CAS No.: 2564-83-2
Tempo/2,2,6,6-四甲基哌啶-1-氧自由基 Catalog No. CSN27569
Synonyms: TempoTempo;AI3-51508
Tempo is a classic nitroxide radical and is a selective scavenger of mitochondrial ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 参考文献
- [1] Du K, et al. Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity. Arch Toxicol. 2017 Feb;91(2):761-773.
- [2] Guo X, et al. Comparative Genotoxicity of TEMPO and 3 of Its Derivatives in Mouse Lymphoma Cells. Toxicol Sci. 2018 May 1;163(1):214-225.
- [3] Lv H, et al. TEMPO catalyzed oxidative dehydrogenation of hydrazobenzenes to azobenzenes. Org Biomol Chem. 2020 Apr 22.
- [4] Chen X, et al. Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling. Br J Cancer. 2020 May 5.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 2564-83-2 | 储存条件 |
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| 分子式 | C9H18NO | 运输 | 蓝冰 | |||
| 分子量 | 156.25 | 别名 | TempoTempo;AI3-51508 | |||
| 溶解度 |
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动物实验配方 |
