CAS No.: 41743-41-3
Procyanidin A2/原花青素 A2 Catalog No. CSN11777
Synonyms: (+)-Epicatechin-(4β-8,2β-O-7)-epicatechin;Proanthocyanidin A2;Procyanidin dimer A2
Procyanidin A2, a natural product isolated and purified from the rhizomes of Belamcanda chinensis (L.) DC., blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression, and has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03553225 Healthy Men and Women Not Applicable Recruiting December 30, 2018 United Kingdom ... more >> King's College London Recruiting London, United Kingdom, SE1 9NH Contact: Mariam Bapir, M.Sc. 02074844162 ext 4162 mariam.bapir@kcl.ac.uk Collapse << NCT01687114 Urinary Tract Infection Not Applicable Completed - United States, Massachusetts ... more >> Jean Mayer USDA Human Nutrition Research Center on Aging Boston, Massachusetts, United States, 02111 Collapse << NCT01099150 Cardiovascular Disease Not Applicable Completed - United Kingdom ... more >> University of Aberdeen Rowett Institute of Nutrition and Health Aberdeen, Aberdeenshire, United Kingdom, AB21 9SB Collapse << - 更多
- 参考文献
- [1] De Taeye C, Caullet G, et al. Procyanidin A2 and Its Degradation Products in Raw, Fermented, and Roasted Cocoa. J Agric Food Chem. 2017 Mar 1;65(8):1715-1723.
- [2] Coleman SL, Kruger MC, et al. Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells. Int J Mol Sci. 2016 Nov 12;17(11).
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 41743-41-3 | 储存条件 |
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| 分子式 | C30H24O12 | 运输 | 蓝冰 | |
| 分子量 | 576.50 | 别名 | (+)-Epicatechin-(4β-8,2β-O-7)-epicatechin;Proanthocyanidin A2;Procyanidin dimer A2;Procyanidol A2;原花青素 A2 |
