CAS No.: 5812-07-7
SU4312 Catalog No. CSN20550
SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively), which is selective over EGFR and c-Src tyrosine kinases.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Guo B, Hu S, et al. Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B. Neuropharmacology. 2017 Aug 11. pii: S0028-3908(17)30381-7.
- [2] Cui W, Zhang Z, et al. The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS. Br J Pharmacol. 2013 Mar;168(5):1201-14.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 5812-07-7 | 储存条件 |
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| 分子式 | C17H16N2O | 运输 | 蓝冰 | |
| 分子量 | 264.32 | 别名 |
