CAS No.: 104112-82-5
Phellodendrine chloride/盐酸黄柏碱 Catalog No. CSN19951
Synonyms: Phellodendrine (chloride);Phellodendrine Chloride;l-(-)-N-Methylcoreximine
Phellodendrine HCl, a natural product isolated and purified from the cortex Phellodendri chinensis with anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. Phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Jiang XY, Zhang HF, et al. [ILs-HPLC simultanesous determination of five alkaloids in phellodenddri chinensis cortex] . Zhongguo Zhong Yao Za Zhi. 2014 Oct;39(19):3808-12. Chinese.
- [2] Kim YJ, Lim HS, Kim Y, Lee J, Kim BY, Jeong SJ. Phytochemical Quantification and the In Vitro Acetylcholinesterase Inhibitory Activity of Phellodendron chinense and Its Components. Molecules. 2017 Jun 2;22(6):925
- [3] Su S, Wang X, Xi X, Zhu L, Chen Q, Zhang H, Qin Y, Yang B, Che N, Cao H, Zhong W, Wang B. Phellodendrine promotes autophagy by regulating the AMPK/mTOR pathway and treats ulcerative colitis. J Cell Mol Med. 2021 Jun;25(12):5707-5720
- [4] Li L, Huang T, Tian C, Xiao Y, Kou S, Zhou X, Liu S, Ye X, Li X. The defensive effect of phellodendrine against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway in zebrafish embryos. Life Sci. 2016 Jul 15;157:97-106
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 104112-82-5 | 储存条件 |
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| 分子式 | C20H24ClNO4 | 运输 | 蓝冰 | |
| 分子量 | 377.86 | 别名 | Phellodendrine (chloride);Phellodendrine Chloride;l-(-)-N-Methylcoreximine;盐酸黄柏碱 |
