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CAS No.: 1312691-33-0
TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL)[1][2][3][4].
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实验方案
技术信息
CAS号 | 1312691-33-0 | 储存条件 |
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分子式 | C17H21FN6O | 运输 | 蓝冰 | |
分子量 | 344.39 | 别名 |
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