CAS No.: 204697-65-4
Olcegepant Catalog No. CSN18095
Synonyms: BIBN-4096;OlcegepantOlcegepant;BIBN 4096BS
Olcegepant is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor (IC50= 0.03 nM).
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
|---|
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Rudolf K, Eberlein W, et al. Development of human calcitonin gene-related peptide (CGRP) receptor antagonists. 1. Potent and selective small molecule CGRP antagonists. 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl] carbonyl] -D-tyrosyl] -l-lysyl] -4-(4-pyridinyl)piperazine: the first CGRP antagonist for clinical trials in acute migraine. J Med Chem. 2005 Sep 22;48(19):5921-31.
- [2] Doods H, Hallermayer G, et al. Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist. Br J Pharmacol. 2000 Feb;129(3):420-3.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 204697-65-4 | 储存条件 |
|
|
| 分子式 | C38H47Br2N9O5 | 运输 | 蓝冰 | |
| 分子量 | 869.65 | 别名 | BIBN-4096;OlcegepantOlcegepant;BIBN 4096BS |
