CAS No.: 459836-30-7
PEAQX Catalog No. CSN17346
Synonyms: NVP-AAM077;AAM 007
PEAQX is a potent and orally active NMDA antagonist with a 15-fold preference for human NMDA receptors with the 1A/2A (IC50=270 nM), rather than 1A/2B(29,600 nM).
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Anastasio NC, Xia Y, et al. Differential role of N-methyl-D-aspartate receptor subunits 2A and 2B in mediating phencyclidine-induced perinatal neuronal apoptosis and behavioral deficits. Neuroscience. 2009 Nov 10;163(4):1181-91.
- [2] Auberson YP, Allgeier H, et al. 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg Med Chem Lett. 2002 Apr 8;12(7):1099-102.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 459836-30-7 | 储存条件 |
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| 分子式 | C17H17BrN3O5P | 运输 | 蓝冰 | |
| 分子量 | 454.21 | 别名 | NVP-AAM077;AAM 007 |
