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CAS No.: 126-19-2
Synonyms: Parigenin;Sarsagenin;NSC 1615
Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00875316 | Parkinson's Disease | Phase 1 | Completed | - | United Kingdom ... more >> LCG Bioscience Bourn, Cambridgeshire, United Kingdom, CB23 2TN Collapse << |
NCT01060878 | Parkinson's Disease | Phase 2 | Completed | - | - |
NCT00130429 | Alzheimer's Disease | Phase 2 | Completed | - | United Kingdom ... more >> Oxford Project to Investigate Memory and Ageing Oxford, Oxfordshire, United Kingdom, OX3 7JX Collapse << |
实验方案
技术信息
CAS号 | 126-19-2 | 储存条件 |
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分子式 | C27H44O3 | 运输 | 蓝冰 | |
分子量 | 416.64 | 别名 | Parigenin;Sarsagenin;NSC 1615;PYM-50018;Myogane;菝葜皂苷元 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00875316 | Parkinson's Disease | Phase 1 | Completed | - | United Kingdom ... more >> LCG Bioscience Bourn, Cambridgeshire, United Kingdom, CB23 2TN Collapse << |
NCT01060878 | Parkinson's Disease | Phase 2 | Completed | - | - |
NCT00130429 | Alzheimer's Disease | Phase 2 | Completed | - | United Kingdom ... more >> Oxford Project to Investigate Memory and Ageing Oxford, Oxfordshire, United Kingdom, OX3 7JX Collapse << |
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