CAS No.: 51543-40-9
Tarenflurbil/R-氟比洛芬 Catalog No. CSN12719
Synonyms: (R)-Flurbiprofen;MPC7869;E-7869
(R)-Flurbiprofen is the R-enantiomer of the racemate NSAID flurbiprofen, inhibiting the binding of [3H]9-cis-RA to RXRαLBD with IC50 of 75 μM.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02438072 Depression Not Applicable Unknown December 2015 Switzerland ... more >> Hôpitaux Universitaires de Genève Recruiting Genève, Switzerland, 1205 Contact: celia Lloret-Linares, MD, PhD 0041 79 55 36 389 celia.LloretLinares@hcuge.ch Collapse << NCT01061112 - - Unknown June 2014 United States, Minnesota ... more >> Clinical and Translational Science Institute Minneapolis, Minnesota, United States, 55414 Collapse << NCT00425451 Periodontitis Phase 2 Completed - Israel ... more >> Hadassah Medical Organization Jerusalem, Israel, 91120 Collapse << - 更多
- 参考文献
- [1] Wanngren J, Ottervald J, et al. Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production. J Biol Chem. 2012 Sep 21;287(39):32640-50.
- [2] You X, Zhang YW, Cet al. Retinoid X receptor-alpha mediates (R )-flurbiprofen's effect on the levels of Alzheimer's beta-amyloid. J Neurochem. 2009 Oct;111(1):142-9.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 51543-40-9 | 储存条件 |
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| 分子式 | C15H13FO2 | 运输 | 蓝冰 | |
| 分子量 | 244.26 | 别名 | (R)-Flurbiprofen;MPC7869;E-7869;Furbiprofen;R-氟比洛芬 |
