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CAS No.: 184036-34-8
Synonyms: IPI 1040;TBC-11251
Sitaxsentan is a selective endothelin A (ETA) receptor antagonist.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01347216 | - | - | Recruiting | June 2020 | Belgium ... more >> Dept. of Pneumology, University Recruiting Leuven, Belgium Contact: Marion Delcroix, MD, PhD Principal Investigator: Marion Delcroix, MD, PhD Germany DRK-Klinikum Köpenick Recruiting Berlin, Germany Contact: Christian Opitz, MD, PhD Principal Investigator: Christian Opitz, MD, PhD Lung Centre, University of Giessen Recruiting Giessen, Germany Contact: Ardeschir Ghofrani, MD, PhD Principal Investigator: Ardeschir Ghofrani, MD Sub-Investigator: Melanie Thamm, MD Department of Pulmology; Hannover Medical School Recruiting Hannover, Germany Contact: Marius M Hoeper Principal Investigator: Marius M Hoeper, MD, PhD Sub-Investigator: Karen Olsson, MD German Heart Centre Recruiting Munich, Germany Contact: Harald Kaemmerer, MD,. PhD Principal Investigator: Harald Kaemmerer, MD, PhD Ireland Mater Misericordiae Recruiting Dublin, Ireland Contact: Sean Gaine, MD, PhD Principal Investigator: Sean Gaine, MD, PhD Italy Department of Cardiovascular and Respiratory Sciences, University La Sapienza Recruiting Rome, Italy Contact: Dario Vizza, MD, PhD Principal Investigator: Dario Vizza, MD, PhD Switzerland Dept. for Rheumatology, University Hospital Recruiting Zurich, Switzerland Contact: Oliver Distler, MD, PhD Principal Investigator: Oliver Distler, MD, PhD Collapse << |
NCT00995566 | - | - | Terminated(The trial was prema... more >>turely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.") Collapse << | - | Belgium ... more >> Pfizer Investigational Site Bruxelles, Belgium, 1070 Pfizer Investigational Site Leuven, Belgium, 3000 France Pfizer Investigational Site Nice, France, 06000 Germany Pfizer Investigational Site Hannover, Germany, 30625 Collapse << |
NCT00423592 | Pulmonary Hypertension | Phase 2 | Completed | - | - |
实验方案
技术信息
CAS号 | 184036-34-8 | 储存条件 |
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分子式 | C18H15ClN2O6S2 | 运输 | 蓝冰 | |
分子量 | 454.90 | 别名 | IPI 1040;TBC-11251 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01347216 | - | - | Recruiting | June 2020 | Belgium ... more >> Dept. of Pneumology, University Recruiting Leuven, Belgium Contact: Marion Delcroix, MD, PhD Principal Investigator: Marion Delcroix, MD, PhD Germany DRK-Klinikum Köpenick Recruiting Berlin, Germany Contact: Christian Opitz, MD, PhD Principal Investigator: Christian Opitz, MD, PhD Lung Centre, University of Giessen Recruiting Giessen, Germany Contact: Ardeschir Ghofrani, MD, PhD Principal Investigator: Ardeschir Ghofrani, MD Sub-Investigator: Melanie Thamm, MD Department of Pulmology; Hannover Medical School Recruiting Hannover, Germany Contact: Marius M Hoeper Principal Investigator: Marius M Hoeper, MD, PhD Sub-Investigator: Karen Olsson, MD German Heart Centre Recruiting Munich, Germany Contact: Harald Kaemmerer, MD,. PhD Principal Investigator: Harald Kaemmerer, MD, PhD Ireland Mater Misericordiae Recruiting Dublin, Ireland Contact: Sean Gaine, MD, PhD Principal Investigator: Sean Gaine, MD, PhD Italy Department of Cardiovascular and Respiratory Sciences, University La Sapienza Recruiting Rome, Italy Contact: Dario Vizza, MD, PhD Principal Investigator: Dario Vizza, MD, PhD Switzerland Dept. for Rheumatology, University Hospital Recruiting Zurich, Switzerland Contact: Oliver Distler, MD, PhD Principal Investigator: Oliver Distler, MD, PhD Collapse << |
NCT00995566 | - | - | Terminated(The trial was prema... more >>turely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.") Collapse << | - | Belgium ... more >> Pfizer Investigational Site Bruxelles, Belgium, 1070 Pfizer Investigational Site Leuven, Belgium, 3000 France Pfizer Investigational Site Nice, France, 06000 Germany Pfizer Investigational Site Hannover, Germany, 30625 Collapse << |
NCT00423592 | Pulmonary Hypertension | Phase 2 | Completed | - | - |
NCT00423592 | - | - | Completed | - | - |
NCT00995566 | - | - | Terminated(The trial was prema... more >>turely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.") Collapse << | - | - |
NCT01281371 | - | - | Completed | - | Germany ... more >> Department of Clinical Pharmacology and Pharmacoepidemiology, Medical department of the University of Heidelberg Heidelberg, Baden-Württemberg, Germany, 69120 Collapse << |
NCT00593905 | - | - | Unknown | July 2013 | United States, Pennsylvania ... more >> Allegheny General Hospital Recruiting Pittsburgh, Pennsylvania, United States, 15212 Contact: Andrea L Nowicki, BA 412-359-3653 anowicki@wpahs.org Contact: Raymond L Benza, MD 412.359.3584 rbenza@wpahs.org Principal Investigator: Raymond L Benza, MD Collapse << |
NCT00744211 | - | - | Completed | - | - |
NCT00981968 | Healthy | Phase 1 | Completed | - | United States, California ... more >> Pfizer Investigational Site Glendale, California, United States, 91206 Collapse << |
NCT00080457 | Pulmonary Hypertension | Phase 3 | Completed | - | United States, Texas ... more >> Encysive Pharmaceuticals Houston, Texas, United States, 77401 Collapse << |
NCT01100736 | Pulmonary Arterial Hypertensio... more >>n Vasodilation Vasoconstriction Collapse << | Early Phase 1 | Completed | - | United Kingdom ... more >> Clinical Research Centre, Western General Hospital Edinburgh, Scotland, United Kingdom, EH4 2XU Collapse << |
NCT00034307 | Pulmonary Hypertension | Phase 2 Phase 3 | Unknown | - | - |
NCT00744211 | Heart Disease | Not Applicable | Completed | - | United States, South Carolina ... more >> Ralph H. Johnson VA Medical Center, Charleston, SC Charleston, South Carolina, United States, 29401-5799 Collapse << |
NCT01251848 | Pulmonary Arterial Hypertensio... more >>n Collapse << | Phase 1 | Withdrawn | February 2011 | - |
NCT00303498 | Diastolic Heart Failure | Phase 2 | Completed | - | - |
NCT01244620 | - | - | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | - |
NCT01210443 | Hypertension, Pulmonary | Phase 3 | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | Japan ... more >> Pfizer Investigational Site Nagoya, Aichi, Japan Pfizer Investigational Site Shinjyuku-ku, Tokyo, Japan Collapse << |
NCT01204853 | Hypertension, Pulmonary | Phase 3 | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | Japan ... more >> Pfizer Investigational Site Nagoya, Aichi, Japan Pfizer Investigational Site Shinjyuku-ku, Tokyo, Japan Collapse << |
NCT01244620 | Pulmonary Arterial Hypertensio... more >>n Collapse << | Phase 1 | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | Singapore ... more >> Pfizer Investigational Site Singapore, Singapore, 188770 Collapse << |
NCT01445873 | - | - | Completed | - | - |
NCT01445873 | - | - | Completed | - | - |
NCT01210443 | - | - | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | - |
NCT00838383 | Cardiac Surgery Subjects ... more >> Subjects Undergoing CABG and/or Cardiac Valve Replacement Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Pfizer Investigational Site Philadelphia, Pennsylvania, United States, 19104 United States, South Carolina Pfizer Investigational Site Charleston, South Carolina, United States, 29425 United States, Tennessee Pfizer Investigational Site Chattanooga, Tennessee, United States, 37404 Collapse << |
NCT00796510 | Pulmonary Arterial Hypertensio... more >>n Pulmonary Hypertension Collapse << | Phase 3 | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury) Collapse << | - | United States, California ... more >> Pfizer Investigational Site Fountain Valley, California, United States, 92708 Romania Pfizer Investigational Site Cluj Napoca, Romania, 400 001 Ukraine Pfizer Investigational Site Kyiv, Ukraine Collapse << |
NCT01204853 | - | - | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | - |
NCT00796666 | Pulmonary Arterial Hypertensio... more >>n Pulmonary Hypertension Collapse << | Phase 3 | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | - |
NCT01050491 | Effect of Sitaxsentan on Airwa... more >>y Remodeling in Severe Asthma Collapse << | Phase 2 | Terminated(sitaxentan is not c... more >>ommercialized anymore) Collapse << | - | France ... more >> Clinical Investigation center 07, Hopital Bichat Paris, France, 75018 Collapse << |
NCT00817037 | Chronic Kidney Disease ... more >> Proteinuria Blood Pressure Collapse << | Phase 2 | Unknown | - | United Kingdom ... more >> Clinical Research Centre, Western General Hospital Edinburgh, Scotland, United Kingdom, EH4 2XU Collapse << |
NCT00810732 | Chronic Kidney Disease ... more >> CRD Collapse << | Phase 2 | Completed | - | United Kingdom ... more >> Pfizer Investigational Site Edinburgh, Scotland, United Kingdom, EH4 2XU Collapse << |
NCT00811018 | Pulmonary Arterial Hypertensio... more >>n Collapse << | Phase 3 | Terminated(This trial was prem... more >>aturely terminated on Dec 9 2010 due to safety concerns, specifically emerging evidence of hepatic injury.) Collapse << | - | - |
NCT00795639 | Pulmonary Arterial Hypertensio... more >>n Pulmonary Hypertension Collapse << | Phase 3 | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | - |
NCT00796510 | - | - | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury) Collapse << | - | - |
NCT00796666 | - | - | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | - |
NCT01251835 | Pulmonary Arterial Hypertensio... more >>n Collapse << | Phase 1 | Withdrawn | January 2011 | - |
NCT00795639 | - | - | Terminated(Safety Issue The tr... more >>ial was prematurely terminated on Dec 9, 2010, due to safety concerns, specifically new emerging evidence of hepatic injury.) Collapse << | - | - |
NCT00811018 | - | - | Terminated(This trial was prem... more >>aturely terminated on Dec 9 2010 due to safety concerns, specifically emerging evidence of hepatic injury.) Collapse << | - | - |
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