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CAS No.: 50656-77-4

Niranthin Catalog No. CSN14342

Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites.

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400-920-2911

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技术信息

生物活性

描述Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites. Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme.
参考文献

[1] Liu S, Wei W, et al. In vitro and in vivo anti-hepatitis B virus activities of the lignan niranthin isolated from Phyllanthus niruri L. J Ethnopharmacol. 2014 Sep 11;155(2):1061-7.
[2] Chowdhury S, Mukherjee T, et al. The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice. EMBO Mol Med. 2012 Oct;4(10):1126-43.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.3121 mL
- 11.5605 mL
- 23.1210 mL
- 5 mM
- 0.4624 mL
- 2.3121 mL
- 4.6242 mL
- 10 mM
- 0.2312 mL
- 1.1561 mL
- 2.3121 mL

技术信息

CAS号	50656-77-4	储存条件	粉末液体 -20°C:3-6 月 -80°C:12月
分子式	C24H32O7	运输	蓝冰
分子量	432.51	别名

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