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CAS No.: 98769-84-7
Synonyms: FCE20124 mesylate;PNU155950E mesylate;Reboxetine (mesylate)
Reboxetine Mesylate is a norepinephrine reuptake inhibitor (NRI) used in the treatment of unipolar depression.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02547818 | Alzheimer's Disease | Phase 3 | Recruiting | November 2019 | - |
NCT01224106 | Alzheimer's Disease | Phase 3 | Active, not recruiting | July 22, 2020 | - |
NCT02726386 | Parkinson's Disease | Phase 2 | Active, not recruiting | August 2021 | - |
实验方案
技术信息
CAS号 | 98769-84-7 | 储存条件 |
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分子式 | C20H27NO6S | 运输 | 蓝冰 | |||||
分子量 | 409.50 | 别名 | FCE20124 mesylate;PNU155950E mesylate;Reboxetine (mesylate);FCE 20124;PNU 155950E;Reboxetine Mesylate;Reboxetine mesilate;Edronax;Vestra (TN);AC1L2RIX;AC1Q6WCV;DSSTox_CID_25690;DSSTox_RID_81062;DSSTox_GSID_45690;甲磺酸瑞波西汀 | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02547818 | Alzheimer's Disease | Phase 3 | Recruiting | November 2019 | - |
NCT01224106 | Alzheimer's Disease | Phase 3 | Active, not recruiting | July 22, 2020 | - |
NCT02726386 | Parkinson's Disease | Phase 2 | Active, not recruiting | August 2021 | - |
NCT03202979 | Painful Diabetic Neuropathy | Phase 2 | Completed | - | Czechia ... more >> NEUROHK s.r.o. Chocen, Czechia, 565 01 Litnea s.r.o. Neurologicka ambulance Litomerice, Czechia, 412 01 Neurosanatio s.r.o. Litomysl, Czechia, 570 01 MP-neuro s.r.o. Poliklinika Modry pavilon Ostrava, Czechia, 710 00 Nemocnice Pardubickeho kraje a.s. Pardubicka nemocnice Neurologická klinika Pardubice, Czechia, 532 03 Diabetologicka ambulance Milan Kvapil s.r.o. Praha 4, Czechia, 149 00 Vestra Clinics s.r.o. Rychnov nad Knežnou, Czechia, 516 01 Hungary Budai Irgalmasrendi Korhaz Belgyógyászati Centrum Budapest, Hungary, 1027 Semmelweis Egyetem AOK I. sz. Belgyogyaszati Klinika Budapest, Hungary, 1083 Markhot Ferenc Oktatokorhaz es Rendelointezet Diabetesz Gondozo Eger, Hungary, 3300 Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz I. sz. Belgyogyaszati Osztaly Gyula, Hungary, 5700 Bacs-Kiskun Megyei Korhaz II. sz. Belgyogyaszati Osztaly Kecskemet, Hungary, 6000 Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont I. Sz. Belgyogyaszati Klinika Szeged, Hungary, 6720 Poland Silmedic Sp. z o.o. Katowice, Poland, 40-282 Pro Familia Altera Sp. z o.o. Katowice, Poland, 40-648 NZOZ Neuromed M. i M. Nastaj Sp. P. Lublin, Poland, 20-064 RCMed Oddział Sochaczew Sochaczew, Poland, 96-500 Jeka Sławomir Niepubliczny Zakład Opieki Zdrowotnej "Nasz Lekarz" Praktyka Grupowa Lekarzy Rodzinnych z Przychodnia Specjalistyczna Torun, Poland, 87-100 NBR Polska Tomasz Klodawski Warszawa, Poland, 00-465 Medycyna Kliniczna Warszawa, Poland, 00-660 Collapse << |
NCT03325556 | Dementia-related Psychosis | Phase 3 | Recruiting | March 2020 | - |
NCT03402659 | Alzheimer Disease | Phase 2 | Recruiting | July 31, 2019 | - |
NCT02374567 | Dementia Depr... more >>ession Schizophrenia Psychosomatic Disorders Anxiety Disorders Collapse << | Phase 3 | Terminated | - | Germany ... more >> Bezirkskrankenhaus Augsburg Augsburg, Germany Krankenhaus Hedwigshöhe Berlin, Germany Hannover Medical School Hannover, Germany, 30625 Asklepios Fachklinikum Lübben Lübben, Germany Asklepios Fachklinikum Teupitz Teupitz, Germany Collapse << |
NCT00613067 | Generalized Anxiety Disorder | Not Applicable | Completed | - | Korea, Republic of ... more >> Psychiatry department, Inje Univ. Ilsanpaik Hospital Goyang, Kyunggi, Korea, Republic of, 414-410 Collapse << |
NCT01357967 | Major Depressive Disorder | Phase 4 | Unknown | April 2013 | Korea, Republic of ... more >> Psychiatry Department, Inje University Ilsan Paik Hospital Recruiting Goyang, Geyonggi, Korea, Republic of Principal Investigator: Seung-Hwan Lee, MD, PhD Inje University Ilsanpaik Hospital Active, not recruiting Goyang, Gyeonggi, Korea, Republic of, 411-706 Collapse << |
NCT00953108 | Major Depression | Phase 3 | Completed | - | Germany ... more >> Department of Psychiatry, Ludwig-Maximilian-University Munich, Bavaria, Germany, 80336 Collapse << |
NCT00138749 | Urinary Incontinence, Stress | Phase 2 | Completed | - | - |
NCT00817323 | Bipolar Depression | Phase 3 | Withdrawn(Recruitment did not ... more >>take place for this research due to several delays and then one of the PIs moved out of the country and the project was closed) Collapse << | December 2013 | - |
NCT02874937 | Syncope, Vasovagal | Phase 2 | Unknown | April 2017 | Canada, Alberta ... more >> University of Calgary, Faculty of Medicine Recruiting Calgary, Alberta, Canada, T2N 4N1 Contact: Dr. Satish Raj, MD satish.raj@ucalgary.ca Principal Investigator: Robert S. Sheldon, MD, PhD Collapse << |
NCT00141128 | Urinary Incontinence, Stress | Phase 2 | Completed | - | Denmark ... more >> Pfizer Investigational Site Glostrup, Denmark, 2600 Collapse << |
NCT03069014 | Mild to Moderate Alzheimer's D... more >>isease Collapse << | Phase 1 Phase 2 | Recruiting | October 31, 2019 | Austria ... more >> University Hospital Graz Recruiting Graz, Styria, Austria, 8034 Contact: Birgit Reinhart +43 316 385 833 96 birgit.reinhart@medunigraz.at Principal Investigator: Reinhold Schmidt, Prof. Dr. Sub-Investigator: Anita Lechner, Dr. med. Landeskrankenhaus Hall Recruiting Hall in Tirol, Tirol, Austria, 6060 Contact: Elisabeth Klingler +43 50504 88265 elisabeth.klingler@tirol-kliniken.at Principal Investigator: Douglas Imarhiagbe, OA Dr. med. Sub-Investigator: Cornelia Hessler-Piock, Dr. med. Czechia Charles University Recruiting Praha, Hlavni Mesto Praha, Czechia, 16000 Contact: Marcela Sedlackova +42 0 702 001 917 marcelasedlackova@seznam.cz Principal Investigator: Jakub Hort, Prof. MD Sub-Investigator: Jan Lazco, MD Neurology Clinic of Martin Urbanek Recruiting Brno, Jihomoravsky Kraj, Czechia, 60200 Contact: Jana Pacinkova 00420 737 157 670 j.pacinkova@gmail.com Principal Investigator: Katerina Sheardová, MD Sub-Investigator: Martin Urbanek, MD Vestra clinics s.r.o Recruiting Rychnov nad Kneznou, Kralovehadrecky Kraj, Czechia, 51601 Contact: Jitka Adamcova +42 0607 818683 jitka@vestraclinics.org Principal Investigator: Ladislav Pazdera, MD Sub-Investigator: Veselý Pazdera, MD NEUROHK s.r.o Recruiting Chocen, Pardubicky Kraj, Czechia, 56501 Contact: Jitka Prouzová +420 604 444 808 kucerjiri@gmail.com Principal Investigator: Martin Valis, MD Sub-Investigator: Petr Barton, MD Germany Nordwestkrankenhaus Sanderbusch Recruiting Sande, Friesland, Germany, 26452 Contact: Christina Eiben +49 4422 80-1434 c.eiben@sanderbusch.de Contact: Anne Stargardt a.stargardt@sanderbusch.de Principal Investigator: Pawel Kermer, Prof.Dr.med Sub-Investigator: Deeg Sebastian, Dr.med Zentrum für klinische Forschung Recruiting Bad Homburg, Hesse, Germany, 61348 Contact: Justine Orth +49 6172 1710784 justineorth@dr-schoell.de Contact: Rebecca Schwegler rebeccaschwegler@dr-schoell.de Principal Investigator: Irma Schöll, MD Sub-Investigator: Elvira Steidl, MD Studienzentrum Nordwest Recruiting Westerstede, Niedersachsen, Germany, 26655 Contact: Irene Reinisch +49 448852 1500 ireinisch@studienzentrum-nordwest.de Contact: Nicole Mildt nmildt@studienzentrum-nordwest.de Principal Investigator: Joachim Springub, Dr. med. Sub-Investigator: Wolfgang Schwarz, Dr. med. Universitätsklinik Magdeburg, Klinik für Neurologie Recruiting Magdeburg, Sachsen Anthal, Germany, 39120 Contact: Urte Schneider urte.schneider@med.ovgu.de Principal Investigator: Daniel Bittner, MD Sub-Investigator: Peter Körtvelyessy, MD Sächsisches Krankenhaus Arnsdorf Recruiting Arnsdorf, Sachsen, Germany, 01477 Contact: Ramona Rost +49 35200 26-2270 Ramona.Rost@skhar.sms.sachsen.de Principal Investigator: Peter Schönknecht, Prof. Dr. Sub-Investigator: Majdy Abu Bakr, OA Dr. Pharmakologisches Studienzentrum Chemnitz GmbH Recruiting Chemnitz, Sachsen, Germany Contact: Anne Merkel +49 3727 991006 merkel@mvz-mittweida.de Principal Investigator: Ralf Bodenschatz, Dipl.-med. Sub-Investigator: Gunter Schumann, Dr. med. Charité Universitätsmedizin Berlin Recruiting Berlin, Germany, 13125 Contact: Nadine Krüger +49 3045 540097 nadine.krueger@charite.de Principal Investigator: Oliver Peters, Doz. Dr. Sub-Investigator: Heidrun Mehling, Dr. med. Neurologie Sendlinger Strasse Studien- und Gedächtniszentrum München Recruiting München, Germany, 80331 Contact: Susanne Dombrowka susanne.dombrowka@web.de Contact: Barbara Wittek goodmeds@web.de Principal Investigator: Andrej Pauls, Dipl.Psy.MD Sub-Investigator: Susanne Adel, MD LMU München Klinik für Psychiatrie und Psychotherapie Recruiting München, Germany, 80336 Contact: Thomas Görlitz thomas.goerlitz@med.uni-muenchen.de Principal Investigator: Robert Perneczky, Prof. MD Sub-Investigator: Carolin Kurz, MD Spain Fundació ACE Not yet recruiting Barcelona, Catalonia, Spain, 08028 Contact: Mar Buendia +34 - 93 430 47 20 Principal Investigator: Mercé Boada Rovira, MD Fundación de Gestión Sanitaria del Hospital de la Santa Creu I Sant Pau, C Not yet recruiting Barcelona, Catalonia, Spain, 08036 Contact: Roser Ribosa +34 - 93 553 71 12 Principal Investigator: Rafael Blesa González, MD Hospital Clínic de Barcelona Not yet recruiting Barcelona, Catalonia, Spain, 08036 Contact: Guadalupe Fernández Principal Investigator: Raquel Sánchez del Valle, MD Hospital la Paz Not yet recruiting Madrid, Spain, 28046 Contact: Ana Frank García, Prof. MD. Contact: Vega Mauleón Principal Investigator: Ana Frank García, Prof. MD. Hospital Virgen del Rocío Not yet recruiting Sevilla, Spain, 41013 Contact: Antonio Cervera Barajas +34-955-01 43 57 Principal Investigator: Emilio Franco Macías, MD Sweden Karolinska University Not yet recruiting Stockholm, Stockholms Iän, Sweden, 14186 Contact: Malin Aspö +46 8 585 854 68 malin.aspo@karolinska.se Principal Investigator: Niels Andreasen, Prof.Dr. Collapse << |
NCT00993876 | Cognitive Performance in Major... more >> Depression Collapse << | Not Applicable | Completed | - | Germany ... more >> Zentrum für Integrative Psychiatrie Kiel, Germany, 24105 Collapse << |
NCT02179268 | Bone Mineral Density Quantitat... more >>ive Trait Locus 7 Collapse << | Phase 3 | Completed | - | - |
NCT00421369 | Major Depressive Disorder | Not Applicable | Completed | - | Israel ... more >> Hadassah Medical Organization Jerusalem, Israel Collapse << |
NCT00625833 | Diabetic Neuropathies | Phase 2 | Terminated(Study was terminate... more >>d for futility following the planned interim analysis.) Collapse << | - | - |
NCT00562055 | Attention Deficit Hyperactivit... more >>y Disorder Collapse << | Phase 2 | Withdrawn(This study was withd... more >>rawn due to business reasons.) Collapse << | - | - |
NCT00607256 | Fibromyalgia | Phase 3 | Terminated | - | - |
NCT00143442 | Pain | Phase 2 | Completed | - | - |
NCT00636246 | Depressive Disorder, Major | Phase 2 | Completed | - | Estonia ... more >> Pfizer Investigational Site Viljandi, Viljandi mk., Estonia, 71024 Pfizer Investigational Site Pärnu, Estonia, 80012 Pfizer Investigational Site Tallinn, Estonia, 10614 Pfizer Investigational Site Tartu, Estonia, 51008 Russian Federation Pfizer Investigational Site Moscow, Russia, Russian Federation Pfizer Investigational Site St. Petersburg, Russia, Russian Federation, 192019 Pfizer Investigational Site Kazan, Russian Federation, 420012 Pfizer Investigational Site Moscow, Russian Federation, 107076 Pfizer Investigational Site Moscow, Russian Federation, 115522 Pfizer Investigational Site Moscow, Russian Federation, 119034 Pfizer Investigational Site Moscow, Russian Federation, 127473 Pfizer Investigational Site Moscow, Russian Federation Pfizer Investigational Site Rostov On Don, Russian Federation, 344010 Pfizer Investigational Site Smolensk, Russian Federation, 214019 Pfizer Investigational Site St Petersburg, Russian Federation, 190121 Pfizer Investigational Site St. Petersburg, Russian Federation, 192019 Pfizer Investigational Site St. Petersburg, Russian Federation, 193167 Pfizer Investigational Site St. Petersburg, Russian Federation, 194214 Pfizer Investigational Site Tomsk, Russian Federation, 634014 Collapse << |
NCT00444548 | Healthy | Not Applicable | Completed | - | Denmark ... more >> Pfizer Investigational Site Hellerup, Denmark, 2900 Collapse << |
NCT00354094 | Pain | Phase 2 | Terminated(The study was stopp... more >>ed due to business/operational issues.) Collapse << | - | - |
NCT00357825 | Pain | Phase 2 | Completed | - | - |
NCT00288652 | Pain | Phase 2 | Completed | - | - |
NCT00853866 | Cerebral Stroke | Phase 4 | Completed | - | Germany ... more >> University Hospital Hamburg-Eppendorf, Department of Neurology Hamburg, HH, Germany, 20246 Collapse << |
NCT00348894 | Pain | Phase 2 | Terminated(- Study was termina... more >>ted due to insufficient clinical efficacy observed in previous studies conducted in postherpetic neuralgia.) Collapse << | - | - |
NCT00612170 | Fibromyalgia | Phase 3 | Completed | - | - |
NCT00426946 | Depression | Phase 4 | Unknown | - | Israel ... more >> Tel Aviv Community Mental Helath Center Recruiting Tel Aviv, Israel Contact: Paz Toren, MD 972522248287 ptoren@post.tau.ac.il Collapse << |
NCT00334685 | Pain | Phase 2 | Terminated(The DMC terminated ... more >>the study on the basis of futility (insufficient clinical response).) Collapse << | - | - |
NCT01300364 | Schizophrenia | Phase 4 | Unknown | - | Spain ... more >> Parc Sanitari Sant Joan de Déu Recruiting Sant Boi Llobregat, Barcelona, Spain Contact: Judith Usall 93 6002650 ext 2356 jusall@pssjd.org Collapse << |
NCT00409201 | Schizophrenia | Phase 1 | Unknown | - | Israel ... more >> Abarbanel Medical Mental Health Center Recruiting Bat Yam, Israel, 59100 Contact: stanislav baranchik, md 972-3-5552625 Contact: alex aviv, md 972-3-552703 alexaviv@gmail.com Principal Investigator: stanislav baranchik, md Abarbanel Medical Mental Health Center Recruiting Bat Yam, Israel, 59100 Principal Investigator: stanislav baranchik, md Collapse << |
NCT00754221 | Fibromyalgia | Phase 3 | Terminated(This study has been... more >> terminated early as the esreboxetine development program is being discontinued. There are no safety or efficacy concerns.) Collapse << | - | - |
NCT00353808 | Pain | Phase 2 | Terminated(This study has been... more >> terminated early as the esreboxetine development program is being discontinued. There are no safety or efficacy concerns.) Collapse << | - | - |
NCT00209807 | Major Depression ... more >> Pain Abdominal Pain Collapse << | Phase 4 | Unknown | April 2011 | Spain ... more >> Hospital Universitari vall d'Hebron Recruiting Barcelona, Catalonia, Spain, 08036 Contact: Josep Antoni Ramos-Quiroga, MD 0034 93 489 42 94 jaramos@vhebron.net Contact: Xavier Castells, MD 0034 93 489 42 94 xcc@icf.uab.cat Principal Investigator: Miguel Casas, Prof Sub-Investigator: Josep Antoni Ramos-Quiroga, MD Principal Investigator: Juan-R Malagelada, MD Sub-Investigator: Fernando Azpiroz, MD Sub-Investigator: Rosa Bosch Munso Sub-Investigator: Gemma Parramon Sub-Investigator: Xavier Castells Cervelló, MD Sub-Investigator: Anna Accarino, MD Sub-Investigator: Jordi Serra, MD Collapse << |
NCT00886886 | Mood Disorder ... more >> Substance-related Disorders Amphetamine-related Disorders Collapse << | Phase 1 | Completed | - | Switzerland ... more >> University Hospital Basel, Switzerland Collapse << |
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