|氧化槐定碱|CsnPharm

CAS No.: 54809-74-4

Oxysophoridine/氧化槐定碱 Catalog No. CSN11639

Synonyms: Sophoridine N-oxide;氧化槐定碱

Oxysophoridine is a natural product isolated and purified from the herb of Sophora alopecuroidos L. Oxysophoridine inhibited N-methyl-D-aspartate NR1 mRNA and protein expression in the cerebral cortex of mice with cerebral ischemia/reperfusion injury.

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技术信息

生物活性

描述Oxysophoridine is a natural product isolated and purified from the herb of Sophora alopecuroidos L. with a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms. Oxysophoridine ameliorates cardiac damage in a rat model of AMI and that this cardioprotection may be linked with its anti-oxidative, anti-apoptotic and anti-inflammatory properties. Oxysophoridine may be a potential neuroprotective agent for cerebral ischemia injury, that the effect may be due to its ability to inhibit oxidative stress and expression of the N-methyl-D-aspartate receptor subunit NR1.
参考文献

[1] Fu J, Wang Y, et al. Anti-inflammatory and anti-apoptotic effects of oxysophoridine on lipopolysaccharide-induced acute lung injury in mice. Am J Transl Res. 2015 Dec 15;7(12):2672-82.
[2] Rui C, Yuxiang L, et al. Anti-apoptotic and neuroprotective effects of oxysophoridine on cerebral ischemia both in vivo and in vitro. Planta Med. 2013 Jul;79(11):916-23.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.7827 mL
- 18.9134 mL
- 37.8267 mL
- 5 mM
- 0.7565 mL
- 3.7827 mL
- 7.5653 mL
- 10 mM
- 0.3783 mL
- 1.8913 mL
- 3.7827 mL

技术信息

CAS号	54809-74-4	储存条件	粉末 Sealed in dry,Store in freezer, under -20°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C15H24N2O2	运输	蓝冰
分子量	264.36	别名	Sophoridine N-oxide;氧化槐定碱

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