CAS No.: 2543-94-4
Phellopterin/珊瑚菜素 Catalog No. CSN13863
Synonyms: 珊瑚菜素
Phellopterin, a natural product isolated and purified from the roots of Saposhnikovia divaricata, is a partial agonist of the central benzodiazepine receptors in vitro, shows cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM, and reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Zhao AH, Yang XB, et al. Biotransformation products of phellopterin by rat liver microsomes and the inhibition on NO production in LPS-activated RAW264.7 cells. J Asian Nat Prod Res. 2012;14(10):956-65.
- [2] Nizamutdinova IT, Jeong JJ, et al. Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells. Int Immunopharmacol. 2008 May;8(5):670-8.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 2543-94-4 | 储存条件 |
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| 分子式 | C17H16O5 | 运输 | 蓝冰 | |
| 分子量 | 300.31 | 别名 | 珊瑚菜素 |
