CAS No.: 177707-12-9
NKP608 Catalog No. CSN18026
Synonyms: AV-608;CGP-608
NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro (IC50=2.6 nM) and in vivo.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] El-Hashim AZ, Wyss D, et al. Effect of a novel NK1 receptor selective antagonist (NKP608) on citric acid induced cough and airway obstruction. Pulm Pharmacol Ther. 2004;17(1):11-8.
- [2] Vendruscolo LF, Takahashi RN, et al. Evaluation of the anxiolytic-like effect of NKP608, a NK1-receptor antagonist, in two rat strains that differ in anxiety-related behaviors. Psychopharmacology (Berl). 2003 Nov;170(3):287-93.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 177707-12-9 | 储存条件 |
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| 分子式 | C31H24ClF6N3O2 | 运输 | 蓝冰 | |
| 分子量 | 619.98 | 别名 | AV-608;CGP-608 |
