CAS No.: 848463-13-8
SSR128129E free acid Catalog No. CSN18466
Synonyms: SSR free acid
SSR128129E free acid is a multi-FGFR blocker with allosteric properties and inhibits FGFR signaling by binding to the extracellular FGFR domain without affecting orthosteric FGF binding.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Bono F, De Smet F, et al. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell. 2013 Apr 15;23(4):477-88.
- [2] Dol-Gleizes F, Delesque-Touchard N, et al. A new synthetic FGF receptor antagonist inhibits arteriosclerosis in a mouse vein graft model and atherosclerosis in apolipoprotein E-deficient mice. PLoS One. 2013 Nov 4;8(11):e80027.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 848463-13-8 | 储存条件 |
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| 分子式 | C18H16N2O4 | 运输 | 蓝冰 | |
| 分子量 | 324.33 | 别名 | SSR free acid |
