC50=11.0185 μM	SANGER
ST486	-	Growth Inhibition Assay	-	IC50=25.1113 μM	SANGER
SU-DHL-1	-	Growth Inhibition Assay	-	IC50=1.71281 μM	SANGER
SUP-T1	-	Growth Inhibition Assay	-	IC50=143.708 μM	SANGER
SW-480	40 μM	Cytotoxic Assay	48 h	IC50=4 μM	24697496
SW684	-	Growth Inhibition Assay	-	IC50=1.28659 μM	SANGER
SW872	-	Growth Inhibition Assay	-	IC50=0.65729 μM	SANGER
SW954	-	Growth Inhibition Assay	-	IC50=47.4128 μM	SANGER
SW962	-	Growth Inhibition Assay	-	IC50=54.8357 μM	SANGER
SW982	-	Growth Inhibition Assay	-	IC50=2.5148 μM	SANGER
TALL-1	-	Growth Inhibition Assay	-	IC50=198.304 μM	SANGER
TC-YIK	-	Growth Inhibition Assay	-	IC50=50.0363 μM	SANGER
TE-1	-	Growth Inhibition Assay	-	IC50=0.45119 μM	SANGER
TE-10	-	Growth Inhibition Assay	-	IC50=0.9643 μM	SANGER
TE-11	-	Growth Inhibition Assay	-	IC50=34.4822 μM	SANGER
TE-12	-	Growth Inhibition Assay	-	IC50=13.6994 μM	SANGER
TE-15	-	Growth Inhibition Assay	-	IC50=1.92373 μM	SANGER
TE-441-T	-	Growth Inhibition Assay	-	IC50=199.739 μM	SANGER
TE-5	-	Growth Inhibition Assay	-	IC50=0.14278 μM	SANGER
TE-6	-	Growth Inhibition Assay	-	IC50=3.94561 μM	SANGER
TE-8	-	Growth Inhibition Assay	-	IC50=0.34279 μM	SANGER
TE-9	-	Growth Inhibition Assay	-	IC50=0.61033 μM	SANGER
TGBC1TKB	-	Growth Inhibition Assay	-	IC50=11.4102 μM	SANGER
TGBC24TKB	-	Growth Inhibition Assay	-	IC50=62.1491 μM	SANGER
TGW	-	Growth Inhibition Assay	-	IC50=6.45593 μM	SANGER
THP-1	-	Growth Inhibition Assay	-	IC50=264.738 μM	SANGER
TK10	-	Growth Inhibition Assay	-	IC50=0.25435 μM	SANGER
TUR	-	Growth Inhibition Assay	-	IC50=167.87 μM	SANGER
U-266	-	Growth Inhibition Assay	-	IC50=6.51926 μM	SANGER
U-698-M	-	Growth Inhibition Assay	-	IC50=68.5687 μM	SANGER
U-87-MG	-	Growth Inhibition Assay	-	IC50=26.7644 μM	SANGER
UACC-257	-	Growth Inhibition Assay	-	IC50=0.11927 μM	SANGER
UACC-812	-	Growth Inhibition Assay	-	IC50=69.5209 μM	SANGER
VA-ES-BJ	-	Growth Inhibition Assay	-	IC50=0.22257 μM	SANGER
WSU-NHL	-	Growth Inhibition Assay	-	IC50=109.671 μM	SANGER
YT	-	Growth Inhibition Assay	-	IC50=4.35424 μM	SANGER

MG-132 Catalog No. CSN11436

靶点选择性

请登录您的专属账户

确认信息