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CAS No.: 204326-43-2
NS-2028 is a potent soluble guanylyl cyclase (sGC) inhibitor with Ki of 8 nM. NS-2028 inhibits sGC activity in homogenates of mouse cerebellum and neuronal NO synthase with IC50 values of 17 nM and 20 nM[1]. NS-2028 is commonly used in the research of nitric oxide signaling pathways, it inhibits NO-dependent relaxant responses in non-vascular smooth muscle completely (1 μM)[1]. NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability[2].
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实验方案
技术信息
CAS号 | 204326-43-2 | 储存条件 |
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分子式 | C9H5BrN2O3 | 运输 | 蓝冰 | |
分子量 | 269.05 | 别名 |
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