|N-[2-[4-(二乙氨基)丁基]氨基-6-(3,5-二甲氧基苯基)吡啶并[2,3-D-7-嘧啶基]-N'-(1,1-二甲基)脲|CsnPharm

CAS No.: 219580-11-7

PD173074 Catalog No. CSN12916

Synonyms: PD173074

PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM, ~1000-fold selective for FGFR1 than PDGFR and c-Src.

规格	价格	促销价格	库存	数量

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纯度 & 质量文件批次:

靶点选择性

生物活性

实验方案

技术信息

生物活性

靶点 FGFR1

IC50:~25nM VEGFR2

IC50:100nM-200nM
描述Angiogenesis, playing a major role in the progression of human diseases such as diabetic retinopathy, atherosclerosis and cancer, involves the concerted action of a number of polypeptide factors such as VEGF, Ang1 and FGF. PD173074 is a selective dual inhibitor of both FGFR1 and VEGFR2 with IC50 value of 21.5nM (measured by kinase activity) and 100-200nM (measured by VEGFR2 auto-phosphorylation in NIH 3T3 cells), respectively. PD173074 inhibited auto-phosphorylation of FGFR1, induced by aFGF and heparin, of NIH-3T3 cells expressing FGFR1 endogenously in a dose-dependent manner with an IC50 in the range 1–5nM, as well as auto-phosphorylation of overexpressed VEGFR2 stimulated with VEGF (100ng/ml) with an IC50 of 100–200nM. Mice treated daily with PD173074 by intraperitoneal injection per day starting 3 days prior to pellet implantation exhibited inhibition of bFGF-induced neovascularization by 86% at a dose of 1mg/kg, as well as inhibition of VEGF induced neovascularization by 81% at a dose of 2mg/kg^[1]. PD173704 can specifically and effectively inhibit multiple FGF-2-mediated responses of both oligodendrocyte progenitors, as well as differentiated oligodendrocytes with complete antagonization on two phenotypic alterations, downregulation of myelin proteins, and their re-entry into the cell cycle^[2].
作用机制PD173074 is an ATP-competitive inhibitor of FGFR1.^[1]
细胞研究

Cell Data

Cell Lines	Concentration	Assay Type	Time	Activity Description	Data Sources
A204	-	Growth Inhibition Assay	-	IC50=3.92075 μM	SANGER
A2058	-	Growth Inhibition Assay	-	IC50=35.6061 μM	SANGER
A253	-	Growth Inhibition Assay	-	IC50=15.3869 μM	SANGER

更多
动物研究
剂量
Nude Mice^[3]: 12 mg/kg Mice: 1 mg/kg, 2 mg/kg^[1] (i.p.), 25 mg/kg - 100 mg/kg^[4] (p.o.)

给药途径
i.p., p.o.

动物研究
剂量	Nude Mice^[3]: 12 mg/kg Mice: 1 mg/kg, 2 mg/kg^[1] (i.p.), 25 mg/kg - 100 mg/kg^[4] (p.o.)
给药途径	i.p., p.o.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.9096 mL
- 9.5480 mL
- 19.0960 mL
- 5 mM
- 0.3819 mL
- 1.9096 mL
- 3.8192 mL
- 10 mM
- 0.1910 mL
- 0.9548 mL
- 1.9096 mL

技术信息

CAS号

219580-11-7

储存条件

粉末: Keep in dark place,Inert atmosphere,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C28H41N7O3

运输

蓝冰

分子量

523.67

别名

PD173074

溶解度

DMSO	100.0 mg/mL (191.0 mM) warming
Water	insoluble

动物实验配方

IP	2% DMSO+2% Tween80+40% PEG300+water	2 mg/mL	clear
PO	0.5% CMC-Na	35 mg/mL	suspension

大规格询价

号为必填项

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Cell Lines	Concentration	Assay Type	Time	Activity Description	Data Sources

A204	-	Growth Inhibition Assay	-	IC50=3.92075 μM	SANGER
A2058	-	Growth Inhibition Assay	-	IC50=35.6061 μM	SANGER
A253	-	Growth Inhibition Assay	-	IC50=15.3869 μM	SANGER
A2780	-	Growth Inhibition Assay	-	IC50=11.0308 μM	SANGER
A3-KAW	-	Growth Inhibition Assay	-	IC50=31.9243 μM	SANGER
A427	-	Growth Inhibition Assay	-	IC50=25.0323 μM	SANGER
A4-Fuk	-	Growth Inhibition Assay	-	IC50=6.73142 μM	SANGER
A704	-	Growth Inhibition Assay	-	IC50=4.28723 μM	SANGER
AN3-CA	-	Growth Inhibition Assay	-	IC50=0.40133 μM	SANGER
BE-13	-	Growth Inhibition Assay	-	IC50=10.6576 μM	SANGER
BHT-101	-	Growth Inhibition Assay	-	IC50=11.4456 μM	SANGER
BV-173	-	Growth Inhibition Assay	-	IC50=0.84623 μM	SANGER
C8166	-	Growth Inhibition Assay	-	IC50=33.3192 μM	SANGER
Ca9-22	-	Growth Inhibition Assay	-	IC50=29.4557 μM	SANGER
CAKI-1	-	Growth Inhibition Assay	-	IC50=12.791 μM	SANGER
CAL-120	-	Growth Inhibition Assay	-	IC50=16.9879 μM	SANGER
CAL-33	-	Growth Inhibition Assay	-	IC50=45.9217 μM	SANGER
CAL-72	-	Growth Inhibition Assay	-	IC50=4.41746 μM	SANGER
CAPAN-1	-	Growth Inhibition Assay	-	IC50=36.4699 μM	SANGER
CAS-1	-	Growth Inhibition Assay	-	IC50=9.97659 μM	SANGER
CCRF-CEM	-	Growth Inhibition Assay	-	IC50=3.50488 μM	SANGER
CHL-1	-	Growth Inhibition Assay	-	IC50=3.65799 μM	SANGER
CHP-134	-	Growth Inhibition Assay	-	IC50=6.25182 μM	SANGER
COLO-320-HSR	-	Growth Inhibition Assay	-	IC50=44.5633 μM	SANGER
COLO-684	-	Growth Inhibition Assay	-	IC50=13.5318 μM	SANGER
COLO-800	-	Growth Inhibition Assay	-	IC50=25.1061 μM	SANGER
COR-L88	-	Growth Inhibition Assay	-	IC50=8.50981 μM	SANGER
CTB-1	-	Growth Inhibition Assay	-	IC50=3.80051 μM	SANGER
CTV-1	-	Growth Inhibition Assay	-	IC50=21.6172 μM	SANGER
D-263MG	-	Growth Inhibition Assay	-	IC50=0.71159 μM	SANGER
D-283MED	-	Growth Inhibition Assay	-	IC50=9.06534 μM	SANGER
D-336MG	-	Growth Inhibition Assay	-	IC50=4.46817 μM	SANGER
D-423MG	-	Growth Inhibition Assay	-	IC50=19.3952 μM	SANGER
D-502MG	-	Growth Inhibition Assay	-	IC50=28.4 μM	SANGER
D-566MG	-	Growth Inhibition Assay	-	IC50=22.7601 μM	SANGER
DB	-	Growth Inhibition Assay	-	IC50=8.11504 μM	SANGER
DBTRG-05MG	-	Growth Inhibition Assay	-	IC50=9.09607 μM	SANGER
DEL	-	Growth Inhibition Assay	-	IC50=20.9808 μM	SANGER
DJM-1	-	Growth Inhibition Assay	-	IC50=40.9799 μM	SANGER
DMS-114	-	Growth Inhibition Assay	-	IC50=1.36737 μM	SANGER
DOHH-2	-	Growth Inhibition Assay	-	IC50=38.7158 μM	SANGER
DU-145	-	Growth Inhibition Assay	-	IC50=1.58217 μM	SANGER
DU-4475	-	Growth Inhibition Assay	-	IC50=19.8852 μM	SANGER
ECC10	-	Growth Inhibition Assay	-	IC50=0.33898 μM	SANGER
EFM-19	-	Growth Inhibition Assay	-	IC50=26.8145 μM	SANGER
EFO-27	-	Growth Inhibition Assay	-	IC50=23.0651 μM	SANGER
EM-2	-	Growth Inhibition Assay	-	IC50=10.1393 μM	SANGER
EoL-1-cell	-	Growth Inhibition Assay	-	IC50=0.32984 μM	SANGER
ES1	-	Growth Inhibition Assay	-	IC50=39.385 μM	SANGER
ES4	-	Growth Inhibition Assay	-	IC50=9.50595 μM	SANGER
ES5	-	Growth Inhibition Assay	-	IC50=3.83637 μM	SANGER
ES8	-	Growth Inhibition Assay	-	IC50=7.69626 μM	SANGER
ESS-1	-	Growth Inhibition Assay	-	IC50=30.4759 μM	SANGER
EW-13	-	Growth Inhibition Assay	-	IC50=9.89055 μM	SANGER
EW-16	-	Growth Inhibition Assay	-	IC50=13.3187 μM	SANGER
EW-18	-	Growth Inhibition Assay	-	IC50=28.4386 μM	SANGER
EW-3	-	Growth Inhibition Assay	-	IC50=3.98923 μM	SANGER
FTC-133	-	Growth Inhibition Assay	-	IC50=25.8186 μM	SANGER
G-401	-	Growth Inhibition Assay	-	IC50=2.47189 μM	SANGER
G-402	-	Growth Inhibition Assay	-	IC50=3.12727 μM	SANGER
GAMG	-	Growth Inhibition Assay	-	IC50=3.46576 μM	SANGER
GI-ME-N	-	Growth Inhibition Assay	-	IC50=4.5481 μM	SANGER
GOTO	-	Growth Inhibition Assay	-	IC50=11.2084 μM	SANGER
GR-ST	-	Growth Inhibition Assay	-	IC50=12.5295 μM	SANGER
GT3TKB	-	Growth Inhibition Assay	-	IC50=43.2679 μM	SANGER
H4	-	Growth Inhibition Assay	-	IC50=16.088 μM	SANGER
H9	-	Growth Inhibition Assay	-	IC50=2.14306 μM	SANGER
HAL-01	-	Growth Inhibition Assay	-	IC50=7.48341 μM	SANGER
HCC1187	-	Growth Inhibition Assay	-	IC50=46.4255 μM	SANGER
HCC1395	-	Growth Inhibition Assay	-	IC50=18.4301 μM	SANGER
HCC1569	-	Growth Inhibition Assay	-	IC50=20.2624 μM	SANGER
HCC2157	-	Growth Inhibition Assay	-	IC50=29.8807 μM	SANGER
HCC2218	-	Growth Inhibition Assay	-	IC50=2.37939 μM	SANGER
HCC2998	-	Growth Inhibition Assay	-	IC50=35.1529 μM	SANGER
HCT-116	-	Growth Inhibition Assay	-	IC50=44.9868 μM	SANGER
HDLM-2	-	Growth Inhibition Assay	-	IC50=15.1286 μM	SANGER
H-EMC-SS	-	Growth Inhibition Assay	-	IC50=0.34715 μM	SANGER
HGC-27	-	Growth Inhibition Assay	-	IC50=38.3711 μM	SANGER
HH	-	Growth Inhibition Assay	-	IC50=3.47676 μM	SANGER
HL-60	-	Growth Inhibition Assay	-	IC50=40.9783 μM	SANGER
HOP-92	-	Growth Inhibition Assay	-	IC50=31.1111 μM	SANGER
HOS	-	Growth Inhibition Assay	-	IC50=9.35134 μM	SANGER
Hs-578-T	-	Growth Inhibition Assay	-	IC50=3.67873 μM	SANGER
HuH-7	-	Growth Inhibition Assay	-	IC50=1.24464 μM	SANGER
HuO-3N1	-	Growth Inhibition Assay	-	IC50=0.54653 μM	SANGER
HuO9	-	Growth Inhibition Assay	-	IC50=5.38843 μM	SANGER
IA-LM	-	Growth Inhibition Assay	-	IC50=33.275 μM	SANGER
IGROV-1	-	Growth Inhibition Assay	-	IC50=4.87168 μM	SANGER
IST-MES1	-	Growth Inhibition Assay	-	IC50=9.94534 μM	SANGER
J82	-	Growth Inhibition Assay	-	IC50=31.0897 μM	SANGER
JEG-3	-	Growth Inhibition Assay	-	IC50=33.4768 μM	SANGER
J-RT3-T3-5	-	Growth Inhibition Assay	-	IC50=7.07764 μM	SANGER
JVM-2	-	Growth Inhibition Assay	-	IC50=32.9079 μM	SANGER
JVM-3	-	Growth Inhibition Assay	-	IC50=44.0533 μM	SANGER
K5	-	Growth Inhibition Assay	-	IC50=30.764 μM	SANGER
K-562	-	Growth Inhibition Assay	-	IC50=30.0933 μM	SANGER
KARPAS-299	-	Growth Inhibition Assay	-	IC50=21.529 μM	SANGER
KARPAS-45	-	Growth Inhibition Assay	-	IC50=2.70747 μM	SANGER
KE-37	-	Growth Inhibition Assay	-	IC50=38.9828 μM	SANGER
KG-1	-	Growth Inhibition Assay	-	IC50=0.05129 μM	SANGER
KM-H2	-	Growth Inhibition Assay	-	IC50=4.55222 μM	SANGER
KP-N-YN	-	Growth Inhibition Assay	-	IC50=48.2102 μM	SANGER
KS-1	-	Growth Inhibition Assay	-	IC50=24.2759 μM	SANGER
KU812	-	Growth Inhibition Assay	-	IC50=10.7391 μM	SANGER
KY821	-	Growth Inhibition Assay	-	IC50=32.6884 μM	SANGER
KYSE-510	-	Growth Inhibition Assay	-	IC50=40.1295 μM	SANGER
KYSE-520	-	Growth Inhibition Assay	-	IC50=34.7181 μM	SANGER
KYSE-70	-	Growth Inhibition Assay	-	IC50=29.5786 μM	SANGER
L-363	-	Growth Inhibition Assay	-	IC50=4.96665 μM	SANGER
LAMA-84	-	Growth Inhibition Assay	-	IC50=4.5331 μM	SANGER
LB1047-RCC	-	Growth Inhibition Assay	-	IC50=8.52212 μM	SANGER
LB2241-RCC	-	Growth Inhibition Assay	-	IC50=47.727 μM	SANGER
LC-2-ad	-	Growth Inhibition Assay	-	IC50=19.7612 μM	SANGER
LCLC-103H	-	Growth Inhibition Assay	-	IC50=32.0171 μM	SANGER
LCLC-97TM1	-	Growth Inhibition Assay	-	IC50=16.5889 μM	SANGER
LK-2	-	Growth Inhibition Assay	-	IC50=3.67133 μM	SANGER
LU-134-A	-	Growth Inhibition Assay	-	IC50=17.3391 μM	SANGER
LU-135	-	Growth Inhibition Assay	-	IC50=42.5447 μM	SANGER
LU-139	-	Growth Inhibition Assay	-	IC50=4.31534 μM	SANGER
LU-65	-	Growth Inhibition Assay	-	IC50=16.3384 μM	SANGER
LXF-289	-	Growth Inhibition Assay	-	IC50=13.0835 μM	SANGER
MC116	-	Growth Inhibition Assay	-	IC50=17.975 μM	SANGER
MCF7	-	Growth Inhibition Assay	-	IC50=11.6167 μM	SANGER
MDA-MB-231	-	Growth Inhibition Assay	-	IC50=43.9609 μM	SANGER
MDA-MB-453	-	Growth Inhibition Assay	-	IC50=34.6395 μM	SANGER
ME-180	-	Growth Inhibition Assay	-	IC50=7.10404 μM	SANGER
MEG-01	-	Growth Inhibition Assay	-	IC50=15.9107 μM	SANGER
MEL-HO	-	Growth Inhibition Assay	-	IC50=25.4319 μM	SANGER
MFE-280	-	Growth Inhibition Assay	-	IC50=0.85872 μM	SANGER
MFM-223	-	Growth Inhibition Assay	-	IC50=0.21576 μM	SANGER
MG-63	-	Growth Inhibition Assay	-	IC50=2.94262 μM	SANGER
MHH-ES-1	-	Growth Inhibition Assay	-	IC50=21.3597 μM	SANGER
MHH-PREB-1	-	Growth Inhibition Assay	-	IC50=13.2704 μM	SANGER
MKN45	-	Growth Inhibition Assay	-	IC50=11.7993 μM	SANGER
MKN7	-	Growth Inhibition Assay	-	IC50=14.6676 μM	SANGER
ML-2	-	Growth Inhibition Assay	-	IC50=6.24977 μM	SANGER
MMAC-SF	-	Growth Inhibition Assay	-	IC50=13.4547 μM	SANGER
MOLT-13	-	Growth Inhibition Assay	-	IC50=39.2502 μM	SANGER
MOLT-16	-	Growth Inhibition Assay	-	IC50=11.9692 μM	SANGER
MOLT-4	-	Growth Inhibition Assay	-	IC50=36.2294 μM	SANGER
Mo-T	-	Growth Inhibition Assay	-	IC50=33.1005 μM	SANGER
MPP-89	-	Growth Inhibition Assay	-	IC50=2.48364 μM	SANGER
MS-1	-	Growth Inhibition Assay	-	IC50=33.5551 μM	SANGER
MSTO-211H	-	Growth Inhibition Assay	-	IC50=1.47378 μM	SANGER
MV-4-11	-	Growth Inhibition Assay	-	IC50=6.76626 μM	SANGER
NB10	-	Growth Inhibition Assay	-	IC50=28.2297 μM	SANGER
NB69	-	Growth Inhibition Assay	-	IC50=13.9868 μM	SANGER
NBsusSR	-	Growth Inhibition Assay	-	IC50=3.63969 μM	SANGER
NCI-H1048	-	Growth Inhibition Assay	-	IC50=16.5165 μM	SANGER
NCI-H1092	-	Growth Inhibition Assay	-	IC50=3.1969 μM	SANGER
NCI-H1155	-	Growth Inhibition Assay	-	IC50=11.4947 μM	SANGER
NCI-H1304	-	Growth Inhibition Assay	-	IC50=33.5725 μM	SANGER
NCI-H1355	-	Growth Inhibition Assay	-	IC50=6.41733 μM	SANGER
NCI-H1437	-	Growth Inhibition Assay	-	IC50=46.321 μM	SANGER
NCI-H1581	-	Growth Inhibition Assay	-	IC50=0.01225 μM	SANGER
NCI-H1755	-	Growth Inhibition Assay	-	IC50=48.2726 μM	SANGER
NCI-H1770	-	Growth Inhibition Assay	-	IC50=5.95032 μM	SANGER
NCI-H2030	-	Growth Inhibition Assay	-	IC50=42.4368 μM	SANGER
NCI-H209	-	Growth Inhibition Assay	-	IC50=4.58283 μM	SANGER
NCI-H2228	-	Growth Inhibition Assay	-	IC50=31.3296 μM	SANGER
NCI-H226	-	Growth Inhibition Assay	-	IC50=45.6368 μM	SANGER
NCI-H2291	-	Growth Inhibition Assay	-	IC50=14.4453 μM	SANGER
NCI-H2452	-	Growth Inhibition Assay	-	IC50=22.6677 μM	SANGER
NCI-H358	-	Growth Inhibition Assay	-	IC50=48.1152 μM	SANGER
NCI-H441	-	Growth Inhibition Assay	-	IC50=44.9328 μM	SANGER
NCI-H446	-	Growth Inhibition Assay	-	IC50=9.29526 μM	SANGER
NCI-H520	-	Growth Inhibition Assay	-	IC50=8.62157 μM	SANGER
NCI-H526	-	Growth Inhibition Assay	-	IC50=11.3837 μM	SANGER
NCI-H596	-	Growth Inhibition Assay	-	IC50=23.8527 μM	SANGER
NCI-H69	-	Growth Inhibition Assay	-	IC50=17.9307 μM	SANGER
NCI-H720	-	Growth Inhibition Assay	-	IC50=2.21283 μM	SANGER
NCI-H82	-	Growth Inhibition Assay	-	IC50=13.4195 μM	SANGER
NCI-N87	-	Growth Inhibition Assay	-	IC50=48.2991 μM	SANGER
NCI-SNU-1	-	Growth Inhibition Assay	-	IC50=2.18394 μM	SANGER
NCI-SNU-5	-	Growth Inhibition Assay	-	IC50=31.8137 μM	SANGER
NEC8	-	Growth Inhibition Assay	-	IC50=0.56289 μM	SANGER
NKM-1	-	Growth Inhibition Assay	-	IC50=3.13564 μM	SANGER
no-10	-	Growth Inhibition Assay	-	IC50=18.6388 μM	SANGER
NOS-1	-	Growth Inhibition Assay	-	IC50=5.72927 μM	SANGER
NTERA-S-cl-D1	-	Growth Inhibition Assay	-	IC50=3.03472 μM	SANGER
NUGC-3	-	Growth Inhibition Assay	-	IC50=46.5709 μM	SANGER
NY	-	Growth Inhibition Assay	-	IC50=19.0809 μM	SANGER
OAW-42	-	Growth Inhibition Assay	-	IC50=10.5267 μM	SANGER
OCI-AML2	-	Growth Inhibition Assay	-	IC50=31.361 μM	SANGER
OS-RC-2	-	Growth Inhibition Assay	-	IC50=19.1252 μM	SANGER
OVCAR-3	-	Growth Inhibition Assay	-	IC50=36.2045 μM	SANGER
OVCAR-8	-	Growth Inhibition Assay	-	IC50=47.683 μM	SANGER
P12-ICHIKAWA	-	Growth Inhibition Assay	-	IC50=12.3845 μM	SANGER
PANC-08-13	-	Growth Inhibition Assay	-	IC50=48.1853 μM	SANGER
QIMR-WIL	-	Growth Inhibition Assay	-	IC50=13.8109 μM	SANGER
Ramos-2G6-4C10	-	Growth Inhibition Assay	-	IC50=34.0335 μM	SANGER
RH-18	-	Growth Inhibition Assay	-	IC50=3.19598 μM	SANGER
RO82-W-1	-	Growth Inhibition Assay	-	IC50=3.49855 μM	SANGER
RPMI-2650	-	Growth Inhibition Assay	-	IC50=43.7816 μM	SANGER
RPMI-8226	-	Growth Inhibition Assay	-	IC50=3.23447 μM	SANGER
RS4-11	-	Growth Inhibition Assay	-	IC50=1.33886 μM	SANGER
RT-112	-	Growth Inhibition Assay	-	IC50=0.54701 μM	SANGER
SAS	-	Growth Inhibition Assay	-	IC50=43.9534 μM	SANGER
SBC-1	-	Growth Inhibition Assay	-	IC50=2.094 μM	SANGER
SCC-9	-	Growth Inhibition Assay	-	IC50=37.4027 μM	SANGER
SF126	-	Growth Inhibition Assay	-	IC50=6.21406 μM	SANGER
SF268	-	Growth Inhibition Assay	-	IC50=38.3433 μM	SANGER
SF295	-	Growth Inhibition Assay	-	IC50=26.296 μM	SANGER
SJRH30	-	Growth Inhibition Assay	-	IC50=25.3908 μM	SANGER
SK-LU-1	-	Growth Inhibition Assay	-	IC50=15.9094 μM	SANGER
SK-MEL-1	-	Growth Inhibition Assay	-	IC50=17.7127 μM	SANGER
SK-MEL-28	-	Growth Inhibition Assay	-	IC50=7.37819 μM	SANGER
SK-MEL-3	-	Growth Inhibition Assay	-	IC50=5.2406 μM	SANGER
SK-MEL-30	-	Growth Inhibition Assay	-	IC50=10.8901 μM	SANGER
SK-N-DZ	-	Growth Inhibition Assay	-	IC50=15.9376 μM	SANGER
SK-NEP-1	-	Growth Inhibition Assay	-	IC50=8.48149 μM	SANGER
SK-OV-3	-	Growth Inhibition Assay	-	IC50=39.9643 μM	SANGER
SK-UT-1	-	Growth Inhibition Assay	-	IC50=6.91784 μM	SANGER
SN12C	-	Growth Inhibition Assay	-	IC50=30.1426 μM	SANGER
SNB75	-	Growth Inhibition Assay	-	IC50=44.6105 μM	SANGER
SNU-449	-	Growth Inhibition Assay	-	IC50=40.0764 μM	SANGER
SW1710	-	Growth Inhibition Assay	-	IC50=26.4123 μM	SANGER
SW780	-	Growth Inhibition Assay	-	IC50=3.92245 μM	SANGER
SW900	-	Growth Inhibition Assay	-	IC50=34.8115 μM	SANGER
SW948	-	Growth Inhibition Assay	-	IC50=10.1882 μM	SANGER
SW954	-	Growth Inhibition Assay	-	IC50=8.69786 μM	SANGER
SW962	-	Growth Inhibition Assay	-	IC50=0.78988 μM	SANGER
T98G	-	Growth Inhibition Assay	-	IC50=47.547 μM	SANGER
TCCSUP	-	Growth Inhibition Assay	-	IC50=33.4307 μM	SANGER
TE-12	-	Growth Inhibition Assay	-	IC50=6.72671 μM	SANGER
TE-6	-	Growth Inhibition Assay	-	IC50=8.75143 μM	SANGER
TE-9	-	Growth Inhibition Assay	-	IC50=29.8865 μM	SANGER
TGBC11TKB	-	Growth Inhibition Assay	-	IC50=41.0926 μM	SANGER
TGBC24TKB	-	Growth Inhibition Assay	-	IC50=11.0737 μM	SANGER
TK10	-	Growth Inhibition Assay	-	IC50=28.2399 μM	SANGER
TYK-nu	-	Growth Inhibition Assay	-	IC50=20.2847 μM	SANGER
U-2-OS	-	Growth Inhibition Assay	-	IC50=42.2641 μM	SANGER
UMC-11	-	Growth Inhibition Assay	-	IC50=18.1788 μM	SANGER
VMRC-RCZ	-	Growth Inhibition Assay	-	IC50=28.941 μM	SANGER
WM-115	-	Growth Inhibition Assay	-	IC50=29.7607 μM	SANGER
YH-13	-	Growth Inhibition Assay	-	IC50=12.0346 μM	SANGER
YKG-1	-	Growth Inhibition Assay	-	IC50=19.962 μM	SANGER
ZR-75-30	-	Growth Inhibition Assay	-	IC50=43.0493 μM	SANGER
697	-	Growth Inhibition Assay	-	IC50=2.65331 μM	SANGER
8305C	-	Growth Inhibition Assay	-	IC50=24.4045 μM	SANGER
A101D	-	Growth Inhibition Assay	-	IC50=29.6472 μM	SANGER
A172	-	Growth Inhibition Assay	-	IC50=1.70355 μM	SANGER

PD173074 Catalog No. CSN12916

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