CAS No.: 1218778-77-8
Sonidegib diphosphate Catalog No. CSN17578
Synonyms: Erismodegib diphosphate;LDE225 diphosphate;NVP-LDE225 diphosphate
LDE225 diphosphate is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Irvine DA, Zhang B, et al. Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia. Sci Rep. 2016 May 9;6:25476.
- [2] Pan S, Wu X, et al. Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist. ACS Med Chem Lett. 2010 Mar 16;1(3):130-4.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1218778-77-8 | 储存条件 |
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| 分子式 | C26H32F3N3O11P2 | 运输 | 蓝冰 | |
| 分子量 | 681.49 | 别名 | Erismodegib diphosphate;LDE225 diphosphate;NVP-LDE225 diphosphate;LDE225 (phosphate);Erismodegib;NVP-LDE225;Sonidegib;LDE-225;Sonidegib phosphate;Odomzo |
