400-920-2911 sales@csnpharm.cn
您的位置 : 首页 / Membrane Transporter/Ion Channel / SGLT & Chalcones / Phloretin/根皮素
CAS No.: 60-82-2
Synonyms: NSC 407292;RJC 02792;Dihydronaringenin
Phloretin, a dihydrochalcone flavonoid, can inhibit the active transport of glucose into cells by SGLT1 and SGLT2. It is mainly found in fruit and roots of apple tree.
生物活性
实验方案
技术信息
CAS号 | 60-82-2 | 储存条件 |
|
|||||||
分子式 | C15H14O5 | 运输 | 蓝冰 | |||||||
分子量 | 274.27 | 别名 | NSC 407292;RJC 02792;Dihydronaringenin;根皮素 | |||||||
溶解度 |
|
动物实验配方 |
Cell Lines | Concentration | Assay Type | Time | Activity Description | Data Sources |
---|
H1299 cells | - | Function assay | 30 mins | Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake incubated for 15 mins prior to 2-deoxy-D-[3H]-glucose addition measured after 30 mins by liquid scintillation counting analysis, IC50=21.4 Μm | 24200808 |
PK15NTD cells | - | Function assay | - | Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation, Ki=32.28 μM | 19097778 |
靶点 | Description | IC50 |
---|
联系我们
官方电话:400-920-2911
二维码
微信公众号 CSN官网