CAS No.: 854056-07-8
Ropivacaine mesylate/甲磺酸罗哌卡因 Catalog No. CSN27571
Synonyms: Ropivacaine Mesylate;甲磺酸罗哌卡因
Ropivacaine mesylate is a long-acting amide local anaesthetic agent for a spinal block and effectively blocks neuropathic pain. Ropivacaine blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibressup>. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 参考文献
- [1] Li TF, et al. Epidural sustained release ropivacaine prolongs anti-allodynia and anti-hyperalgesia in developing and established neuropathic pain. PLoS One. 2015 Jan 24;10(1):e0117321.
- [2] Milan Patel, et al. Ropivacaine Inhibits Pressure-Induced Lung Endothelial Hyperpermeability in Models of Acute Hypertension. Life Sci. 2019 Apr 1;222:22-28.
- [3] Dene Simpson, et al. Ropivacaine: a review of its use in regional anaesthesia and acute pain management. Drugs. 2005;65(18):2675-717.
- [4] Hye Won Shin, et al. The inhibitory effects of bupivacaine, levobupivacaine, and ropivacaine on K2P (two-pore domain potassium) channel TREK-1. J Anesth. 2014 Feb;28(1):81-6.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 854056-07-8 | 储存条件 |
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| 分子式 | C18H30N2O4S | 运输 | 蓝冰 | |||
| 分子量 | 370.51 | 别名 | Ropivacaine Mesylate;甲磺酸罗哌卡因 | |||
| 溶解度 |
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动物实验配方 |
